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[multilocus sequence-typing for characterization of moscow strains of haemophilus influenzae type b].haemophilius influenzae, type b (hib) bacteria, were genotyped by multilocus sequence typing (mlst) using 5 loci (adk, fuck, mdh, pgi, reca). 42 moscow hib strains (including 38 isolates form cerebrospinal fluid of children, who had purulent meningitis in 1999-2001, and 4 strains isolated from healthy carriers of hib), as well as 2 strains from yekaterinburg were studied. in mlst a strain is characterized, by alleles and their combinations (an allele profile) referred to also as sequence-type (s ...200312800772
[moraxella catarrhalis in chronic and relapsing respiratory tract infections in children].examination of 700 children with chronic and relapsing respiratory tract infections showed that during the period from 1996 to 2003 moraxella catarrhalis strains were isolated from the sputum of 5.5-9.7% of the patients. the frequency of the emergence was the third after haemophilus influenzae and streptococcus pneumoniae. in healthy children m. catarrhalis was isolated in 2.7% of the cases. the most frequent detection of m. catarrhalis was stated in children under 1 year (4.5%). the antibiotic ...200415727145
[genetic characteristic of haemophilus influenzae type b strains isolated in russian regions].genotyping of hib strains isolated in regions of russia as well as characterization of genetic relations of typed strains with strains isolated in other areas.201020218340
[genetic characteristics of haemophilus influenzae type b isolated from children with bacterial meningitis in moscow in 2007-2009].genetic characterization of 37 strains and csf samples containing dna of haemophilus influenzae type b isolated in moscow during 2007-2009.201020795380
[characteristics of fauces microflora in children treated in intensive care units].characteristic features of fauces aerobic microflora in children treated in intensive care units (icu) were analysed. for comparison fauces microflora in children outpatients and in children patients from general surgical units was investigated. a retrospective analysis of all the smears without exception for 2 years (a total of 2120) revealed a direct dependence of the changes in the fauces microflora composition on the patient condition and the antibiotic load. it was shown that the fauces ind ...19989777101
[the characteristics of suppurative meningitis morbidity caused by streptococcus pneumoniae and haemophilus influenza type b].of the 1,018 patients with purulent bacterial meningitis, hospitalized at the 2nd clinical infectious hospital in moscow during the period of 1980-1987, the diagnosis was confirmed in 54.7%; of these, meningitis of pneumococcal etiology was established in 44.8% and meningitis caused by h. influenzae, type b, in 23.8% of the patients. in meningitis of pneumococcal etiology high risk groups included mainly adults, especially those over 50 years, and children under 3 years of age. in meningitis of ...19902330778
[genetic relationships of moscow and foreign strains of haemophilus influenzae, serotype b].46 haemophilus influenzae strains of serotype b, isolated on the territory of moscow and compared with foreign strains, were characterized by the method of multilocus sequencing-typing. among the strains circulating in moscow 10 variants of sequence-types were observed; of these, only one variant (ct-6) had been described earlier. the analysis of the data revealed that the strains under study were distributed in two clonal complexes; the overwhelming majority of the strains belonged to sequence- ...200617163132
[etiology and rational therapy of severe otitis media purulenta acuta in children].etiology and antibiotic susceptibility of the pathogens of otitis media purulenta acuta in children was studied within 2000-2005. a total of 161 children at the age of 1 to 14 years were examined. the middle ear discharge collected during paracentosis (79.5%) or spontaneous perforation of the tympanic membrane (20.5%) was used in the bacteriological tests. the microflora growth in the culture was detected in 80% of the cases. the leading pathogen was streptococcus pyogenes (47.5%), the part of s ...200616878389
[haemophilus influenzae antibiotic resistant strains isolated in moscow in 2002-2004].the results of 3-year observation on emergence of h. influenzae antibiotic resistant strains in moscow are summarized. the study included 566 strains isolated from patients in 2002-2004. the susceptibility was determined by the 2-fold microdilution method on the haemophilus test medium. the percentage of the resistant strains isolated in 2002, 2003 and 2004 was the following: ampicillin --4.9, 3.2 and 3.6%, tetracycline--3.3, 3.2 and 1.8% and co-trimoxazole--10.9, 20.9 and 20% respectively. the ...200416050495
economic evaluation of haemophilus influenzae type b vaccination in moscow, russian federation.to estimate the cost-effectiveness of providing haemophilus influenzae type b (hib) vaccine to children in moscow in routine immunization services.200616413949
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