Publications

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epidemiologic patterns of acute diarrhea and endemic shigella infections in children in a poor periurban setting in santiago, chile.to prepare a field site for evaluating preventive interventions against endemic shigellosis, the authors followed prospectively a cohort of 360 children (90 each of children aged 0-11, 12-23, 24-35, and 36-47 months) in santa julia, a low socioeconomic area in santiago, chile, from november 1986 through april 1989 with twice weekly household visits for diarrheal disease; infants replaced children who reached 60 months of age. coprocultures on 2 consecutive days from children with diarrhea and fr ...19911951266
enteropathogens associated with acute diarrhea in hospitalized infants.thirty-five infants of low socioeconomic status who were living in urban santiago were hospitalized for acute diarrhea were prospectively evaluated for the presence of enteropathogens associated with the episode. some degree of malnutrition was evident in 20 infants (57.1%); 15 of these (75%) were under 6 months of age. mean duration of the hospital stay was 11.8 days for well-nourished patients and 15.7 days for the malnourished patients. one or more enteropathogens were found in 60% of the cas ...19863007718
typhoid fever in santiago, chile: a study of household contacts of pediatric patients.we obtained clinical, epidemiological, and laboratory data (including three stool cultures) from 155 (96%) of 161 household contacts of 24 patients less than 16 years old with culture-confirmed typhoid fever; these 24 patients represented approximately 40% of such patients seen in three hospitals in santiago during a 12-week period. a chronic typhoid carrier was identified in only one household, with concurrent or secondary cases seen in two other households. when index cases were matched with h ...19846507731
chronic iron intake and diarrhoeal disease in infants. a field study in a less-developed country.the effect of chronic iron intake on diarrhoeal disease was evaluated in children in a community of low socio-economic stratum in santiago, chile. children were incorporated into each of two consecutive cohorts; each cohort was divided into two groups, one receiving iron-enriched milk (12 mg/l) (monthly average = 70 children) and the other a control milk (1 mg/l) (monthly average = 83 children), and each cohort was followed up for 6 months. the incidence of diarrhoea was higher among the iron-su ...19938319667
[antimicrobial multiresistance of shigella sp strains in a semi rural community of northern santiago].appropriate antimicrobial therapy shortens the duration of shigellosis and significantly reduces the risk of transmission. shigella strains resistant to common antimicrobials have increased during the past years, determining the need for a periodic surveillance, to guide effective therapy.199810349160
population-based study of the incidence of shigella diarrhea and causative serotypes in santiago, chile.shigella is an important cause of diarrheal disease in children in developing countries. the increasing prevalence of antibiotic-resistant strains has stimulated interest in the use of multivalent shigella vaccines. because shigella vaccines under development are based on eliciting immunity to o antigens, monitoring the distribution of serotypes in defined target populations is critical. we initiated health center-based surveillance in a poor semirural community in colina, santiago (7489 childre ...199910391178
[epidemiological situation of foodborne diseases in santiago, chile in 1999-2000].foodborne diseases are becoming an important cause of morbidity in chile. in the metropolitan region of chile, the environmental health service started a surveillance program for foodborne diseases in 1994. in 2000, this program was complemented with an etiologic study of individuals involved in outbreaks.200212143269
surveillance for antimicrobial resistance profiles among shigella species isolated from a semirural community in the northern administrative area of santiago, chile.variations in antibiotic resistance patterns were studied among 178 shigella strains isolated from 1997 to 2001 in children less than five years of age with acute diarrhea from colina, a semi-rural community in santiago, chile. the minimal inhibitory concentration of several commonly used antibiotics was determined by the agar dilution method. shigella strains showed high rates of resistance to ampicillin (82%), cotrimoxazole (65%), tetracycline (53%), and chloramphenicol (49%). furthermore, 51% ...200515964975
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