| non-travel-associated hepatitis e in england and wales: demographic, clinical, and molecular epidemiological characteristics. | between 1996 and 2003, 186 cases of hepatitis e were serologically diagnosed. of these, 17 (9%) were not associated with recent travel abroad. patients were >55 years old (range, 56-82 years old) and tended to be male (76%). two patients presented with fulminant hepatitis. a total of 129 (69%) cases were associated with recent travel to countries where hepatitis e virus (hev) is hyperendemic. compared with patients with travel-associated disease, patients with non-travel-associated disease were ... | 2005 | 16136458 |
| indigenous hepatitis e virus infection in england and wales. | | 2006 | 16793820 |
| hepatitis e in england and wales. | in 2005, 329 cases of hepatitis e virus infection were confirmed in england and wales; 33 were confirmed indigenous infections, and a further 67 were estimated to be indigenous infections. hepatitis e should be considered in the investigation of patients with hepatitis even if they have no history of travel. | 2008 | 18258100 |
| clinical characteristics of hepatitis e in a "non-endemic" population. | hepatitis e virus (hev) is a ribonucleic acid (rna) virus with predominant fecal oral spread. traditionally in western europe it is associated with travel to endemic countries, but an increasing number of locally acquired cases have been reported throughout england. patients presenting with acute non-travel associated hev infection in south wales over a 25-month period were monitored, in an attempt to understand the clinical picture and epidemiology in our patient population. twenty-four patient ... | 2010 | 20872716 |
| is there evidence of recent hepatitis e virus infection in english and north welsh blood donors? | the risk of hepatitis e virus (hev) to blood safety remains unknown in england. reports of persistent hev infection with serious disease sequelae indicate that transfusion transmitted hev is not a trivial disease in immunosuppressed patients. materials and | 2010 | 21392024 |
| prevalence of hepatitis e virus infection in pigs at the time of slaughter, united kingdom, 2013. | since 2010, reports of infection with hepatitis e virus (hev) have increased in england and wales. despite mounting evidence regarding the zoonotic potential of porcine hev, there are limited data on its prevalence in pigs in the united kingdom. we investigated antibody prevalence, active infection, and virus variation in serum and cecal content samples from 629 pigs at slaughter. prevalence of antibodies to hev was 92.8% (584/629), and hev rna was detected in 15% of cecal contents (93/629), 3% ... | 2015 | 26196216 |
| indigenous hepatitis e in england and wales from 2003 to 2012: evidence of an emerging novel phylotype of viruses. | enhanced surveillance and molecular characterisation studies of hepatitis e virus (hev) in england and wales have been undertaken since 2003. the dynamics of hepatitis e have changed recently with an increase in the number of indigenous cases and an observed viral shift. | 2014 | 24273173 |
| autochthonous hepatitis e in scotland. | hepatitis e virus is well recognized cause of acute hepatitis. traditionally hepatitis e virus (hev) infections were generally associated with travel to asia and africa. autochthonous hepatitis e is recognized as a major cause acute hepatitis in england and wales. however, autochthonous hepatitis e has never been documented in scotland. | 2013 | 24200818 |
| hepatitis e virus in england and wales: indigenous infection is associated with the consumption of processed pork products. | indigenously acquired hepatitis e infections have increased substantially in england and wales since 2010. epidemiological investigations were undertaken to determine risk factors for the acquisition of infection. a case-control study (25 cases, 75 controls) was used to test the hypothesis that hepatitis e infection was related to consumption of pork products. in a multivariable model, consumption of pork pie [odds ratio (or) 6·33, 95% confidence interval (ci) 1·41-28·48, p = 0·009] and consumpt ... | 2014 | 24054519 |
| pork products associated with human infection caused by an emerging phylotype of hepatitis e virus in england and wales. | since 2010, human hepatitis e infections have increased in england and wales. most cases are locally acquired and caused by hepatitis e virus genotype 3 (hev g3). hev g3 is linked to the consumption of pork products. the increase is associated with the emergence of a new phylotype, hev g3-group 2 (g3-2, also known as g3abcdhij). sixty individuals with confirmed hepatitis e infection and no history of travel outside the uk were recruited: 19 were infected with hev g3-group 1 (g3-1 or g3efg) and 4 ... | 2017 | 28756783 |