Publications

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sero-epidemiological studies on coxiellosis in animals and man in the state of uttar pradesh and delhi (india).the prevalence of antibodies to coxiella burnetii, the causative agent of q-fever, was studied in domestic animals either at the farm or at the slaughter house and man in delhi and uttar pradesh (u.p.). evidence of q-fever infection was observed in 24.29% of 490 cattle, 16.79% of 536 sheep, 16.02% of 1011 buffaloes, 15.85% of 1937 goats, 14.67% of 184 pigs and 14.29% of 49 street dogs. twenty percent of 55 dairy cows, 9.52% of 21 dairy goats and 5.71% of 35 dairy buffaloes were found positive fo ...1979536122
sero-epidemiologic investigations on brucellosis in the states of uttar pradesh (u.p.) and delhi (india).sero-prevalence of brucellosis in man and animals was studied during the years 1976 and 1977. samples were collected from hospitals/slaughter houses/livestock farms located in delhi and different districts of uttar pradesh (u.p.). the sera samples tested were from 1685 men, 1607 goats, 438 sheep, 244 pigs, 361 cattle, 551 buffalos, 50 dogs, 318 equine and 43 free living animals. the percentage of seropositivity, excluding doubtful ones, was recorded as: man 0.89, goat 5.53, sheep 3.42, pigs 15.9 ...1979536123
a comparative study of urban and rural tetanus in adults.an analysis of 240 patients, aged 15+, admitted to the tetanus ward of irwin hospital, new delhi, with clinically diagnosed tetanus is reported. 134 patients (55.8%) came from rural areas and 106 (44.2%) from urban areas. the male--female ratio for both groups was approximately 2:1. rural patients were younger, showed a longer incubation period and experienced a lower crude case fatality rate. traditional practices like the application of cow dung to wounds, ear piercing and tatooing, and chroni ...1978681065
host feeding patterns of anopheles culicifacies species a and b.countercurrent immunoelectrophoresis was used to assay bloodmeals to determine the host specificity of anopheles culicifacies species a and b, collected from areas in delhi, uttar pradesh and bihar. results indicated the predominantly zoophagic nature of species a and b with a relatively higher degree of anthropophagy for species a. further, the human blood index was found to be related to the proportion of human and cattle population in an area. this study is significant because, of the two spe ...19883199114
antibody against coxiella burnetti in animals and humans in delhi. 19873502628
a sero-epidemiological study of brucellosis among workers of veterinary hospitals and slaughter house of union territory of delhi.in the sero-epidemiological study in union territory of delhi. sera from 148 veterinary workers and fifty healthy individuals were examined. of the serum samples collected from veterinary workers 41 (27.7%) showed a titre of 80.i.u./ml for brucella agglutinins. among positive individuals 9 (22%) exhibited clinical features. the highest sero-positivity was recorded in veterinary compounders (51.4%) followed by veterinary assistant surgeons (40%). agewise positivity was found to be maximum (37.3%) ...19853932249
serologic evidence of coxiella burnetii infection in domestic animals in delhi and surrounding areas. 19715167222
lactose intolerance in north and south indians.a multicenter study was carried out in india to determine the incidence of lactose intolerance in healthy volunteers from different parts of the country. the incidence was found to be 66.6% in the subjects from two south indian centers at trivandrum and pondicherry. in contrast, the incidence in the subjects from a north indian center in new delhi was much lower, i.e., 27.4% (p less than 0.001). the lower incidence in the north indian subjects may perhaps be due to the fact that they are descend ...19817234720
characterization of the g serotype and genogroup of new delhi newborn rotavirus strain 116e.we recently reported that the culture-adapted neonatal rotavirus strain 116e represented the first p type 11 human rotavirus, based on the close relationship of its vp4 protein to that of the bovine serotype g10p11 strain b223. in this study, we demonstrated by sequence analysis and cross-neutralization studies that the vp7 protein of 116e is closely related to those of the human serotype g9 strains, f45 and wi61, but distinct from b223 and other rotaviruses. low-level cross-neutralization was a ...19938212599
similarity of the vp4 protein of human rotavirus strain 116e to that of the bovine b223 strain.rotavirus strain 116e was isolated from the fecal specimen of a newborn infant from new delhi who had no symptoms of diarrhea. the strain could not be p typed using the pcr method recently developed in our laboratory so we have sequenced the 4th gene segment that encodes the vp4 protein using viral transcript rna prepared in vitro. this gene is 2353 base pairs in length and codes for a protein 772 amino acids long which begins with a methionine initiation codon at nucleotides 11 to 13 and ends w ...19938386888
lead in blood and milk from urban indian cattle and buffalo.lead levels were estimated in blood and milk collected from cattle and buffalo in 3 urban areas in india. mean blood lead concentrations were above background levels. the highest mean blood lead was from delhi/ghaziabad (0.43 +/- 0.06) where 11.11% of the samples contained 0.80 ppm lead. mean milk lead concentrations were 0.28 +/- 0.06 ppm in ahmedabad, 0.28 +/- 0.05 ppm in calcutta and 0.27 +/- 0.05 ppm in delhi. more than 50% of the milk samples from these areas had higher lead concentrations ...19958592841
sandfly survey in nainital and almora districts of uttaranchal with particular reference to phlebotomus argentipes, vector of kala-azar.kala-azar continues to pose a major public health problem in bihar, west bengal and parts of eastern uttar pradesh in india causing great deal of morbidity and mortality. during 1998, several kala-azar cases from sub-himalayan region were treated in delhi hospitals. and a suspected focus of kala-azar was subsequently reported from this area. therefore a preliminary sandfly survey was carried out during october, 1999 in 18 randomly selected villages at different altitudes in nainital & almora dis ...200111898464
molecular epidemiology of rotaviruses in india.rotaviruses cause an estimated 140 million cases of gastroenteritis and 800,000 deaths in children between the ages of 6 months to 2 yr in developing countries. in india, one of every 250 children or about 100-150,000 children die of rotavirus diarrhoea each year. the prevalence of rotavirus diarrhoea in india has been found to vary from 5-71 per cent in hospitalized children <5 yr of age with acute gastroenteritis. the seasonal variation of rotavirus diarrhoea in india varies in different geogr ...200314680200
accidental ligature strangulation deaths in east delhi (india).ligature strangulations are usually homicidal. accidental cases are quite uncommon, especially among adults. a retrospective ten-year study conducted in east delhi revealed that in a total of 98 cases of death due to strangulation, five cases (approximately 5%) among all medico-legal deaths were of fatal ligature strangulation, involving adults who were neither intoxicated nor indulging in paraphiliac activity. the causative agent in three cases was a cycle rickshaw, in one case it was a rotator ...200515745273
development of candidate rotavirus vaccines derived from neonatal strains in india.the need for a rotavirus vaccine in india is based on the enormous burden associated with the >100,000 deaths due to rotavirus diarrhea that occur annually among indian children. two rotavirus strains identified during nosocomial outbreaks of rotavirus infection in new delhi and bangalore, india, more than a decade ago are being developed as live oral vaccines. infected newborns had no symptoms, shed virus for up to 2 weeks after infection, mounted a robust immune response, and demonstrated prot ...200516088802
methane and nitrous oxide emission from bovine manure management practices in india.we report seasonal variation in ch(4) and n(2)o emission rate from solid storage of bovine manure in delhi as well as emission factors and emission inventory from manure management systems in india. emission flux observed in the year 2002-2003 was 4.29+/-1, 4.84+/-2.44 and 12.92+/-4.25 mg ch(4)kg(-1)dung day(-1), as well as 31.29+/-4.93, 72.11+/-16.22 and 6.39+/-1.76 microgn(2)o kg(-1)dung day(-1) in winter, summer and rainy seasons, respectively. ch(4) emission factors varied from 0.8 to 3.3 kg ...200716935398
knowledge, attitude and practices about animal bites and rabies in general community--a multi-centric study.rabies a disease as old as our civilization, continues to be the most feared of all communicable diseases. despite the availability the state-of-the-art tools which ensure near cent percent protection against rabies, india is the largest contributant to rabies mortality in the world. a multicentric study was carried out from april 2001 to september 2002 with the objective of assessing the knowledge, attitudes, beliefs and practices (kap) about animal bites and rabies in the general community. th ...200617913213
genotype profiles of mycobacterium avium subspecies paratuberculosis isolates recovered from animals, commercial milk, and human beings in north india.to understand the genetic diversity of mycobacterium avium subspecies paratuberculosis (map) isolates recovered from domestic and wild ruminants, commercial milk, and human beings in north india.200919233699
impact of domestic air pollution from cooking fuel on respiratory allergies in children in india.this study undertaken in india was aimed at identifying the effects of the indoor air pollutants so2, no2 and total suspended particulate mater (spm) generated from fuel used for cooking on respiratory allergy in children in delhi. a total of 3,456 children were examined (59.2% male and 40.8% female). among these, 31.2% of the children's families were using biomass fuels for cooking and 68.8% were using liquefied petroleum gas. levels of indoor so2, no2 and spm, measured using a handy air sample ...200819317340
presence, characterization, and genotype profiles of mycobacterium avium subspecies paratuberculosis from unpasteurized individual and pooled milk, commercial pasteurized milk, and milk products in india by culture, pcr, and pcr-rea methods.mycobacterium avium subspecies paratuberculosis (map) causes johne's disease in ruminants, a chronic enteritis evocative of human inflammatory bowel disease. in industrialized countries map has been cultured from pasteurized milk, compounding the increasing concern that map may be zoonotic. the purpose of this study was to evaluate commercially available unpasteurized and pasteurized milk and its products for the presence of viable map or map dna from an area of northern india with a population ...201019576834
genomic characterization of nontypeable rotaviruses and detection of a rare g8 strain in delhi, india.in the present investigation we molecularly characterized nontypeable rotavirus strains previously identified during surveillance in new delhi, india. the majority of strains were demonstrated to belong to genotype g1 (54.5%) or p[8] (77.8%) on the basis of nucleotide sequencing of fragments from their vp7 and vp4 genes. the other genotypes detected included g2, g8, g9, g12, and p[4]. a g8p[6] strain, strain ds108, was detected for the first time in northern india. the vp7 gene of ds108 was most ...200919794047
detection of new delhi metallo-beta-lactamase and extended-spectrum beta-lactamase genes in escherichia coli isolated from mastitic milk samples.in this study, eight escherichia coli isolates were obtained from milk samples of dairy cattle suffering from clinical/subclinical mastitis. isolates were characterized for antimicrobial resistance traits and virulence genes. results revealed that one isolate was harbouring new delhi metallo-beta-lactamase gene (blandm ). cloning and sequencing of the pcr amplicon confirmed the identity of the gene (genbank accession no. kc769583) having 100% homology with blandm-5 (genbank accession no. jn10459 ...201323870003
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