Publications

serological studies of mucosal disease virus in england and wales.	a survey of the cattle population in england and wales showed that about 62 per cent of animals had neutralising (sn) antibody to bvd-md virus in their serum. fewer seropositive individuals were detected by immunodiffusion (53 per cent), and complement fixation (cf) tests (34 per cent). the prevalence of antibody was not affected by herd size, but some variation was found between various regions of the country, and the proportion of animals seropositive rose markedly with age. the immunodiffusio ...	1978	203990
the distribution of antibodies to border disease virus among sheep in england and wales.	within a sample of the sheep population of england and wales, 10.8 per cent of 3506 individuals had immunodiffusion test antibody to bovine viral diarrhoea mucosal disease virus antigen. there were marked differences between various geographical regions in the proportion of sheep with antibody, and border disease may be more common in some areas than disease records indicate.	1978	214835
mucosal disease of cattle: a late sequel to fetal infection.	the introduction of a heifer which was persistently infected with bovine virus diarrhoea-mucosal disease virus into groups of pregnant cattle resulted in abortion, neonatal death, persistent infection and, subsequently, mucosal disease in the surviving progeny. cattle affected with mucosal disease were invariably seronegative at the time of investigation and subsequent cases occurred only in calves previously identified as seronegative and persistently infected. the detection of virus antigen by ...	1984	6328725
experimental production of fatal mucosal disease in cattle.	three outbreaks of mucosal disease were investigated. careful examination of 47 cattle that were persistently viraemic with bovine virus diarrhoea virus (bvdv) revealed no clinical disease, no or low levels of bvdv antibody and only non-cytopathic virus in their blood. the four animals with mucosal disease all showed clinical disease and both cytopathic and non-cytopathic virus in their blood. following post mortem examination, there were particularly high levels of cytopathic virus in gut tissu ...	1984	6087539
border disease in a flock of sheep: epidemiologic, laboratory, and clinical findings.	a flock of sheep in which border disease (bd) was enzootic was studied through a breeding season. at the beginning of the study (august 1981), 125 (82%) of 152 ewes were seropositive to the cross-reacting bovine viral diarrhea virus. within 7 months, 3 (18%) of 17 seropositive ewes retested had reverted to seronegative. of the remaining 21 ewes identified as seronegative, 7 (33%) converted to seropositive by the end of the study. triplet lambs were born, 2 of which exhibited clinical signs of bd ...	1986	3733503
fatal bvdv infection in adult cattle.		1993	8465509
severe disease in adult dairy cattle in three uk dairy herds associated with bvd virus infection.	during 1993 outbreaks of diarrhoea in adult dairy cows in three geographically unrelated herds were found to be caused by bovine viral diarrhoea virus (bvdv). the affected animals showed signs of acute watery diarrhoea, agalactia and pyrexia (39.4 to 42 degrees c). ulceration of the buccal mucosa, a mucoid nasal discharge and stiffness were inconsistent signs. the disease spread rapidly in each case. the diagnosis was confirmed by the isolation of non-cytopathic bvdv from blood and tissues and b ...	1994	8059512
long-term viral serology of semi-free-living and captive ungulates.	between 1973 and 1994, blood samples were collected at whipsnade wild animal park (uk) from three ungulate species kept in enclosures, including 28 european bison (bison bonasus), 37 scimitar-horned oryx (oryx dammah), and 49 père david's deer (elaphurus davidianus), and also from 144 semi-free-living chinese water deer (hydropotes inermis). these samples were tested for the presence of antibodies against three bovine viral diarrhea virus (bvdv)-like strains, three alpha-herpesvirus strains, enz ...	1998	9732031
prevalence of antibodies to bovine virus diarrhoea virus and other viruses in bulk tank milk in england and wales.	bulk tank milk samples from 1070 dairy herds in england and wales were tested by elisa for antibodies to bovine virus diarrhoea virus (bvdv). a subset of 341 herds was tested by elisa for antibodies to bovine herpesvirus 1 (bhv-1), bovine respiratory syncytial virus (brsv) and bovine coronavirus (bcv). none of the herds had less than 40 dairy cows and none had been vaccinated against bvdv. the prevalence of bvdv antibody-positive herds in the national population was estimated at 95 per cent and ...	1998	9586130
genetic typing of bovine pestiviruses from england and wales.	using rna purified directly from stored clinical specimens, a collection of 62 pestiviruses were typed by rt-pcr and sequencing within the 5'-untranslated region of the genome. all the specimens had been obtained in 1966/1967 from diary cattle in england and wales. eight further pestiviruses, grown in cell culture, were characterised in the same way. seven of these viruses were representatives of a panel of british isolates, obtained from cattle ten years before. the eighth was the virus used in ...	1999	10535769
seroprevalence of bvdv in cattle of different ages on 17 dairy farms in western england.		2007	17526896
bvdv in british alpacas.		2008	18552333
Establishing a pilot bovine viral diarrhoea virus eradication scheme in Somerset.	Beginning in April 2006, 41 farms were recruited onto a pilot Bovine viral diarrhoea virus (BVDV) eradication programme across the south of England with the majority of study herds concentrated in Somerset. Each herd was assessed and where relevant cleared of persistently infected (PI) animals. Seven farms dropped out before whole herd screening could be performed. Of the remaining 34 farms, 20 (59 per cent) were classified as infected although two of these were initially misclassified as BVDV-f ...	2011	22027186