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individual venom variability in the south american rattlesnake crotalus durissus cumanensis.crotalus durissus cumanensis snake venoms from different venezuelan regions, showed biochemical and hemostatic variations. fibrino(geno)lytic, hemorrhagic and procoagulant activities and gel-filtration chromatography and sds-page profiles were analyzed. differences were observed in fibrinolytic activity: kallikrein-like amidolytic activity was highest in venoms of santa teresa, and margarita. lagunetica and carrizales venoms showed the maximum fibrin lysis. the highest hemorrhagic activity was s ...200717482229
intraspecies differences in hemostatic venom activities of the south american rattlesnakes, crotalus durissus cumanensis, as revealed by a range of protease inhibitors.crotalus durissus cumanensis is an endemic rattlesnake found in venezuela and colombia. in this study, a comparative analysis of hemorrhagic, coagulation and fibrino(geno)lytic activities in the presence or absence of protease inhibitors was performed with venoms of the same species crotalus durissus cumanensis, from seven geographical regions of venezuela (lagunetica, santa teresa, carrizales, guarenas, anzoátegui, margarita and maracay). lagunetica, carrizales and anzoátegui venoms induced hem ...200818685436
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