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patellamide a and c biosynthesis by a microcin-like pathway in prochloron didemni, the cyanobacterial symbiont of lissoclinum patella.prochloron spp. are obligate cyanobacterial symbionts of many didemnid family ascidians. it has been proposed that the cyclic peptides of the patellamide class found in didemnid extracts are synthesized by prochloron spp., but studies in which host and symbiont cells are separated and chemically analyzed to identify the biosynthetic source have yielded inconclusive results. as part of the prochloron didemni sequencing project, we identified patellamide biosynthetic genes and confirmed their func ...200515883371
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