Publications

a brief introduction to a nation-wide sampling survey on schistosomiasis.	a nation-wide sampling survey using a stratified group randomized sampling technique was conducted in 1989 in 8 provinces where schistosomiasis was still endemic. among 343 sampling spots, 197 were in controlled areas and 146 in endemic areas. 16,953 (10.2%) of 165,834 persons were found infected according to stool examination in the endemic areas with a population of 1.03% of the total in china. the positive rates of stool examination in hunan, hubei, jiangxi, anhui, jiangsu, zhejiang, yunnan a ...	1993	8222904
the effect of a combined approach to schistosomiasis control on the transmission of schistosoma japonicum in xingzi of poyang lake area, china.	the impact of a combined approach to schistosomiasis control from 1987 to 1989 and mass chemotherapy from 1992 to 1994 was studied in a rural community in xingzi county in the northwest corner of poyang lake in jiangxi province, china. humans, cattle, buffalo and pigs were known potential reservoirs of schistosoma japonicum. transmission occurs during water contact on and around seasonally flooded marshes that are used for grazing, the harvesting of grass and fishing. humans and livestock underw ...	1996	9185265
a baseline study on the importance of bovines for human schistosoma japonicum infection around poyang lake, china.	we hypothesize that bovine infections are responsible for the persistence of human schistosomiasis transmission in the yangtze marshlands of china. to test this hypothesis, we are carrying out a comparative intervention among four administrative villages in the poyang lake region, jiangxi province, two of which are experimental and two are control. the primary design involves treating, at the onset of the study, all the inhabitants in all four villages with praziquantel and all the bovines in tw ...	2001	11693868
a baseline study of importance of bovines for human schistosoma japonicum infections around poyang lake, china: villages studied and snail sampling strategy.	an epidemiologic survey among four administrative villages around poyang lake, in jiangxi province, china (two experimental and two controls) is being conducted to determine if bovine infections are responsible for the persistence of human schistosomiasis transmission on yangtze river marshlands. a previously published paper presented the experimental design and baseline data for humans and bovines. this paper presents basic data for the four villages using remote sensing, and baseline data for ...	2002	12164289
mathematical modelling of schistosomiasis japonica: comparison of control strategies in the people's republic of china.	we present the first mathematical model on the transmission dynamics of schistosoma japonicum. the work extends barbour's classic model of schistosome transmission. it allows for the mammalian host heterogeneity characteristic of the s. japonicum life cycle, and solves the problem of under-specification of barbour's model by the use of chinese data we are collecting on human-bovine transmission in the poyang lake area of jiangxi province in china. the model predicts that in the lake/marshland ar ...	2002	12020899
[impact of a reservoir project on schistosomiasis transmission in lake region].	to determine the impact of a project of building dike for storing water on schistosomiasis transmission in junshan lake.	2003	12884579
an economic evaluation of the national schistosomiasis control programme in china from 1992 to 2000.	the world bank loan project, by far the largest effort in china for schistosomiasis control since control activities were initiated in the mid 1950s, was carried out for a 9-year period commencing in 1992 in the 8 provinces where schistosoma japonicum remained endemic when the project started. to evaluate its impact, a retrospective economic evaluation was done in 2001. six representative counties, i.e. huarong in hunan province, qianjiang in hubei province, yugan in jiangxi province, tongling i ...	2005	16154104
a cluster-randomized bovine intervention trial against schistosoma japonicum in the people's republic of china: design and baseline results.	we describe the design and report baseline results of a cluster-randomized intervention to determine the importance of bovines for schistosoma japonicum transmission in southern china. the study involves four matched village pairs in hunan and jiangxi provinces, with a village within each pair randomly selected as intervention (human and bovine praziquantel treatment) or control (human praziquantel treatment only). total study population prevalences at baseline were 12.4% (n = 5,390) and 15.2% ( ...	2007	17984344
transmission dynamics of schistosoma japonicum in the lakes and marshlands of china.	schistosoma japonicum is a major public health concern in china, with over one million people infected and another 40 million living in areas at risk of infection. unlike the disease caused by s. mansoni and s. haematobium, schistosomiasis japonica is a zoonosis, involving a number of different mammalian species as reservoir hosts. as a result of a number of published reports from china, it has long been considered that bovines, particularly water buffaloes, play a major role in human s. japonic ...	2008	19115007
a strategy to control transmission of schistosoma japonicum in china.	schistosoma japonicum causes an infection involving humans, livestock, and snails and is a significant cause of morbidity in china.	2009	19129526
a cluster-randomised intervention trial against schistosoma japonicum in the peoples' republic of china: bovine and human transmission.	zoonotic schistosomiasis japonica is a major public health problem in china. bovines, particularly water buffaloes, are thought to play a major role in the transmission of schistosomiasis to humans in china. preliminary results (1998-2003) of a praziquantel (pzq)-based pilot intervention study we undertook provided proof of principle that water buffaloes are major reservoir hosts for s. japonicum in the poyang lake region, jiangxi province.	2009	19521532
mathematical modelling and control of schistosomiasis in hubei province, china.	hubei province, along with four other provinces in the central and eastern china where schistosomiasis is endemic (anhui, hunan, jiangsu, and jiangxi), is located in the lake and marshland regions along the yangtze river. high population density, large numbers of farm cattle, and huge areas of snail habitat are the main characteristics that maintain the persistence of the disease and the transmission of the parasite schistosoma japonicum in these regions. based on the schistosomiasis infection d ...	2010	20188689