development of multiplex pcr assays based on the 16s-23s rrna internal transcribed spacer for the detection of clinically relevant nontuberculous accelerate the identification and differentiation of clinically relevant nontuberculous mycobacteria (ntm) with two sets of multiplex pcr (mpcr) targeting the 16s-23s rrna internal transcribed spacer (its) region for timely patient management.201121395629
nontuberculous mycobacterial disease of the lungs in singapore.information on lung disease due to nontuberculous mycobacteria (ntm) is lacking in singapore. a review of the records at the central tuberculosis laboratory up to the end of 1988 showed that 23 patients seen between 1976 to 1988 inclusive had cultures which were repeatedly positive for ntm. of the 23 cases analyzed, 15 were found to have lung disease which could be attributed to ntm. there were 9 males and 6 females with a male to female ratio of 1.5:1. the patients were either middle aged or el ...19921455269
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