Publications

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evaluation of multiplex real-time pcr for detection of haemophilus ducreyi, treponema pallidum, herpes simplex virus type 1 and 2 in the diagnosis of genital ulcer disease in the rakai district, uganda.to develop a real-time pcr assay that reliably and accurately detects the predominant sexually transmitted aetiological agents of genital ulcer disease (gud) (haemophilus ducreyi, treponema pallidum and herpes simplex virus type 1 (hsv-1) and type 2 (hsv-2)) and to assess the use of real-time pcr diagnostic testing in a rural african field site.200919066198
bacteraemia in homozygous sickle cell disease in africa: is pneumococcal prophylaxis justified?the high frequency of streptococcus pneumoniae as a cause of bacteraemia in homozygous sickle cell (ss) disease and its effective prevention has led to the routine use of pneumococcal prophylaxis in developed countries. the reported infrequency of this organism as a cause of bacteraemia in ss disease in africa raises questions on the epidemiology of bacterial infection and on the need for pneumococcal prophylaxis in that continent.200716531454
community-acquired pneumonia in ugandan adults: short-term parenteral ampicillin therapy for bacterial pneumonia.a hospital-based prospective study of 99 patients with community-acquired pneumonia (cap) was carried out in kampala, uganda. we evaluated microbiological etiologies, clinical features and effectiveness of short-term parenteral ampicillin followed by oral amoxicillin for these patients in relation to hiv-status. we demonstrated a very high prevalence (75%) of hiv-1 infection. no significant difference was observed with respect to age, gender, prior antibiotic usage, symptoms, laboratory data or ...200111442214
observations on the nasopharyngeal carriage of haemophilus influenzae type b in children in kampala, uganda.haemophilus influenzae type b was isolated from 4.5% of outpatient children living in various parts of kampala city and its surroundings. in contrast, this serotype was carried by up to 53% (average 29%) of 14 to 18 children living as a group in an orphanage. this finding indicates that the high carriage rate for this serotype demonstrated by turk (1963) in a group of orphanage infants in jamaica was not an isolated finding, and that it may be expected where large groups of children live togethe ...19705310719
the bacteriology of terminal pneumonia. an autopsy study in mulago hospital, kampala. 19685305917
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