Publications

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[biological studies of st. louis encephalitis virus in majé, bayano]. 19846149603
transmission of hepatitis a virus among recently captured panamanian owl monkeys.the presence of antibody to hepatitis a virus (anti-hav) in 60% of procured owl monkeys (aotus trivirgatus) held within the united states prompted a study of recently captured a trivirgatus in panama. only 2 of 145 newly captured monkeys, but all of 35 a trivirgatus held within a colony for over 100 days, were found to have anti-hav. of 41 sero-negative, newly captured monkeys followed prospectively, 25 became infected with hepatitis a virus (hav) as evidenced by seroconversion or demonstration ...19826290600
hepatitis a virus among captive panamanian owl monkeys. 19816118799
the prevalence of trypanosomes and microfilariae in panamanian monkeys.a total of 3,523 wild caught monkeys from panama was examined for blood parasites from august 1968 through june 1972. trypanosomes or microfilariae were observed in the blood of 31.1% of the monkeys. mixed infections, with microfilariae and trypanosomes, were detected in 6.6% of the animals. trypanosoma cruzi was found in marmosets. saguinus geoffroyi (12.2%), in white-faced capuchins, cebus capucinus (5.0%), in squirrel monkeys, saimiri sciureus (1.7%) and in black spider monkeys, ateles fuscic ...19744217567
studies on human malaria in aotus monkeys. iv. development of plasmodium falciparum in two subspecies of aotus trivirgatus. 19744132255
comparison of plasmodium falciparum infections in panamanian and colombian owl monkeys.parameters of blood-induced infections of the vietnam oak knoll, vietnam smith, and uganda palo alto strains of plasmodium falciparum studied in 395 panamanian owl monkeys in this laboratory between 1976-1984 were compared with those reported from another laboratory for 665 colombian owl monkeys, studied between 1968-1975, and, at the time, designated aotus trivirgatus griseimembra. the virulence of these strains was less in panamanian than in colombian owl monkeys, as indicated by lower mortali ...19853914842
adaptation of the panama ii strain of plasmodium falciparum to panamanian owl monkeys.the panama ii strain of plasmodium falciparum, acquired at the second passage level in splenectomized colombian owl monkeys, was adapted to owl monkeys of panamanian origin. patent infections were induced in 22 of 27 unaltered and 20 of 21 splenectomized recipients during 19 serial passages. the infections were significantly more virulent in splenectomized than normal panamanian owl monkeys, however recrudescences in seven normal monkeys achieved peak parasitemias 48 times greater than in the pr ...19873310680
infrequency of gross skin lesions among panamanian forest mammals with cutaneous leishmaniasis.natural leishmanial infections among feral mammals in the republic of panama were studied in relation to gross skin alterations. three dermatotropic species of leishmania, l. braziliensis, l. mexicana and l. hertigi, isolated from 230 sylvatic animals of 5 mammalian orders were involved. in 205 (89%) of the cases there were no gross skin alterations. cryptic infections of all three leishmanial species among wild animals were confirmed by culture and hamster inoculation. this type of infection wa ...19751178222
epidemiological patterns of cutaneous leishmaniasis in panama. iii. endemic persistence of the disease.endemic persistence of cutaneous leishmaniasis is described in el aguacate, a community established in the forest of central panama about 75 years ago. physiographic pecularities partially isolate el aguacate from other villages in the region. some of the original forest environment has been preserved and man-biting species of phlebotomine sandflies were abundant as was the two-toed sloth, choloepus hoffmanni, the principal reservoir host of leishmania braziliensis in panama. the inhabitants, as ...1976816214
susceptibility of owl monkeys to plasmodium falciparum infection in relation to location of origin, phenotype, and karyotype.the relationship among geographic origin, phenotype, karyotype, and susceptibility of owl monkeys to 2 strains of plasmodium falciparum was investigated. owl monkeys from columbia and panama were both susceptible to fatal infections with the asian fvo (vietnam-oak knoll) strain of p. falciparum. however, when inoculated with the african fup (uganda-palo alto) strain, most colombian owl monkeys developed fatal or potentially fatal (bled out with parasitemias of over 25%) infections, but panamania ...1979109608
comparative mitogen responses of lymphocytes from colombian panamanian, and peruvian owl monkeys.a comparative study of lymphocyte responses to various mitogens, an index of cell-mediated immune competency, was made under various culture conditions using peripheral blood lymphocytes from colombian, panamanian, and peruvian aotus monkeys. dose response curves were determined for each primate group to phytohemagglutinin, concanavalin a, and pokeweed mitogen stimulation. considerable variation in mitogen response was observed. the influence of culture media supplemented with fetal calf serum o ...1978102870
banding patterns of the chromosomes of two new karyotypes of the owl monkey, aotus, captured in panama.two new chromosome complements of aotus trivirgatus griseimembra are described making a total of five different karyotypes observed in this subspecies inhabiting panama and the northwestern part of colombia, south america. detailed comparisons of the g-banded chromosomes of these five karyotypes suggest that the polymorphism of chromosome numbers 56 and 55 in panamanian aotus and 54, 53, and 52 in colombian aotus stems primarily from a robertsonian translocation mechanism involving pairs b13 and ...1978101668
susceptibility of panamanian aotus lemurinus lemurinus to sporozoite-induced plasmodium falciparum (santa lucia) infection.aotus monkeys are good models for erythrocyte-induced plasmodium falciparum and p. vivax infections and have been extensively used in malarial drug and vaccine development. recently, it has been shown that certain species of aotus can be infected with sporozoites, and that the degree of susceptibility varies among species. we demonstrate here that panamanian aotus lemurinus lemurinus are susceptible to a sporozoite-induced infection, opening the possibility that this species of aotus could be us ...199910432049
adaptation of a nigerian strain of plasmodium falciparum to panamanian aotus trivirgatus.a patent infection (more than 190 days duration) with plasmodium falciparum, obtained directly from a patient who had been exposed to malaria in nigeria, was established in a splenectomized panamanian owl monkey, aotus trivirgatus griseimembra. subinoculations from the original monkey recipient into one splenectomized and two normal a. t. griseimembra produced primary patient parasitemias of 18-54 days duration. these results represent the first successful adaptation of p. falciparum from man to ...19817011068
studies on the cambodian i strain of plasmodium falciparum in aotus monkeys.the cambodian i strain of plasmodium falciparum, originally from kampuchea was adapted for development in three different types of aotus monkeys. high-level parasitemias were readily produced in splenectomized colombian a. trivirgatus griseimembra monkeys. initially, only minimal parasitemias developed in a. t. trivirgatus monkeys from colombia. however, in one animal, adaptation occurred and high-level parasitemias were obtained during the second recrudescence of the infection. passage to other ...19826752366
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