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epidemiology of imported cutaneous leishmaniasis at the hospital for tropical diseases, london, united kingdom: use of polymerase chain reaction to identify the species.abstract. this study reviewed all patients diagnosed with imported cutaneous leishmaniasis (cl) at the hospital for tropical diseases in london, united kingdom, over an 11-year period. diagnostic and epidemiologic information was collected prospectively for all patients with imported cl to this hospital during 1998-2009. a total of 223 patients were given a diagnosis of cl. ninety patients were diagnosed with old world cl, which was caused most commonly by leishmania donovani complex (n = 20). a ...201222232460
antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (phaeophyceae) from british and irish waters.in the continuation of our research on seaweeds, crude extracts of 21 brown algae collected from the south coast of england and the west coast of ireland were screened for in vitro trypanocidal, leishmanicidal and antimycobacterial activities. mammalian stages of a small set of parasitic protozoa; i.e. trypanosoma brucei rhodesiense, t. cruzi and leishmania donovani, and the tubercle bacillus mycobacterium tuberculosis were used as test organisms. the extracts were also evaluated for selectivity ...201020564461
antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three british and irish red algae.as part of our continuing research on seaweeds, we have screened the crude extracts of 23 red marine algae collected from england and ireland. the clinically important blood-stage life forms of trypanosoma brucei rhodesiense, t. cruzi, leishmania donovani and mycobacterium tuberculosis were used as test organisms in the in vitro assays. the selectivity of the extracts was determined by using mammalian skeletal myoblast (l6) cells. all algal extracts showed activity against t. brucei rhodesiense, ...201020077438
antiprotozoal, antimycobacterial and cytotoxic potential of some british green algae.in the continuation of our search for natural sources for antiprotozoal and antitubercular molecules, we have screened the crude extracts of four green marine algae (cladophora rupestris, codium fragile ssp. tomentosoides, ulva intestinalis and ulva lactuca) collected from the dorset area of england. trypanosoma brucei rhodesiense, trypanosoma cruzi, leishmania donovani and mycobacterium tuberculosis were used as test organisms in the in vitro assays. the selective toxicity of the extracts was a ...201019960429
regulation of leishmania populations within the host. v. resistance to l.donovani in wild mice.samples of wild mus musculus from two populations in areas endemic for leishmaniasis and from seven populations in non-endemic areas were found to be uniformly resistant when tested for their early response to leishmania donovani infection. males from one endemic and one non-endemic population were crossed to females from two inbred strains of mice carrying the susceptible allele for the innate resistance gene, lsh, on different genetic backgrounds. bimodality of liver parasite counts and a clos ...19836854699
[kala-azar; clinical and physiopathological study a propos of a new case studied in switzerland].kala-azar, a parasitic disease caused by leishmania donovani, is usually found in tropical areas but may occasionally occur in other regions such as the mediterranean. a case of kala-azar in a women who had been on a holiday in greece is reported. the parasite was demonstrated in lymph node biopsies and bone marrow smears and treatment with stibogluconate was begun. high levels of circulating immune complexes were demonstrable before and during the demonstration of parasites; the immune complexe ...1979219473
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