| outcome of pre-hospital antibiotic treatment of meningococcal disease. | to assess the effect of pre-hospital antibiotic treatment given by general practitioners to patients with meningococcal disease. | 1998 | 9731919 |
| period prevalence and case-fatality rate associated with distinctive clone complexes of neisseria meningitidis serogroups b and c. | in a recent 20-year danish survey, neisseria meningitidis phenotypes b:15:p1.7,16 and c:2a:p1.2,5 were associated with an increased case-fatality rate of meningococcal disease - 15% and 23% - compared to the case-fatality rate of 8% for any other strain. the aim of the present study was to investigate (i) the mutual genetic relatedness of strains with phenotype b:15:p1.7,16, phenotype c:2a:p1.2,5 or serologically related phenotypes; (ii) the changes in the prevalence of distinctive clone complex ... | 2002 | 12172741 |
| pre-hospital parenteral antibiotic treatment of meningococcal disease and case fatality: a danish population-based cohort study. | studies about the efficiency of pre-hospital antibiotic treatment of meningococcal disease are conflicting. we examined the case fatality rate in patients with meningococcal disease treated with pre-hospital antibiotics. | 2002 | 12387769 |
| neisseria meningitidis phenotypic markers and septicaemia, disease progress and case-fatality rate of meningococcal disease: a 20-year population-based historical follow-up study in a danish county. | the incidence rate (ir) and case-fatality rate (cfr) of meningococcal disease increased during the late 1980s and early 1990s in north jutland county, denmark. we examined the hypothesis that phenotypic markers of neisseria meningitidis are predictors of septicaemia with or without meningitis, rapid disease progress and fatal outcome of meningococcal disease and we studied whether changes in ir and cfr over time might be related to emergence or spread of certain phenotypes. this follow-up study ... | 2003 | 12543925 |
| seasonal variation in meningococcal disease in denmark: relation to age and meningococcal phenotype. | seasonal variation has been shown in meningococcal disease (md), but it is not known whether seasonal variation depends on age, gender and meningococcal phenotype. based on complete registration of md in north jutland county, denmark, during 1980-1999 (n = 413 cases), a poisson regression model of a sinusoidal form was used to examine: (i) whether the seasonal variation in md follows a sinusoidal pattern; (ii) the magnitude of seasonal variation in md; and (iii) whether seasonal variation is rel ... | 2003 | 12839148 |
| positive blood cultures and diagnosis of bacterial meningitis in cases with negative culture of cerebrospinal fluid. | the diagnosis of bacterial meningitis may be established through positive blood cultures in cases with negative culture of cerebrospinal fluid (csf). however, information is sparse regarding how often the aetiological diagnosis is determined by blood culture alone. therefore, we undertook a retrospective study of patients with meningitis and a blood culture-based bacterial diagnosis in north jutland county, denmark in 1997-2005. patients were included if they had 1) a microscopy- and culture-neg ... | 2008 | 17907046 |