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emergence of klebsiella pneumoniae carbapenemase-producing proteus mirabilis in hangzhou, china.carbapenems are used to treat severe infections caused by multi-drug-resistant organisms, however, the emergence of carbapenem-resistant bacterial isolates is becoming an increasing therapeutic challenge. since the first klebsiella (k.) pneumoniae carbapenemase (kpc)-producing k. pneumoniae was reported in 2001, kpc-producing isolates have been found increasingly, specially in enterobacteriaceae. the aim of this study was to characterize the mechanisms of a carbapenem-resistant proteus (p.) mira ...201021034629
emergence of proteus mirabilis harboring blakpc-2 and qnrd in a chinese hospital.nineteen carbapenem-nonsusceptible proteus mirabilis isolates were recovered from intensive care units in the second affiliated hospital of zhejiang university during a 3-month period. the isolates showed a high level of resistance against ciprofloxacin, in addition to their resistance against the carbapenems. pulsed-field gel electrophoresis (pfge) analysis showed that these isolates belonged to three clonal strains. pcrs and dna sequence analysis of the carbapenemase and other β-lactamase gene ...201222354308
antimicrobial susceptibilities of aerobic and facultative gram-negative bacilli from intra-abdominal infections in patients from seven regions in china in 2012 and 2013.to evaluate the antimicrobial susceptibility of gram-negative bacilli that caused hospital-acquired and community-acquired intra-abdominal infections (iais) in china between 2012 and 2013, we determined the susceptibilities to 12 antimicrobials and the extended-spectrum β-lactamase (esbl) statuses of 3,540 iai isolates from seven geographic areas in china in a central laboratory using clsi broth microdilution and interpretive standards. most infections were caused by escherichia coli (46.3%) and ...201526482308
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