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kuehneromycins a and b, two new biological active compounds from a tasmanian kuehneromyces sp. (strophariaceae, basidiomycetes).in a search for new inhibitors of rna-directed dna-polymerases kuehneromycin a (1) was isolated from fermentations of a tasmanian kuehneromyces species. its structure was elucidated by spectroscopic methods. kuehneromycin a (1) is a non-competitive inhibitor of avian myeloblastosis virus (ki 200 microm) and moloney murine leukemia virus (ki 40 microm) reverse transcriptases. the second compound, kuehneromycin b (2) is a strong inhibitor of platelet aggregation stimulated with different inducers. ...19957535532
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