Publications

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the problem of bacterial resistance to antibiotics among strains isolated from hospital patients in lagos and ibadan, nigeria.bacterial infections are still an important cause of illness and death in developing countries, where the widespread and indiscriminate use of antibiotics has led to serious problems of resistance to the older, less expensive agents. the results of routine sensitivity testing of clinical isolates from patients in lagos and ibadan, nigeria show a high prevalence of strains resistant to penicillin, tetracycline, ampicillin, co-trimoxazole and chloramphenicol, with between 70% and 90% of strains of ...19892745266
clinical trial of cefoxitin (mefoxin) in parenteral therapy of septicemia (postabortal and postpartum) in ibadan.cases of post-abortal sepsis are admitted every day into the university college hospital (uch), ibadan, nigeria. this derives from the high incidence of induced (illegal) abortions in this environment. the infections are usually caused by mixed bacterial flora, often resistant to the common antibiotics because of the indiscriminate use of these drugs. any new drug that can be effective in the treatment of these resistant cases will be welcome. the efficacy of cefoxitin in the treatment of twenty ...19852994436
urinary tract pathogens common amongst the inhabitants of a state capital, south west nigeria.in the course of a survey of urine samples collected over a period of 12 months from male and female patients of different socio-economic backgrounds in ibadan, esch. coli, klebsiella spp. pseudomonas aeruginosa, proteus spp., staphylococcus aureus and candida albicans were the most common pathogens isolated. the bacteria were commonly sensitive to the cephalosporins, kanamycin, ampicillin and cotrimoxazole in decreasing order of sensitivity.19863557825
urinary tract pathogens and antimicrobial sensitivity patterns in children in ibadan, nigeria.a study of bacterial organisms isolated from 65 nigerian children who had urinary tract infection (uti) is reported. the predominant isolate in both inpatients and outpatients was klebsiella species which accounted for 52.8% of cases. escherichia coli, pseudomonas spp and proteus spp accounted for 25.0%, 15.3% and 5.5% of isolates, respectively. all isolates were poorly sensitive to the common first-line drugs used in uti in our environment, namely, cotrimoxazole and ampicillin, but exhibited go ...19947880087
pattern of gram negative rods bacteraemia in diabetic patients in ibadan, nigeria.in a study of 100 patients in ibadan between july and december 1995 to evaluate bacteraemia due to gram-negative bacilli, 64% were culture positive, 44 (68.8%) of these yielded gram-negative rods. the isolates were klebsiella species (43.2%), escherichia coli (27.3%), pseudomonas aeruginosa (13.6%), proteus species (11.4%) and bacteroides melaninogenious (4.15%) by standard bacteriological methods. antimicrobial sensitivity results suggested ofloxacin or ceftriaxone with metronidazole as empiric ...200011713990
bacterial agents of discharging ears and antimicrobial sensitivity patterns in children in ibadan, nigeria.bacteriological studies were carried out on ear swabs from 361 cases of children with discharging ears at the microbiology department of the university college hospital, ibadan between march 1995 and february 1997. 308 (85.3%) had positive cultures. 78.6% of these yielded one isolate, 19.2% yielded two isolates while 2.2% had three isolates. pseudomonas spp. was the predominant agent of csom and asom. this was followed by staphylococcus aureus. other commonly isolated organisms were proteus and ...200111768012
pathogenic intestinal parasites and bacterial agents in solid wastes.to determine the profile of potentially pathogenic enteric parasites and bacterial agents in municipal refuse dumps in ibadan, nigeria.200212630495
aetiological agents, clinical features and outcome of septicaemia in infants in ibadan.the present study sought to determine the prevalence, clinical features and bacterial aetiological agents of septicaemia in post-neonatal infants (age 1-12 months) presenting with fever at the university college hospital, ibadan, nigeria.200312769303
comparative in-vitro activities of commonly available quinolones and other antibiotics on bacterial isolates in ibadan, nigeria.the 4-quinolones, many of which are now available in nigeria under different trade names, have a broad spectrum of activity. an evaluation is made of the comparative in-vitro activities of these quinolones and other antibiotics against 125 strains of bacteria commonly isolated from clinical specimens in university college hospital, ibadan, by using the stroke's disc sensitivity method, and mic estimation. the quinolones showed greater activity than the cephalosprins against klebsiella spp., prot ...200114510147
antimicrobial sensitivity pattern of organisms causing urinary tract infection in children with sickle cell anaemia in ibadan, nigeria.as part of a larger project on childhood urinary tract infection, antimicrobial sensitivity tests were carried out on the bacterial isolates from the urine of febrile children seen at the university college hospital, ibadan, nigeria.200314529216
bacteriology of non-surgical wound infections in ibadan, nigeria.previous studies done on wound infections in this environment had been mostly on the surgical variety rather than the non-surgical. however,few studies available on the non-surgical type have indicated that changes do occur in the pattern and antibiogram of the bacterial isolates of these non-surgical wound infections. this study was therefore designed to investigate the bacteriology of non-surgical wound infections in this environment. a retrospective review of seven hundred and fifty four case ...200818982819
asymptomatic bacteriuria among hiv positive pregnant women.the prognostic significance of asymptomatic bacteriuria resides in the observation that the prevalence is, relatively, high in persons with certain medical conditions, such as diabetes mellitus and pregnancy. this prevalence might, even, be higher in patients with human immunodeficiency virus infection. hence, this study set out to determine the prevalence of asymptomatic bacteriuria among symptom free and newly enrolled hiv infected pregnant women attending pmtct unit of antiretroviral clinic o ...201021178431
antibiotic susceptibility pattern of urinary tract pathogens in ibadan, nigeria.urinary tract infections (uti) affect all age groups and occur in both hospitalized and non-hospitalized individuals and have serious impact on the socioeconomic life of the individual and the society, and also account for a large proportion of antibacterial drug consumption. treatment failure has been attributed to increasing resistance to common antibiotics, but there is paucity of data from this part of nigeria. this prospective study was carried out to determine the prevalence and antibiotic ...201021416786
urinary pathogens and drug susceptibility patterns of urinary tract infections among antenatal clinic attendees in ibadan, nigeria.aim:  to determine the bacterial agents involved in urinary tract infections in pregnant women and their antibiotic susceptibility patterns in ibadan, nigeria. methods:  all consenting subjects who attended antenatal clinics of the university college hospital and adeoyo maternity hospital, ibadan, nigeria, from 1 april 2007 and 30 march 2009 were interviewed to obtain demographic and pregnancy health data. mid-stream urine samples obtained were processed by standard methods. confirmed bacterial ...201121917070
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