| genetic diversity analysis of macaca thibetana based on mitochondrial dna control region sequences. | macaca thibetana is a threatened primate species endemic to china. genetic diversities based on a 476-bp fragment at the 5'-end of the mitochondrial dna control region hvsi were assessed. haplotype diversity is high (0.8521), but nucleotide diversity among all haplotypes is only 0.0574. no haplotype was shared between sichuan (sc) and huangshan mountain (hs) populations. phylogenetic trees, analysis of molecular variance and network analysis consistently indicated that the sc and hs populations ... | 2008 | 19489138 |
| identification of mhc class i sequences in four species of macaca of china. | tibetan macaques (macaca thibetana), stump-tailed macaques (m. arctoides), assamese macaques (m. assamensis), and northern pig-tailed macaques (m. leonina) are four major species of macaca in china. in order to effectively use these species in biomedical research, thorough investigations of their mhc immunogenetics are required. in this study, we identified mhc class i sequences using cdna cloning and sequencing on a cohort of six m. thibetana, three m. arctoides, three m. assamensis, and three ... | 2013 | 24045838 |
| identification and characterization of the major histocompatibility complex class ii dqb (mhcmath-dqb1) alleles in tibetan macaques (macaca thibetana). | tibetan macaque (macaca thibetana), an endangered primate species endemic to china, have been used as experimental animal model for various human diseases. major histocompatibility complex (mhc) genes play a crucial role in the susceptibility and/or resistance to many human diseases, but little is known about tibetan macaques. to gain an insight into the mhc background and to facilitate the experimental use of tibetan macaques, the second exon of mhc-dqb1 gene was sequenced in a cohort of wild t ... | 2013 | 23745600 |
| genetic variation between two tibetan macaque (macaca thibetana) populations in the eastern china based on mitochondrial dna control region sequences. | tibetan macaque (macaca thibetana) is a threatened primate species endemic to china. population genetic and phylogenetic analyses were conducted in 66 tibetan individuals from sichuan (sc), huangshan (hs), and fujian (fj) based on a 477-bp fragment of mitochondrial dna control region. four new haplotypes were defined, and a relatively high level of genetic diversity was first observed in fj populations (hd = 0.7661). notably, a continuous approximately 10 bp-fragment deletion was observed near t ... | 2013 | 23245428 |
| [polymorphic analysis of mhc-dpb1 gene exon 2 in tibetan macaques (macaca thibetana)]. | major histocompatibility complex (mhc) molecules play an important role in the susceptibility and/or resistance to many diseases. to gain an insight into the mhc background of the tibetan macaques (macaca thibetana), and thereby facilitate their protection and application in biomedical research, the second exon of the mhc-dpb1 genes from 70 tibetan macaques in sichuan province were characterized by pcr, cloning, sequencing, and statistical analysis. a total of 18 mhc-dpb1 alleles were identified ... | 2012 | 23208139 |