| emergence of fluoroquinolone-resistant neisseria meningitidis--minnesota and north dakota, 2007-2008. | meningoccocal disease causes substantial morbidity and mortality; approximately 10% of cases are fatal. among those who survive, 10%-15% have long-term sequelae. nasopharyngeal carriage of neisseria meningitidis is a precursor to disease; however, the majority of carriers do not develop disease. household and other close contacts of persons with meningococcal disease have a higher risk for carriage and therefore invasive disease. these persons should receive antibiotic chemoprophylaxis to elimin ... | 2008 | 18288075 |
| emergence of ciprofloxacin-resistant neisseria meningitidis in north america. | we report on three cases of meningococcal disease caused by ciprofloxacin-resistant neisseria meningitidis, one in north dakota and two in minnesota. the cases were caused by the same serogroup b strain. to assess local carriage of resistant n. meningitidis, we conducted a pharyngeal-carriage survey and isolated the resistant strain from one asymptomatic carrier. sequencing of the gene encoding subunit a of dna gyrase (gyra) revealed a mutation associated with fluoroquinolone resistance and sugg ... | 2009 | 19246360 |
| in brief: meningococcal prophylaxis. | | 2008 | 18391897 |