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serratia marcescens endocarditis: a regional illness associated with intravenous drug abuse.from 1969 to 1974, 19 cases of serratia marcescens endocarditis were observed in the san francisco bay area. seventeen patients were intravenous drug users, and serratia caused 14% of all addict-associated endocarditis in san francisco. serratia strains were nonpigmented and had typical antibiotic sensitivities, except that 9 of the isolates exhibited colonial variation, with each variant having different antibiotic sensitivities. aortic or mitral valves were involved in 13 patients, and heart f ...19761106290
serratia endocarditis. a follow-up report.seventeen new cases of serratia marcescens endocarditis observed in the san francisco bay area since june 1974 are presented. fifteen patients had a history of illicit intravenous drug use and four patients had prosthetic heart valves. seven patients with infection of right-sided heart valves did well, although surgery was required in two for persistent fever or recurrent pulmonary emboli. only three of ten patients with left-sided infection survived despite synergistic antibiotic combinations a ...19806986128
phenotypic and molecular characteristics of carbapenem-resistant enterobacteriaceae in a health care system in los angeles, california, from 2011 to 2013.carbapenem-resistant enterobacteriaceae (cre) are a concern for health care in the united states but remain relatively uncommon in california. we describe the phenotype, clonality, and carbapenemase-encoding genes present in cre isolated from patients at a californian tertiary health care system. cre for this study were identified by evaluating the antibiograms of enterobacteriaceae isolated in the ucla health system from 2011 to 2013 for isolates that were not susceptible to meropenem and/or im ...201425210072
patient factors contributing to the emergence of gentamicin-resistant serratia marcescens.one hundred forty nosocomial serratia marcescens infections (including 76 cases of bacteremia) were identified by prospective surveillance from 1975 through 1977 and retrospective chart review from 1968 through 1974. thirty-four cases (24 per cent) involved gentamicin-resistant strains. all gentamicin-resistant strains appeared after 1974. ninety per cent of the patients had undergone surgery, and 88 per cent had received prior antimicrobial therapy. the emergence of gentamicin-resistant s. marc ...1979373434
gentamicin-resistant pseudomonas aeruginosa and serratia marcescens in a general hospital.from aug. 1, 1974, to july 31, 1975, inclusive, 19-1% of pseudomonas aeruginosa and 50-0% of serratia marcescens isolates from a general hospital were gentamicin resistant as determined by standardised disc testing; 80% of 118 different clinical isolates showed minimum inhibitory concentrations larger than or equal to 16 mug/ml of gentamicin in agar-dilution testing. all gentamicin-resistant s. marcescens and 79% of ps. aeruginosa isolates were susceptible to amikacin, while tobramycin and sisom ...197655850
the prevalence of antibiotic-resistant bacteria (arb) in waters of the lower ballona creek watershed, los angeles county, california.screening for the prevalence of antibiotic-resistant bacteria (arb) was done at the ballona creek and wetlands, an urban-impacted wetland system in los angeles, california. the goals were (1) to assess the overall prevalence of arb, and (2) compare differences in arb abundance and the types of antibiotic resistance (ar) among the following sample types: lagoon water from del rey lagoon, urban runoff from ballona creek, and water from the ballona wetlands (tidal water flooding in from the adjacen ...201728488226
a multistate outbreak of serratia marcescens bloodstream infection associated with contaminated intravenous magnesium sulfate from a compounding pharmacy.in contrast to pharmaceutical manufacturers, compounding pharmacies adhere to different quality-control standards, which may increase the likelihood of undetected outbreaks. in 2005, the centers for disease control and prevention received reports of cases of serratia marcescens bloodstream infection occurring in patients who underwent cardiac surgical procedures in los angeles, california, and in new jersey. an investigation was initiated to determine whether there was a common underlying cause.200717682984
trends in the etiology of infectious corneal ulcers at the f. i. proctor foundation.we analyzed laboratory results from corneal ulcers seen from 1976 to 1999 at the francis i. proctor foundation, a referral center in san francisco, to determine the relative frequencies of pathogens and to analyze for trends in frequencies of the most common pathogens. the results were compared with a previous study of corneal ulcers seen from 1948 to 1976 at the same institution.200415097130
sme-type carbapenem-hydrolyzing class a beta-lactamases from geographically diverse serratia marcescens strains.three sets of carbapenem-resistant serratia marcescens isolates have been identified in the united states: 1 isolate in minnesota in 1985 (before approval of carbapenems for clinical use), 5 isolates in los angeles (university of california at los angeles [ucla]) in 1992, and 19 isolates in boston from 1994 to 1999. all isolates tested produced two beta-lactamases, an ampc-type enzyme with pi values of 8.6 to 9.0 and one with a pi value of approximately 9.5. the enzyme with the higher pi in each ...200011036019
microbiologic investigation of an epizootic of mastitis caused by serratia marcescens in a dairy herd.an epizootic of subclinical and clinical mastitis caused by serratia marcescens was investigated in a 1,000-cow dairy farm in california. serratia marcescens was isolated from 13 to 18% of composite milk samples obtained from lactating dairy cows. during monthly milk sampling performed during a 4-month period, s marcescens was isolated from 38.8 to 62.3% of composite milk samples obtained from cows from which s marcescens was previously isolated. few cows infected with s marcescens had evidence ...19921559873
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