Publications

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correspondence: effect of liver fluke on wool production in welsh mountain sheep. 1976945633
some observations on the epidemiology of fascioliasis in relation to the timing of molluscicide applications in the control of the disease. 19715102169
fascioliasis--a large outbreak.forty-four cases of liver fluke infestation (fascioliasis hepatica) were diagnosed near chepstow, monmouthshire, in 1968. intramuscular emetine hydrochloride and oral chloroquine given to the adults and children, respectively, were well tolerated. assessment by repeated stool examination, complement fixation and liver function tests, and full blood counts indicated that treatment had been effective in most cases. it is recommended that both the growth and the sale of watercress should be strictl ...19705454343
outbreak of liver fluke infestation. 19695787291
report on the working party on liver-fluke in wales. 19695813271
soil type and the distribution of lymnaea truncatula.habitat distribution of the snail lymnea truncatula, the intermediate host of the liver fluke fasciola hepatica, was related to a soil map in a part of dyfed in south wales. there was a close association with wet soils in general but, within these areas, habitats were concentrated in very wet localities of restricted size, such as ditches and seepages. vegetation characteristic of these habitats is described. soil maps could be a useful tool for the veterinary officer, agricultural adviser and r ...19846719774
prevalence of fasciola hepatica in dairy herds in england and wales measured with an elisa applied to bulk-tank milk.an elisa developed to diagnose fasciola hepatica infection in cattle by detecting serum antibodies was adapted and validated for use with samples of bulk-tank milk. the prevalence of the infection in 61 dairy herds was established by using serum antibody levels or faecal egg counts measured in a proportion of the cows in each herd. the correlation between the results of the elisa and the herd seroprevalence was 0.83. using a cut-off value of 27 per cent positive, the bulk-tank elisa identified h ...200515937238
the development of linear regression models using environmental variables to explain the spatial distribution of fasciola hepatica infection in dairy herds in england and wales.fasciolosis caused by fasciola hepatica is a major cause of economic loss to the agricultural community worldwide as a result of morbidity and mortality in livestock. spatial models developed with the aid of geographic information systems (gis) can be used to develop risk maps for fasciolosis for use in the formulation of disease control programmes. here we investigate the spatial epidemiology of f. hepatica in dairy herds in england and wales and develop linear regression models to explain obse ...201020227416
seroprevalence and spatial distribution of fasciola hepatica-infected dairy herds in england and wales.the seroprevalence of fasciola hepatica infection in a population of commercial dairy herds in england and wales was estimated using an elisa that detected antibodies to f hepatica in bulk tank milk. a total of 3130 milk samples, obtained as convenience samples from two commercial milk-testing laboratories, were tested during the winter of 2006/07. herds considered to be seropositive were categorised as low positive, medium positive or high positive. a geospatial map was drawn to show the distri ...201020472872
high incidence of liver fluke in cattle herds in england and wales. 201020643883
predicting impacts of climate change on fasciola hepatica risk.fasciola hepatica (liver fluke) is a physically and economically devastating parasitic trematode whose rise in recent years has been attributed to climate change. climate has an impact on the free-living stages of the parasite and its intermediate host lymnaea truncatula, with the interactions between rainfall and temperature having the greatest influence on transmission efficacy. there have been a number of short term climate driven forecasts developed to predict the following season's infectio ...201121249228
faecal egg count reduction test to detect lack of efficacy of triclabendazole. 201021257517
fasciola hepatica is associated with the failure to detect bovine tuberculosis in dairy cattle.bovine tuberculosis (btb) is a significant and intractable disease of cattle caused by mycobacterium bovis. in the united kingdom, despite an aggressive eradication programme, the prevalence of btb is increasing with an unexplained, exponential rise in cases year on year. here we show in a study involving 3,026 dairy herds in england and wales that there is a significant negative association between exposure to the common, ubiquitous helminth parasite, fasciola hepatica and diagnosis of btb. the ...201222617293
ostertagia spp., rumen fluke and liver fluke single- and poly-infections in cattle: an abattoir study of prevalence and production impacts in england and wales.this study aims at investigating the occurrence, risk factors and production impacts on beef carcass parameters of three of the most important cattle helminth infections in england and wales. abomasa, reticulorumens and livers from healthy cattle were collected and examined post-mortem quarterly over a one year period in an abattoir in south-west england. specific viscera from 974 cattle were collected, examined and scored for ostertagia spp., adult rumen fluke and liver fluke lesions/presence. ...201627664452
composite faecal egg count reduction test to detect resistance to triclabendazole in fasciola hepatica.a faecal egg count reduction test, using composite samples, was developed in order to assess the efficacy of the flukicide, triclabendazole (tcbz) on commercial sheep farms in england and wales. first, a comparison between individual counts and composite counts was conducted using sheep on two farms with different levels of infection. faecal samples were collected from 50 sheep on each farm at the time of tcbz treatment and 21 days later. the results showed that a composite fluke egg coun ...201222791519
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