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[the ratios and kinds of clinical bacteria isolated in taiwan's large-size hospitals].the prevalence of clinical bacteria, as isolated from linko chang-gung memorial hospital (2,300 beds) in the period january 1985 to december 1986 and from taipei veterans general hospital (2,300 beds) during the period january 1986 to december 1986, was analyzed with the following findings: (i) the isolation ratio of anaerobic and aerobic or facultative bactria during the period of investigation were 7.8% (5,513/70,799) and 92.2% (65,286/70,799), respectively. (ii) of the total aerobic or facult ...19892791722
the prognostic factors of adult gram-negative bacillary meningitis.seventy-seven patients with gram-negative bacillary meningitis (gnbm), 57 males and 20 females, aged 17-86 years, were identified at kaohsiung chang gung memorial hospital, over an 11-year period. fifty-four infections were community-acquired, and 23 were nosocomial; 49 were spontaneous and 28 occurred after head surgery or neurosurgery. the organisms most frequently involved were klebsiella pneumoniae, pseudomonas aeruginosa, escherichia coli, and acinetobacter. rarer pathogens included citroba ...19989777518
antimicrobial susceptibilities among clinical isolates of extended-spectrum cephalosporin-resistant gram-negative bacteria in a taiwanese university hospital.infections caused by gram-negative bacteria with resistance to extended-spectrum cephalosporins require the identification of effective alternative antimicrobial therapy. to determine the role of other pre-existing or currently available antimicrobial agents in treating infections caused by these multidrug-resistant pathogens, we evaluated the in vitro susceptibilities of these agents in 411 non-duplicate isolates of extended-spectrum cephalosporin-resistant gram-negative bacteria recovered betw ...200211751769
multicenter surveillance of antimicrobial resistance of major bacterial pathogens in intensive care units in 2000 in taiwan.a susceptibility surveillance study of 1,274 bacterial isolates recovered from various clinical specimens from patients in intensive care units (icus) of five major teaching hospitals was carried out from march, 2000, to june, 2000, in taiwan. this study demonstrated a high rate (66%) of oxacillin resistance in staphylococcus aureus (orsa), a high rate of nonsusceptibility to penicillin (intermediate, 50% and highly resistant, 8%), and high rates of cefotaxime nonsusceptibility for s. pneumoniae ...200111822777
metallo-beta-lactamase-producing enterobacteriaceae isolates in a university hospital in taiwan: prevalence of imp-8 in enterobacter cloacae and first identification of vim-2 in citrobacter freundii.a total of 9082 clinical isolates of enterobacteriaceae other than klebsiella spp. collected in 1999 and 2000 at a university hospital in taiwan were investigated for the production of metallo- beta-lactamases (mbls). thirty-six (2.9%) of the 1261 enterobacter cloacae isolates and one (0.3%) of the 340 citrobacter freundii isolates were found to carry bla(imp-8) and bla(vim-2), respectively, by colony hybridization, pcr and sequence analysis. the imp-8 producers were recovered from 20 patients a ...200212356794
cefotaxime-resistant citrobacter freundii in isolates from blood in a tertiary teaching hospital in northern taiwan.from january 2002 to december 2003, 12 patients in a tertiary teaching hospital in northern taiwan had bloodstream infections caused by citrobacter freundii. seven of the 12 isolates were resistant to cefotaxime. using polymerase chain reaction and dna sequencing, 3 of the 7 cefotaxime-resistant c. freundii isolates were found to carry extended-spectrum beta-lactamase (esbl). ampc beta-lactamase genes were also detected in all strains of c. freundii. all strains of c. freundii with mics >or=4 mg ...200717572502
in vitro activity of isepamicin and other aminoglycosides against clinical isolates of gram-negative bacteria causing nosocomial bloodstream infections.isepamicin is a newly introduced aminoglycoside in taiwan. since in vitro data for isepamicin against nosocomial gram-negative bloodstream infection from taiwan are limited, we compared the activity of isepamicin, amikacin, gentamicin and tobramycin against nosocomial gram-negative blood isolates.200718087627
bacteraemia caused by non-freundii, non-koseri citrobacter species in taiwan.this study analysed the clinical characteristics of bacteraemia due to unusual citrobacter species. all non-freundii and non-koseri citrobacter isolates were identified to species level by two commercial identification methods and 16s rrna gene sequence analysis. a total of 306 patients with citrobacter spp. bacteraemia were identified from january 2000 through december 2009. four patients (1.3%) had c. braakii bacteraemia, and one had c. amalonaticus and c. sedlakii sepsis, respectively. miside ...201020708303
arsenite-oxidizing and arsenate-reducing bacteria associated with arsenic-rich groundwater in taiwan.drinking highly arsenic-contaminated groundwater is a likely cause of blackfoot disease in taiwan, but microorganisms that potentially control arsenic mobility in the subsurface remain unstudied. the objective of this study was to investigate the relevant arsenite-oxidizing and arsenate-reducing microbial community that exists in highly arsenic-contaminated groundwater in taiwan. we cultured and identified arsenic-transforming bacteria, analyzed arsenic resistance and transformation, and determi ...201021216490
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