Publications

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a six-snp haplotype of adam33 is associated with asthma in a population of cartagena, colombia.a disintegrin and metalloprotein-33 (adam33) participates in the bronchial remodeling process in asthma, and genetic analyses pointed it out as a candidate gene in asthma.201019940503
association of g-protein-coupled receptor 154 with asthma and total ige in a population of the caribbean coast of colombia.g protein-coupled receptor 154 was described as an asthma susceptibility gene by positional cloning. it has been subsequently associated with asthma and other inflammatory diseases in several populations with different ethnic origin. replication of associations adds reliability to these findings.200919624525
sensitization to mite allergens and acute asthma in a tropical environment.the objective of this study was to determine whether sensitization to certain aeroallergens is associated with acute asthma in cartagena, colombia. ninety-nine subjects with acute asthma and 100 controls evaluated for other reasons were studied at a local emergency room. sensitization was established by specific ige determinations. statistically significant differences between asthmatic subjects and controls were found in the prevalence of specific ige to dermatophagoides pteronyssinus, 64.6% vs ...19989827423
mite fauna, der p i, der f i and blomia tropicalis allergen levels in a tropical environment.fifty dust samples were collected from the mattresses and bedroom floors of 25 subjects with allergic asthma in cartagena, colombia, in order to identify house dust mites and quantitate der p i, der f i and blomia tropicalis allergens. the geometric mean of the total mite density per gram of dust was 418 (range, 40-2280). twenty-two samples (44%) had more than 500 mites and four, less than 100. b. tropicalis and dermatophagoides pteronyssinus were found in 96% and 90% of the samples, accounting ...19938319126
mite allergy in the tropics: sensitization to six domestic mite species in cartagena, colombia.sensitization to the domestic mites blomia tropicalis, chortoglyphus arcuatus, lepidoglyphus destructor and aleuroglyphus ovatus was investigated in 77 subjects with clinical symptoms of asthma and/or allergic rhinitis and a positive skin prick test (wheal > or = 3 mm) to dermatophagoides pteronyssinus and/or d. farinae. seventy patients were skin test-positive to d. pteronyssinus and 73 to d. farinae. serum samples from 29 nonallergic, skin test-negative individuals were used as negative contro ...19938281353
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