| presence and impact of the exercise-induced collapse associated dnm1 mutation in labrador retrievers and other breeds. | the impact of the mutation causing dynamin 1 (dnm1)-associated exercise-induced collapse (d-eic) was determined in a retrospective genetic survey. the frequency of dnm1 mutant allele carriers in labrador retrievers from conformation show, field trial/hunt test, pet or service lines ranged from 17.9% to 38.0% and the frequency of homozygous mutant (ee genotype) individuals ranged from 1.8% to 13.6%; 83.6% of these ee labradors were reported to have collapsed by 4years of age. dnm1 mutation carrie ... | 2011 | 21782486 |