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crossbyanols a-d, toxic brominated polyphenyl ethers from the hawai'ian bloom-forming cyanobacterium leptolyngbya crossbyana.periodically, the marine cyanobacterium leptolyngbya crossbyana forms extensive blooms on hawai'ian coral reefs and results in significant damage to the subtending corals. additionally, corals near mats of this cyanobacterium, but not directly overgrown, have been observed to undergo bleaching. therefore, samples of this cyanobacterium were chemically investigated for bioactive secondary metabolites that might underlie this toxicity phenomenon. (1)h nmr spectroscopy-guided fractionation led to t ...201020170122
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