| epidemiological studies of hemorrhagic fever with renal syndrome (hfrs) related virus infection among urban rats in hokkaido, japan. | seroepidemiological studies of hemorrhagic fever with renal syndrome (hfrs) virus infection were carried out among urban rats (rattus norvegicus and rattus rattus) and small field rodents in hokkaido, japan. an urban rat colony that was seropositive to sr-11 strain of hfrs virus (laboratory rat origin) was demonstrated in february 1983 at a dumping ground area of kami-iso town near hakodate port. an hfrs-related virus, named ki-262 strain, was isolated from the lung tissue of a seropositive rat ... | 1986 | 2871823 |
| evidence for the existence of puumula-related virus among clethrionomys rufocanus in hokkaido, japan. | we conducted field surveys of indigenous rodent species in hokkaido, japan from 1980 to 1993. serum samples were collected from 663 rodents, including clethrionomys rufocanus, apodemus speciosus, a. argenteus, and c. rutilus. antibody to hantavirus was determined by the protein g antibody assay. positive c. rufocanus were detected in seven of eight collection sites, but no antibody was detected in the remaining rodent species. to reveal the serotype of the circulating virus in c. rufocanus, anti ... | 1995 | 7573700 |
| epizootiological studies of hantavirus infection among urban rats in hokkaido, japan: evidences for the persistent infection from the sero-epizootiological surveys and antigenic characterizations of hantavirus isolates. | epizootiological studies of hantavirus infection among urban rats were carried out through the surveys repeated 11 times at the same dumping ground area in 1983 to 1988. a total of 279 rats (rattus norvegicus) were captured during the surveys. sero-positive animals to hantavirus strain sr-11 were detected in all the surveys. overall positive rate of rats 6 months old or more (94/128, 73.4%) was significantly higher than that of younger rats (23/151, 15.2%, x2 = 96.4, p < 0.001). therefore, age d ... | 1994 | 7911335 |
| genetic diversities of hantaviruses among rodents in hokkaido, japan and far east russia. | seroepizootiologic surveys among wild rodents were carried out in japan and far east russia in 1995 and 1996. seropositive animals were only identified in clethrionomys rufocanus (23/134) in hokkaido, japan. on the other hand, seropositives were identified in c. rufocanus (1/8), apodemus agrarius (2/66), apodemus spp. (2/26) and microtus fortis (3/22) in vladivostok, far east russia. total rna was isolated from lungs of seropositive animals and the s genome segments were amplified by pcr, cloned ... | 1999 | 10082393 |
| detection of hantaviral antibodies among patients with hepatitis of unknown etiology in japan. | hantaviral antibodies were detected in the sera from patients with hepatic disease of unknown etiology in japan by several different serological diagnostic methods. a total of 105 sera from diseased patients which were negative to a-g hepatitis virus infections in the tokyo area were tested. among them, 3 out of 73 sera from patients with chronic hepatic disease were positive to hantaviral antibody by enzyme-linked immunosorbent assay (elisa), indirect immunofluorescent antibody assay (ifa) and ... | 2000 | 10888353 |
| epidemiology and epizootiology of hantavirus infection in japan. | hantaviruses cause two severe human diseases: hemorrhagic fever with renal syndrome (hfrs) and hantavirus pulmonary syndrome (hps). various rodent species act as animal reservoirs for hantavirus. in japan, urban rat- (rattus norvegicus) and laboratory rat-derived human infections were reported during the 1960s and 1970s-1984, respectively. although no human cases of infection have been reported since 1984, infected urban rats have been found throughout japan, and infected grey red-backed voles ( ... | 2001 | 11544398 |
| modes of hantavirus transmission in a population of clethrionomys rufocanus bedfordiae inferred from mitochondrial and microsatellite dna analyses. | to elucidate the mode of transmission of puumala-related hantavirus in a population of gray red-backed voles, clethrionomys rufocanus bedfordiae, in hokkaido, japan, we analyzed the kin structure and dispersal patterns of individual voles using microsatellite and mitochondrial dna markers. siblings or dam/offsprings was identified within the population based on the relatedness calculation with the microsatellite data. the pairwise relatedness values obtained could reveal kinship among all vole i ... | 2004 | 15098108 |
| mode of infection of hokkaido virus (genus hantavirus) among grey red-backed voles, myodes rufocanus, in hokkaido, japan. | hokkaido virus (hokv) is a member of the genus hantavirus, in the family bunyaviridae. to investigate hokv infection in the host myodes rufocanus, the grey red-backed vole, 199 animals were captured at tobetsu (october 2004 and july 2005) and nakagawa (october 2004) in hokkaido, japan, for detection of antibody, antigen, and viral rna. in the surveys in tobetsu (2004) and nakagawa (2004), seropositive animals were detected at a frequency of 6.0% (5/84) and 10.4% (5/48), respectively. no seroposi ... | 2007 | 18037785 |
| an efficient in vivo method for the isolation of puumala virus in syrian hamsters and the characterization of the isolates from russia. | puumala virus (puuv) and other arvicolinae-borne hantaviruses are difficult to cultivate in cell culture. to isolate these hantaviruses efficiently, hantavirus nucleocapsid protein (np)-positive but seronegative wild rodents were selected by np-detection elisa. three of 68 myodes glareolus captured in samara, russia, were np-positive and seronegative. syrian hamsters were inoculated with lung homogenates from np-positive rodents for virus propagation. virus isolation in vitro was carried out by ... | 2010 | 21192975 |
| epizootiological and epidemiological study of hantavirus infection in japan. | epizootiological surveys on hantavirus infections in rodents were carried out in various areas of japan, including the four major islands of hokkaido, honshu, shikoku, and kyushu from 2000 to 2003. a total of 1,221 rodents and insectivores were captured. seropositive animals were found in apodemus (a.) speciosus (5/482, 1.0%), rattus (r.) norvegicus (4/364, 1.1%), r. rattus (3/45, 6.7%), and clethrionomys (c.) rufocanus (7/197, 3.6%). the partial s segment was amplified from one seropositive r. ... | 2004 | 15557742 |