| seroepidemiology of hepatitis a and hepatitis b virus infection in a gurkha community in singapore. | the overall prevalence of hepatitis a virus (hav) infection among the gurkhas and their families stationed in singapore was 83.2%, with antibody to hav detected in 67 (38.1%) of 176 children under 5 years of age, 121 (76.6%) of 158 children between 5 and 14 years, and 600 (97.9%) of 613 older children and adults over age 15 years. children born in singapore (102/223 or 45.7%) had a significantly lower crude prevalence than those born in nepal (85/110 or 77.3%) (p < 0.000001). the age-adjusted di ... | 1993 | 8283176 |
| immunogenicity and safety of an inactivated hepatitis a vaccine amongst singaporeans. | the immunogenicity and reactogenicity of an inactivated hepatitis a virus (hav) vaccine was studied in healthy singaporean adult volunteers. one hundred and forty healthy volunteers with normal alanine (alt) and aspartate (ast) transaminases and no previous exposure to hav, received three 1 ml doses (720 elisa units) of an inactivated hav vaccine (smithkline beechams biologicals) following a 0, 1, 6 months vaccination schedule. all subjects were asked to record and grade the severity of any reac ... | 1995 | 8629058 |
| acute hepatitis a in singapore: importance of shellfish ingestion in a non-epidemic period. | a case-control study based on 28 serologically confirmed cases of hepatitis a and 42 home contacts with no recent or past evidence of hepatitis a virus (hav) infection was conducted to determine the importance of shellfish exposure in the transmission of hav during a non-epidemic period in singapore. it was found that consumption of partially-cooked cockles (anadara granosa) was significantly associated with the illness (p less than 0.001). no other types of locally available shellfish including ... | 1987 | 2833148 |
| changing epidemiological patterns of hepatitis a infection in singapore. | introduction: singapore has experienced remarkable socioeconomic progress over the last few decades, with a corresponding rise in standards of sanitation and living conditions. we undertook a study to describe its epidemiological trends of hepatitis a over the last 2 decades. materials and methods: we analysed the epidemiological data on all laboratoryconfi rmed cases of hepatitis a from 1990 to 2009. we also described 3 outbreaks which occurred in 1991, 1992 and 2002. to determine the changing ... | 2011 | 22206052 |
| prevalence of hepatitis a virus infection among sewage workers in singapore. | to determine whether or not occupational exposure to sewage is associated with a higher seroprevalence of hepatitis a virus (hav) infection, 600 sewage workers in singapore were tested for total (igg and igm) antibody to hav by enzyme immunoassay. using logistic regression with stepwise procedure, the adjusted seroprevalence of sewage workers was 2.2 times higher than that of another non-occupationally exposed population group. seroprevalence was significantly correlated with age and educational ... | 1994 | 8062868 |
| seroprevalence of antibodies against hepatitis a (anti-hav) in singapore: the nfdd experience. | at the 4th national foundation for digestive disease (nfdd) day in 1991 where public lectures on prevention of hepatitis and early detection of hepatocellular carcinoma were given, screening of sera obtained from 364 registrants for antibodies to hepatitis a (igg) was undertaken. the overall sero-prevalence rate was 50%, with 55% for males and 46% for females with antibodies for hav. none of the subjects below 20 years old had antibodies to hav. this rose to 16% for those 21-30 years old and 92% ... | 1995 | 7570129 |
| hepatitis a updated. | | 1995 | 7570128 |