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respiratory syncytial virus infections within families.to examine intrafamily spread of respiratory syncytial virus infections and their associated illnesses, 36 families with 188 members were studied during an outbreak of such infections. nurses visited every three to four days to obtain specimens for viral isolation and interview household members. the virus infected 44.4 per cent of families, and 21.9 per cent of all members. all age groups had appreciable attack rates (with a range of 16.8 per cent in adults to 29.4 per cent in infants). in infe ...1976173995
neonatal respiratory syncytial virus infection.respiratory syncytial virus infections are thought to be uncommon in the first month of life. during a community outbreak, we prospectively studied such infection in our neonatal units. of 82 neonates studied, 66 were hospitalized for six days or longer, and 23 (35 per cent) acquired this virus. four infants died, two unexpectedly. infected infants had a significantly shorter gestation and birth weight. illness was often atypical, with nonspecific signs, especially in infants under three weeks o ...1979759915
respiratory syncytial virus in nurseries. 1979759920
occurrence of groups a and b of respiratory syncytial virus over 15 years: associated epidemiologic and clinical characteristics in hospitalized and ambulatory children.over 15 years respiratory syncytial virus (rsv) isolates from 1209 hospitalized and ambulatory children were examined for strain group and in a subset for subgroup to determine the associated epidemiologic and clinical characteristics. three patterns of yearly outbreaks existed: (1) strong predominance of group a strains (9 years with 83%-100% a strains), (2) relatively equal proportions of group a and b strains (4 years), and (3) strong predominance of group b strains (78%-85%) in 2 years, sepa ...19902230258
severe respiratory disease in dairy cattle in new york state associated with bovine respiratory syncytial virus infection.severe respiratory disease associated with bovine respiratory syncytial virus (brsv) infection has been identified in dairy cattle in new york state. the cases identified occurred in dairy calves and heifers. the disease was characterized in 4 animals by pathologic changes including interstitial pneumonia, necrotizing bronchiolitis with multinucleated syncytial epithelial cells and interstitial emphysema. brsv antigen was demonstrated in lung samples or was isolated in tissue culture in all 4 ca ...19854053607
respiratory syncytial virus-related apnea in infants. demographics and outcome.medical records of 261 hospitalized patients less than 1 year old with documented respiratory syncytial virus (rsv) infection were reviewed to determine the incidence of rsv-associated apnea and the accompanying risk of subsequent apnea or death. apnea in association with rsv infection occurred in 18% of the infants. premature birth and a young postnatal age were risk factors for development of apnea with rsv disease. apnea of prematurity appeared to be a significant risk factor for rsv apnea de ...19846702769
acute respiratory tract infection in daycare centers for older persons.to evaluate the rate of specific pathogens and clinical syndromes associated with acute respiratory tract infections (arti) in frail older persons attending daycare.19957806736
antigenic and nucleic acid analysis of nosocomial isolates of respiratory syncytial virus.monoclonal antibodies and ribonuclease protection were used to analyze antigenic and genomic diversity among 42 isolates of group a respiratory syncytial virus (rsv) from studies of nosocomial rsv carried out at the university of rochester during the 1974-1975 and 1975-1976 rsv seasons. three distinct subgroups or lineages and a total of 12 viral variants were present. against this background of diversity, an outbreak was recognized that included 13 indistinguishable isolates occurring during a ...19938440927
rehospitalization with respiratory syncytial virus after neonatal intensive care unit discharge: a 3-year follow-up.this study sought to determine 1) the incidence of rehospitalization with respiratory syncytial virus (rsv) infection within a 3-year follow-up among infants discharged from the neonatal intensive care unit (nicu), and 2) to examine associations between age at readmission and medical and sociodemographic characteristics among infants rehospitalized with rsv.19979382909
circulation patterns of genetically distinct group a and b strains of human respiratory syncytial virus in a community.human respiratory syncytial virus (hrsv) is classified into two major groups, a and b, each of which contains multiple variants. to characterize the molecular epidemiology of hrsv strains over time, sequencing studies of a variable region of the attachment protein gene from a single community in the united states during 5 successive years were performed. phylogenetic analysis revealed distinct clades (genotypes) that were further classified in subtypes based on > or = 96% nucleotide similarity. ...19989747732
population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children.respiratory syncytial virus (rsv), influenza virus, and parainfluenza viruses (piv) cause significant morbidity in young children. although only influenza virus infection and illness is currently vaccine-preventable, vaccines are under development for rsv and piv. we established a prospective, active population-based surveillance network to provide precise estimates of hospitalization rates for viral acute respiratory illness (ari) in young children and to measure the potential impact of enhance ...200415173503
pulmonary complications of interpandemic influenza a in hospitalized adults.to define the pulmonary complications of influenza during the current interpandemic period, we reviewed clinical, laboratory, and radiographic data from 193 adults (> or =18 years old) (1999-2003) who were hospitalized with influenza a during 4 winters.200717330794
is clinical recognition of respiratory syncytial virus infection in hospitalized elderly and high-risk adults possible?the clinical and radiographic features of respiratory syncytial virus (rsv) infection in elderly hospitalized persons have not been described in detail, to our knowledge, despite its relative frequent occurrence.200717330796
comparison of clinical features of pediatric respiratory syncytial virus and human metapneumovirus infections. 200919888849
respiratory syncytial virus infections in previously healthy working adults.during 1975-1995, a total of 2960 healthy adults, 18-60 years of age, were prospectively evaluated for respiratory virus infections. of these subjects, 211 (7%) acquired respiratory syncytial virus (rsv) infection. the infections were symptomatic in 84% of subjects, involved only the upper respiratory tract in 74%, and included lower respiratory tract symptoms in 26%. overall, 40% of the subjects were febrile. lower respiratory tract signs developed in 26%. rsv illnesses were more prolonged than ...200111512084
concurrent respiratory syncytial virus and influenza a infections in the institutionalized elderly and chronically ill.during a community outbreak of respiratory syncytial virus and influenza a/texas/77 infections, we investigated 71 cases of upper respiratory illness at a chronic disease hospital using a surveillance system plus viral and serologic studies. of the 32 patients with an etiologic diagnosis, seven had respiratory syncytial virus, 24 had influenza, and one had dual infections with respiratory syncytial virus and influenza. no definite etiologic diagnosis was made in the remaining 39 patients. a comp ...19807396314
nosocomial viral infections: i. epidemiology and significance.viral illnesses in strong memorial hospital were monitored over a 17-month period. using criteria based primarily on the incubation periods for a number of common virus infections, the infections we found were classified as hospital- or community-acquired. hospital-acquired viral infections occurred on most hospital services; the majority of infections occurred on the pediatric and psychiatric services. infections due to herpesviruses were seen more frequently in a group of patients aged 14 year ...19806274823
nosocomial viral infections: ii. guidelines for prevention and control of respiratory viruses, herpesviruses, and hepatitis viruses.this article reviews the most likely mechanisms of transmission of the commonly encountered respiratory viruses (influenza, respiratory syncytial virus, parainfluenza, rhinovirus), herpesviruses, and hepatitis viruses, and presents the guidelines used currently for prevention and control that are in use at strong memorial hospital.19806256306
lower respiratory tract illness in the first two years of life: epidemiologic patterns and costs in a suburban pediatric practice.the epidemiologic patterns and the economic impact of acute lower respiratory tract illness (lrti) in children under age two were studied using data collected from november 1, 1971-august 30, 1975 in a suburban pediatric practice in monroe county, new york. lrti was responsible for 23 illness episodes per 100 child-years among children in their first two years of life. this indicates that a cohort of 100 children might be anticipated to have 46 lrti episodes from birth until their second birthda ...19883337302
serologic evidence of respiratory syncytial virus infection in nursing home patients. 19902197348
variation in severity of respiratory syncytial virus infections with subtype.two major subtypes of respiratory syncytial virus have been identified. this study assessed the hypothesis that a-subtype infections were more severe than b-subtype infections among the 157 infants hospitalized in two hospitals in rochester, n.y., during two winters. severity was measured both by specific clinical observations and by a severity index that was derived empirically. among all subjects, several clinical observations suggested that a-subtype infections were more severe. for example, ...19902115082
nosocomial respiratory syncytial virus infections.we studied the frequency and severity of respiratory syncytial virus infections acquired nosocomially on an infants' ward during a community outbreak. every three or four days all infants and staff were examined, and specimens were obtained for viral isolation. during two months, 14 of 44 contact infants acquired the virus. all were ill, and four had pneumonia. infected infants had a significantly longer mean hospital stay (21.5 days) than uninfected ones (9.2 days, p less than 0.001). risk of n ...19751186836
estimating the hospitalization burden associated with influenza and respiratory syncytial virus in new york city, 2003-2011.hospitalization burden associated with influenza and respiratory syncytial virus (rsv) is uncertain due to ambiguity in the inference methodologies employed for its estimation.201525980600
temporal trends and factors associated with pediatric hospitalizations with respiratory infection.asthma is the leading cause of emergency room visits in children, and those with asthma tend to suffer from more severe consequences of respiratory tract infections. the aims of this study were among children who required hospitalization, compare differences between those admitted with or without respiratory infection, describe changes in yearly proportion of asthma among the children admitted with a respiratory infection in new york city from 2006 to 2012 and ascertain how asthma affected the a ...201626364908
circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults.the specificity and duration of circulating human antibody-secreting cells (ascs) after vaccination have been well described, but characteristics of ascs during acute respiratory infections have not been well studied.201020979459
human parainfluenza virus type 3 (hpiv 3) viral community-acquired pneumonia (cap) mimicking swine influenza (h1n1) during the swine flu pandemic.the swine influenza (h1n1) pandemic began in mexico in 2009 and quickly spread worldwide. during the h1n1 pandemic, many patients were admitted to the winthrop-university hospital with influenza-like illnesses (ilis). many hospitalized adults had h1n1 pneumonia diagnosed by laboratory or clinical criteria. however, the laboratory diagnosis of h1n1 was problematic. the rapid influenza (quickvue a/b [quidel, san diego, ca]) test frequently showed false-negative results. reverse transcriptase-polym ...201120888645
outbreak of parainfluenza virus type 3 in a neonatal intensive care unit.parainfluenza virus (piv) causes > 30% of all acute respiratory infections in infants and children and is second only to respiratory syncytial virus as a cause of lower respiratory tract infection. however in the neonatal intensive care unit (nicu), piv outbreaks are highly uncommon. this case report describes an outbreak of 3 cases of piv type 3 in a regional nicu.200919085679
monitoring the impact of influenza by age: emergency department fever and respiratory complaint surveillance in new york city.the importance of understanding age when estimating the impact of influenza on hospitalizations and deaths has been well described, yet existing surveillance systems have not made adequate use of age-specific data. monitoring influenza-related morbidity using electronic health data may provide timely and detailed insight into the age-specific course, impact and epidemiology of seasonal drift and reassortment epidemic viruses. the purpose of this study was to evaluate the use of emergency departm ...200717683196
respiratory syncytial virus infection in elderly and high-risk adults.respiratory syncytial virus (rsv) is an increasingly recognized cause of illness in adults. data on the epidemiology and clinical effects in community-dwelling elderly persons and high-risk adults can help in assessing the need for vaccine development.200515858184
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