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cross-reactivity to highly pathogenic avian influenza h5n1 viruses after vaccination with nonadjuvanted and mf59-adjuvanted influenza a/duck/singapore/97 (h5n3) vaccine: a potential priming strategy.antigenically well-matched vaccines against highly pathogenic avian influenza h5n1 viruses are urgently required. human serum samples after immunization with mf59 or nonadjuvanted a/duck/singapore/97 (h5n3) vaccine were tested for antibody to 1997-2004 human h5n1 viruses. antibody responses to 3 doses of nonadjuvanted vaccine were poor and were higher after mf59-adjuvanted vaccine, with seroconversion rates to a/hongkong/156/97, a/hongkong/213/03, a/thailand/16/04, and a/vietnam/1203/04 of 100% ...200515776364
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