| serotype-specific outbreak of group b meningococcal disease in iquique, chile. | from 1979 to august 1987, there have been 178 cases of meningococcal disease in iquique, chile, a city of about 140,000. the attack rate for the last 5 years has been in excess of 20/100,000 per year, more than 20 times greater than for the country overall. the mortality rate was 6%. the disease occurred in patients with ages from 4 months to 60 years, but 89% of cases were in patients less than 21 years. the largest number of cases were in the age group 5-9 years (n = 54), but the highest incid ... | 1990 | 2116973 |
| efficacy, safety, and immunogenicity of a meningococcal group b (15:p1.3) outer membrane protein vaccine in iquique, chile. chilean national committee for meningococcal disease. | a meningococcal group b (15:p1.3) outer membrane protein vaccine was tested for efficacy in a randomized, double-blind controlled study in iquique, chile. a total of 40 811 volunteers, ages 1-21 years, enrolled in the study. volunteers received two doses of vaccine six weeks apart by jet injector. both the experimental vaccine and the control vaccine (menomune, a, c, y and w135 meningococcal polysaccharide vaccine) were well tolerated with minor side-effects. active surveillance for suspected ca ... | 1995 | 7483804 |