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hepatitis c virus infection among first nation and non-first nation people in manitoba, canada: a public health laboratory study.demographic information and laboratory test results on 136 169 clinical serum specimens submitted to the public health laboratory in manitoba, canada, for hepatitis c virus (hcv) testing between january 1995 and december 2003 were analyzed. the difference in the clearance rates of hcv infection, without therapeutic intervention, and the hcv genotypes infecting first nation and non-first nation people were studied. the rates of co-infection of hcv-positive individuals with other hepatitis viruses ...200617110969
occult hepatitis b virus infection in a north american adult hemodialysis patient population.hepatitis b virus (hbv) infections continue to occur in adult hemodialysis units. a possible contributing factor is the presence of occult hbv (serum hepatitis b surface antigen [hbsag] negative but hbv dna positive). two hundred forty-one adult hemodialysis patients were screened for occult hbv. hbv dna testing was performed by real-time polymerase chain reaction (pcr) with 2 independent primer sets (core promoter and surface). two (0.8%) of the 241 patients were hbsag positive. of the remainin ...200415486926
hepatitis b immunization in a low-incidence province of canada: comparing alternative strategies.this study provides a comparative cost-effectiveness analysis of three universal immunization programs for hepatitis b virus (hbv). using three theoretical cohorts of infants, 10-year-olds, and 12-year-olds, a universal immunization program was compared with a prenatal screening/newborn immunization program involving testing of prepartum women and immunization of newborns of hbsag-positive mothers. a markov long-term outcome model used manitoba data to estimate costs and health outcomes across t ...19979343806
the risks of transmission of acute hepatitis a and b virus infection in an urban centre.in a large urban centre of a developed nation, 63 household contacts of 20 index cases with acute hepatitis a virus infection and 95 household contacts of 29 index cases with acute hepatitis b virus infection were prospectively followed for 2 years to document the risk of acquiring acute hepatitis from the index case. twenty-one of 63 (33%) hepatitis a virus household contacts had serologic evidence of previous hepatitis a virus infection on the initial serum sample. of the remaining 42 suscepti ...19947963411
epidemiological study of hepatitis b virus infection in manitoba, canada, 1992-2003.in comparison with other canadian provinces and most western countries, the province of manitoba maintains a different vaccination policy for hepatitis b. this policy provides selective antenatal screening for hepatitis b in women and an inoculation program for hepatitis b vaccination for fourth-grade pupils. there has been increasing concern for this policy with regard to its influence on secular trends of acute hepatitis b incidence in manitoba. this created a need to summarise the epidemiolog ...200515959814
antibody to hepatitis d virus (delta agent) in selected manitoba residents, 1974-1986.the prevalence of antibody to hepatitis d virus (hdv) was determined in serum samples collected from 174 manitoba residents between 1974 and 1986. anti-delta was detected in five of 123 hbv-infected individuals for an overall prevalence of 4.1%. three of 54 (5.5%) persons who were sampled in the period 1974-77 were anti-delta positive, as were two of 69 (2.9%) sampled between 1982 and 1986 (p greater than 0.05). four of 31 (12.9%) acute hepatitis b patients, and one of 92 (1.1%) chronic hbsag ca ...19883135966
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