Publications

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developmental effect of the xmni site on ggamma-globin gene expression among newborn hb f-malta-i [ggamma117(g19)his-->arg, cat-->cgt] heterozygotes and adult beta+ -thalassemia homozygotes.hb f-malta-i [ggamma117(19)his-->arg, cat-->cgt] is a stable and benign variant of hb f found in 1.8% of maltese newborn. we studied 120 hb f-malta-i heterozygotes and four hb f-malta-i homozygotes. the mean proportion of ggamma-f-malta-i in hb f was 0.26 +/- 0.03 for the hb f-malta-i heterozygotes and 0.58 +/- 0.06 for the hb f-malta-i homozygotes. the hb f-malta-i allele was shown to occur on a background of the common mediterranean haplotype va [+ + - - - - - + + -]. furthermore, the common m ...200717365007
the role of atopy in maltese patients with chronic rhinitis.the global prevalence of allergic rhinitis has been on the increase and recent clinical experience in malta has shown a similar trend. the aim of this study was to investigate the role of atopy in 415 patients presenting with rhinitis of at least 3 months duration, and to identify the common allergens responsible. presenting clinical features, past and family history of seasonal allergic symptoms, exposure to cigarette smoking, pet ownership and occupation were analysed. all patients were skin t ...200415142070
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