| the effect of emodin, an anthraquinone derivative extracted from the roots of rheum tanguticum, against herpes simplex virus in vitro and in vivo. | herpes simplex viruses (hsv-1 and -2) are important pathogens for humans and the discovery of novel anti-hsv drugs with low toxicity deserves great efforts. rhubarb is one of the oldest and best-known traditional chinese medicines. we initiated this study to test if emodin is the active ingredients from rheum tanguticum (r. tanguticum, one of the chinese rhubarb) against hsv infection and to investigate its antiviral activity on hsv infection in tissue culture cells and in a mouse model. | 2010 | 21050882 |