[the ratios and kinds of clinical bacteria isolated in taiwan's large-size hospitals].the prevalence of clinical bacteria, as isolated from linko chang-gung memorial hospital (2,300 beds) in the period january 1985 to december 1986 and from taipei veterans general hospital (2,300 beds) during the period january 1986 to december 1986, was analyzed with the following findings: (i) the isolation ratio of anaerobic and aerobic or facultative bactria during the period of investigation were 7.8% (5,513/70,799) and 92.2% (65,286/70,799), respectively. (ii) of the total aerobic or facult ...19892791722
classification, pathogenicity, and drug susceptibility of hemolytic gram-negative bacteria isolated from sick or dead chickens.fifteen hemolytic gram-negative bacteria were isolated from the respiratory tracts of sick birds suffering from a long-lasting respiratory syndrome or from the bone marrow of dead birds distributed in the southern part of taiwan. these were classified as pseudomonas aeruginosa (10 isolates), pseudomonas fluorescens (2 isolates), pseudomonas stutzeri (1 isolate), pasteurella haemolytica (1 isolate), and proteus morganii (1 isolate). each isolate was inoculated intraperitoneally into one group of ...19938452510
the prognostic factors of adult gram-negative bacillary meningitis.seventy-seven patients with gram-negative bacillary meningitis (gnbm), 57 males and 20 females, aged 17-86 years, were identified at kaohsiung chang gung memorial hospital, over an 11-year period. fifty-four infections were community-acquired, and 23 were nosocomial; 49 were spontaneous and 28 occurred after head surgery or neurosurgery. the organisms most frequently involved were klebsiella pneumoniae, pseudomonas aeruginosa, escherichia coli, and acinetobacter. rarer pathogens included citroba ...19989777518
emerging fluoroquinolone-resistance for common clinically important gram-negative bacteria in taiwan.the in vitro antimicrobial activity of the three most commonly used fluoroquinolones (norfloxacin, ofloxacin and ciprofloxacin) was measured for 2235 isolates of seven common pathogenic gram-negative bacteria. collected from a major teaching hospital in taiwan during the years 1985-86, 1989-90, and 1996-97, the samples were evaluated using the agar dilution method. the overall susceptibility to fluoroquinolones has decreased rapidly after the wide use of these antimicrobial agents. isolates of e ...200212088622
histamine-related hygienic qualities and bacteria found in popular commercial scombroid fish fillets in determine the histamine-related hygienic qualities and bacteria of scombroid fish fillets sold in traditional retail markets, 61 samples were collected from northern and southern taiwan. it was found that the content of volatile base nitrogen in most samples was below 25 mg/100 g, which is the regulatory level in taiwan. the ratio of unacceptable samples/total samples for aerobic plate count and escherichia coli was 100% and 15% in northern samples and 100% and 20% in southern samples, respec ...200414968980
the status of antimicrobial resistance in taiwan among gram-negative pathogens: the taiwan surveillance of antimicrobial resistance (tsar) program, a nationwide surveillance of antimicrobial resistance (taiwan surveillance of antimicrobial resistance, tsar), isolates were collected from 21 medical centers and regional hospitals throughout taiwan over a three-month period in 2000 (tsar ii). this report summarizes susceptibility data of 7 common gram-negative bacilli (escherichia coli, klebsiella pneumoniae, serratia marcescens, proteus mirabilis, enterobacter cloacae, pseudomonas aeruginosa, and acinetobacter baumannii) in the tsar ii col ...200415023432
cockroaches as potential vectors of nosocomial determine the possible role of cockroaches in the epidemiology of nosocomial infections.200415566034
isolation of bacteria with antibiotic resistance from household cockroaches (periplaneta americana and blattella germanica).cockroaches may harbor and disseminate microorganisms to the environment. in this study, periplaneta americana and blattella germanica were collected from 40 households in kaohsiung city and kaohsiung county, taiwan. cockroach infestation was found in 50% of the studied households and 226 cockroaches (123 p. americana and 103 b. germanica) collected by trapping. p. americana was more often found in the kitchen (70.7%) whereas b. germanica in the storage room (51.5%) and kitchen (36.9%). there wa ...200515716054
relationships between antimicrobial use and antimicrobial resistance in gram-negative bacteria causing nosocomial infections from 1991-2003 at a university hospital in taiwan.this study was conducted to evaluate the relationship between antimicrobial resistance and antimicrobial use in a university hospital in taiwan. disk susceptibility data of escherichia coli, klebsiella pneumoniae, enterobacter cloacae, serratia marcescens, proteus spp., pseudomonas aeruginosa, acinetobacter spp., stenotrophomonas maltophilia and other non-fermentative gram-negative bacilli causing nosocomial infections were evaluated. data on annual patient-days and annual consumption (defined d ...200516280243
in vitro activities of tigecycline, ertapenem, isepamicin, and other antimicrobial agents against clinically isolated organisms in taiwan.this study evaluated the in vitro activities of tigecycline, ertapenem, isepamicin, and other comparators against 861 bacterial isolates recovered from patients treated in three major teaching hospitals in 2003. mics to antimicrobial agents were determined by the agar dilution method. high rates of oxacillin resistance (58%) in staphylococcus aureus (60 isolates), and vancomycin resistance (21%) and quinupristin-dalfopristin non-susceptibility (39%) in enterococcus faecium (34 isolates) were fou ...200516359192
antimicrobial resistance of bacterial isolates from respiratory care wards in taiwan: a horizontal surveillance study.a horizontal surveillance study was conducted to identify common bacteria and mycobacteria from 611 respiratory aspirates and 165 urinary samples from 611 patients hospitalised at 17 respiratory care wards (rcws) in taiwan. some major resistance phenotypes, including methicillin-resistant staphylococcus aureus (mrsa), extended-spectrum beta-lactamase (esbl)-producing escherichia coli, klebsiella pneumoniae and proteus mirabilis, and multidrug-resistant pseudomonas aeruginosa (mdr-pa) and acineto ...200818358701
nationwide surveillance in taiwan of the in-vitro activity of tigecycline against clinical isolates of extended-spectrum beta-lactamase-producing enterobacteriaceae.tigecycline in-vitro surveillance in taiwan (tist), initiated in 2006, is a nationwide surveillance programme designed to monitor longitudinally the in-vitro activity of tigecycline against commonly encountered resistant bacteria. this study compared the in-vitro activity of tigecycline against clinical isolates of resistant gram-negative bacteria determined by the broth microdilution and etest methods. a total of 622 isolates were collected from patients treated at 20 teaching hospitals. tigecy ...200819013351
correlation between antibiotic consumption and resistance of gram-negative bacteria causing healthcare-associated infections at a university hospital in taiwan from 2000 to 2009.this study investigated the correlation between antibiotic consumption and antimicrobial resistance in gram-negative bacteria causing healthcare-associated infections at a university hospital in taiwan from 2000 to 2009.201121436153
microbial isolation and emergence of antimicrobial resistance associated with tigecycline usage.background: with the increasing experience of tigecycline usage, its ecological impact on microorganisms raises concerns but remains unknown. we aimed to analyze the difference in microorganisms isolated before, during, and after tigecycline usage and their susceptibility to antimicrobial agents. methods: between july 2008 and august 2009, 66 patients who received tigecycline monotherapy for more than 2 days at a taiwan medical center were enrolled. antimicrobial susceptibility testing was perfo ...201121524975
comparison of aminoglycoside resistance patterns in japan, formosa, and korea, chile, and the united states.the resistance mechanisms of more than 2,000 aminoglycoside-resistant gram-negative aerobic bacteria were estimated by a method that assigned a biochemical mechanism based on susceptibility to selected aminoglycosides. strains from hospitals in japan, formosa, and korea (the far east) were compared with strains from chile and the united states. of the strains from chile, 90% had an aminoglycoside resistance pattern indicative of the 3-n-acetyltransferase [aac(3)-v] enzyme. of the strains from th ...19853914858
clinical observations of scrub typhus on penghu (the pescadores islands).between may and september 1973, 68 cases of scrub typhus in chinese military personnel on the pescadores islands were studied. the common symptoms and signs were fever, chills, headache, eschar, myalgia, and lymph node enlargement. most eschars were located in the axilla, waist, groin and genitals, and neck. these lesions were painless and not noticed by the patients themselves. regional lymph node enlargement at the site of eschar drainage was common. relative bradycardia with fever was observe ...19751179479
clinical, immunological and genetic features in taiwanese patients with the phenotype of hyper-immunoglobulin e recurrent infection syndromes (hies).hyper-immunoglobulin e recurrent infection syndromes (hies) have distinct features, with identified associated mutations of stat3, tyk2, and dock8. among 197 taiwanese patients with primary immunodeficiency on a referral-base of over 23 million inhabitants, stat3 (r382w and q469r) and dock8 mutations (exon 1-9 deletion) were identified in two patients each from six ad-hies and five ar-hies patients, respectively. aside from decreased th17 and memory b cells, characteristic facies and pneumatocel ...201121324546
clinical aspects and genetic analysis of taiwanese patients with the phenotype of hyper-immunoglobulin e recurrent infection syndromes (hies).hyper-immunoglobulin e recurrent infection syndromes (hies) has characteristic features and identified mutations. this study investigated clinical features and causal candidate mutations in taiwanese patients with the hies phenotype on referral base over 23 million inhabitants.201021120687
comparative study on characteristics of azo dye decolorization by indigenous decolorizers.this study provides a first attempt to explore indigenous strains with excellent decolorization capability from the most biodiverse region in taiwan for dye-bearing wastewater treatment. bacterial isolates were obtained via serial selections under selection pressure of the fungicide nystatin and model textile dye(s). according to profiles of protein expression and pcr-augmented 16s rrna gene analyses for strain identification, >99% of nucleotide sequences in isolated strains were identical to ty ...201019944603
changing trend in antimicrobial resistance of pediatric uropathogens in taiwan.there is growing concern regarding antimicrobial resistance worldwide, particularly of escherichia coli, and the first choice of an antimicrobial agent for empiric treatment of pediatric urinary tract infection (uti) is not well established.200819067894
nationwide surveillance of antimicrobial resistance among enterobacteriaceae in intensive care units in determine the antimicrobial resistance profiles among clinical isolates of enterobacteriaceae in taiwanese intensive care units (icus), a national surveillance of antibiotic resistance among important enterobacteriaceae was conducted from september 2005 through november 2005 at the icus of ten major teaching hospitals in taiwan. a total of 574 enterobacteriaceae isolates recovered from various clinical samples of our icu patients were submitted for in vitro test. minimum inhibitory concentrat ...200918716805
fournier's gangrene: ten-year experience in a medical center in northern taiwan.fournier's gangrene is a life-threatening infection. the mortality is still high despite the rapid advancement of modern intensive care and surgical technique. in this study, we present our institution's recent experience with a large series of patients with fournier's gangrene.200718087630
prevalence of extended-spectrum beta-lactamases in proteus mirabilis in a taiwanese university hospital, 1999 to 2005: identification of a novel ctx-m enzyme (ctx-m-66).a total of 1574 nonduplicate proteus mirabilis isolates collected at a taiwanese hospital during 1999 to 2005 were analyzed for production of extended-spectrum beta-lactamases (esbls). forty-four esbl-producing isolates including 22 ctx-m-14, 18 ctx-m-3, 2 ctx-m-24, and 2 ctx-m-66 producers were detected, and the proportion of esbl producers increased from 0.7% in 1999 to approximately 6% after 2002. ctx-m-66 is a novel variant of ctx-m esbls that differs from ctx-m-3 by a ser to asn change at a ...200817913434
extended-spectrum beta-lactamases in taiwan: epidemiology, detection, treatment and infection control.extended-spectrum beta-lactamases (esbls) efficiently hydrolyze extended-spectrum beta-lactams such as cefotaxime, ceftriaxone, ceftazidime, and aztreonam. esbls are most often plasmid-mediated. in taiwan, the prevalence of esbls in bacteria has risen, ranging from 8.5 to 29.8% in klebsiella pneumoniae and 1.5 to 16.7% in escherichia coli isolates. the most prevalent types of esbls are shv-5, shv-12, ctx-m-3, and ctx-m-14 in isolates of k. pneumoniae and e. coli, with differences between institu ...200616926972
dissemination of proteus mirabilis isolates harboring ctx-m-14 and ctx-m-3 beta-lactamases at 2 hospitals in taiwan.from february to june 2003, 111 clinical isolates of proteus mirabilis were mainly isolated from patients with respiratory or urinary tract infections hospitalized at 3 district hospitals (a, b, c) in central taiwan. among them, 34 (30.6%) strains, isolated within 2 hospitals (a and b), exhibited nonsusceptibility to cefotaxime with significant reduction of mic (> or = 3 log2 dilution) by the effect of clavulanic acid, which confirmed the phenotype of extended-spectrum beta-lactamases (esbls). t ...200616406185
childhood urinary tract infection: a clinical analysis of 597 cases.objectives of study: to gain new insights into the epidemiology, genitourinary (gu) tract anomalies, etiologies, susceptibility of urinary pathogens to antibiotics in children with urinary tract infection (uti) during the past decade in taiwan.200415868848
characteristics of neonatal bacterial meningitis in a teaching hospital in taiwan from 1984-1997.during the period from 1984 to 1997, 85 bacterial meningitis neonates with positive cerebrospinal fluid cultures were treated. the ages of these patients ranged from 1 to 28 days. the male to female ratio was 1.7 to 1. the most common causative agent was group b beta-hemolytic streptococci (gbs, 31.8%), followed by escherichia coli (20%), proteus mirabilis (7.1%), enterobacter cloacae (5.9%), other streptococci excluding streptococcus pneumoniae (5.9%), chryseobacterium meningosepticum (5.9%), e ...200010917879
[urinary tract infections and microbiological characteristics of proteus penneri isolated in taiwan].proteus penneri has been reported to be involved in urinary tract infections and calculi formation. we analyzed 2,265 positive urine cultures from patients hospitalized in taipei veterans general hospital, taiwan and found that 47 patients (2.1%) were infected by p. penneri. most of the patients were male with age over sixty and had been treated with various kinds of antibiotics. most of the patient's urine were collected by catheter. they were alkaline (ph 8.0) and contained amorphous phosphate ...19873652782
urolithiasis in children.a retrospective study of childhood urolithiasis was performed from july 1978 to december 1989 in the national taiwan university hospital. during the eleven years, fourteen patients aged from 1 to 16 years were enrolled. the male to female ratio was 10:4, but no sex predilection was found in seven children with bladder stone(s) (m:f = 4:3), hematuria and pyuria were the commonest symptoms and signs. bladder stone was the most frequently encountered stone while renal stone was the second. the unde ...19912063681
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