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[first isolation in france of a penicillinase-non producing neisseria gonorrhoeae with high level tetracycline resistance].we report the first isolation in france of a penicillinase-non producing neisseria gonorrhoeae with high level tetracycline resistance. the minimal inhibitory concentrations (mics) of nine antibiotics were determined by agar dilution for the tetracycline resistant strain and 39 other penicillinase-non producing n. gonorrhoeae strains which were isolated during the same year (1989), in toulouse. no difference was observed between the mics except for the tetracycline (tetracycline-resistant strain ...19911909019
lower genital tract infections in women: comparison of clinical and epidemiologic findings with microbiology.we screened 392 women attending the laboratory of microbiology of toulouse purpan hospital for symptoms of lower genital tract infection for six microorganisms. rates of isolation of neisseria gonorrhoeae, chlamydia trachomatis, candida albicans, mycoplasma hominis, and gardnerella vaginalis were 1%, 7.7%, 29.8%, 23.8%, and 37.5%, respectively. trichomonas vaginalis was detected by direct examination in specimens from 3.1% of patients. another goal of this study was to determine the relative pre ...19883135608
[use of josamycin in the eradication of meningococcus].because of their in vitro and in vivo activity on neisseria meningitidis, good salivary and tonsillar tissue levels, high safety and non-penetration through the meningeal barrier, macrolides are agents of choice for treating meningococcus carriers. to assess the value of josamycin for eliminating meningococci in carriers, we carried out a 14-month study with bacteriological control. 27 carriers identified (throat specimens) among contacts of 28 children with meningococcal meningitis hospitalized ...19846739146
[isolation and characterization of a beta-lactamase-specifying plasmid in a strain of "neisseria gonorrhoeae" (author's transl)].gcl3, a beta-lactamase-producing, penicillin resistant strain of neisseria gonorrhoeae isolated in toulouse (france), and gcl51, a penicillin susceptible strain, were examined for their plasmid content. agarose-gel electrophoresis following or not ultracentrifugation in a cesium chloride-ethidium bromide gradients, revealed, for both strains a 3.9-kilobase (kb) (2.6 megadaltons) cryptic plasmid. penicillin resistant strain gcl3 also contained a 37 kb (24.5 megadaltons) and a 7.3 kb (4.8 megadalt ...19816271037
study of the in vitro activity of new cephalosporins on strains of neisseria gonorrhoeae of the toulouse region.the study was carried out with 50 strains of gonococci. susceptibility to the antibiotics was determined by standard sensitivity test, by systematic test for beta-lactamase and by measurement of the mics. the cephalosporins tested were: moxalactam, cefotaxime, ceftriaxone, cefotiam, cefoxitin, cefazolin and cephalothin. their activities were also compared with other beta-lactams, namely penicillin and ampicillin. the efficacy in vitro of the cephalosporins: in the lead, ceftriaxone, remarkably a ...19816265158
[surveillance of neisseria gonorrhoeae strains isolated in toulouse. in vitro antibiotic sensitivity and plasmid content].the minimal inhibitory concentration (mic) of twelve antibiotics was determined by the method of dilution in agar for 50 non penicillinase-producing and 15 penicillinase-producing neisseria gonorrhoeae (ppng) strains. the commonly used antibiotics are active in vitro against all the strains. for the non ppng stains, no difference was observed between the mics with a previous investigation, in 1980. new quinolones are highly active against all the strains tested but two, with decreased sensitivit ...19883141883
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