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viral pathogens including human metapneumovirus are the primary cause of febrile respiratory illness in hiv-infected adults receiving antiretroviral therapy.to determine the spectrum of pathogens causing acute febrile respiratory illness in human immunodeficiency virus (hiv)-infected adults, we re-analyzed data from a prospective surveillance study involving 50 outpatients (90% of whom received highly active antiretroviral therapy). nasopharyngeal samples were tested for 23 respiratory viruses by multiplex reverse-transcriptase polymerase chain reaction (pcr) and for atypical bacteria by pcr. sputum cultures and serological testing were performed. v ...201019951142
human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease.we tested nasopharyngeal aspirate specimens by real-time polymerase chain reaction assays and paired serum samples by enzyme-linked immunosorbent assays. acute human metapneumovirus infections were identified in 6 (4.1%) of 145 adult patients who presented to the emergency department for pneumonia or acute exacerbation of chronic obstructive pulmonary disease during 2 winter/spring seasons in quebec, canada.200516028158
characterization of human metapneumoviruses isolated from patients in north america.human metapneumovirus (hmpv) was recently identified in the netherlands and was linked to acute respiratory tract illness. in this study, 11 isolates from 10 patients with respiratory disease from quebec, canada, were tested by a reverse-transcriptase polymerase chain reaction based on the fusion protein gene. identified sequences were consistent with hmpv. the patients were 2 months to 87 years of age (median age, 58 years) and presented with acute respiratory tract illness during the winter se ...200212023774
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