Publications

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identification of variant abc-transporter genes among onchocerca volvulus collected from ivermectin-treated and untreated patients in ghana, west africa.treatment with ivermectin (ivm) is known to cause a loss of polymorphism at certain loci of the beta-tubulin, gamma-aminobutyric-acid-receptor, glutamate-gated-chloride-channel and atp-binding-cassette (abc) transporter genes of ivm-resistant haemonchus contortus. the genetic variation of four abc-transporter homologues from onchocerca volvulus was therefore investigated, to determine if any change in genetic polymorphism occurs in these genes following repeated treatment with ivm. samples were ...200415228718
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