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long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in staphylococcus aureus in danish cf patients.since 2001, long-term, low-dose azithromycin treatment has been used for cf patients chronically infected with pseudomonas aeruginosa in the copenhagen cf centre. our study investigates changes in incidence of colonization with staphylococcus aureus, streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis and changes in macrolide sensitivity in these microorganisms during azithromycin treatment.200918849202
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