clinical considerations and costs associated with formulary conversion from tobramycin to gentamicin.the clinical and financial effects of replacing tobramycin with gentamicin on the formulary of a 550-bed teaching hospital were studied. on the recommendation of the pharmacy and therapeutics committee, the formulary aminoglycoside was changed from tobramycin to gentamicin in june 1985; the nonformulary status of amikacin was unchanged. five weeks later, physician compliance was assessed and the reasons for prescribing nonformulary aminoglycosides were determined. two four-month-long evaluations ...19892719049
respiratory pathogen colonization of the dental plaque of institutionalized elders.although it has been established that aspiration of pharyngeal bacteria is the major route of infection in the development of nosocomial pneumonia, colonization of the pharyngeal mucosa by respiratory pathogens has been shown to be a transient phenomenon. it has been suggested that the dental plaque may constitute an additional, possibly more stable, reservoir of respiratory pathogens. the purpose of this study was to assess the prevalence of oral colonization by potential respiratory pathogens ...199910860077
molecular epidemiology of serratia marcescens outbreaks in two neonatal intensive care units.serratia marcescens can cause serious infections in patients in neonatal intensive care units (nicus), including sepsis, pneumonia, urinary tract infection, and conjunctivitis. we report the utility of genetic fingerprinting to identify, investigate, and control two distinct outbreaks of s. marcescens.200415484794
gram-negative bacilli associated with catheter-associated and non-catheter-associated bloodstream infections and hand carriage by healthcare workers in neonatal intensive care units.bloodstream infections caused by gram-negative bacilli are a substantial cause of morbidity and mortality in infants in neonatal intensive care units. this study describes the species of gram-negative bacilli causing bloodstream infections in two neonatal intensive care units, compares characteristics of catheter-related and non-catheter-related bloodstream infections, and compares species and antibiotic resistance patterns of these organisms with those isolated from the hands of nurses working ...200515982435
epidemiology of gram-negative conjunctivitis in neonatal intensive care unit describe the epidemiologic features, risk factors, and antibiotic susceptibilities for gram-negative conjunctivitis among neonatal intensive care unit (nicu) patients.200818378213
emergence of serine carbapenemases (kpc and sme) among clinical strains of enterobacteriaceae isolated in the united states medical centers: report from the mystic program (1999-2005).among 8885 enterobacteriaceae tested in the 1999 to 2005 period as part of the usa meropenem yearly susceptibility test information collection (mystic) program, 51 strains with increased imipenem and meropenem mic values (> or =2 microg/ml) were detected. bla(kpc) was identified from 28 klebsiella pneumoniae from 3 medical centers in the new york city area (8 ribotypes), 2 klebsiella oxytoca from arkansas (same ribotype), 7 citrobacter freundii (6 from new york [5 ribotypes] and 1 from delaware) ...200617020798
specific distribution of r factors in serratia marcescens strains isolated from hospital infections.serratia marcescens strains from three hospitals in the city of new york were tested for antibiotic susceptibility patterns and the presence of transmissible antibiotic resistance factors. there appears to be a pattern characteristic for each hospital with regard to the sensitivity to nalidixic acid, tetracycline, chloramphenicol, and sulfonamides, whereas the resistance to ampicillin, cephalothin, and streptomycin is similar in the strains isolated from all three hospitals. in one hospital, a s ...19714940874
bacteriologic contamination in an air-fluidized air-fluidized bed was found to be a potential bacteriologic hazard when used by heavily infected burned patients. even after following the manufacturer's protocol for eliminating bacteria from the bed and for cleaning the filter sheet, staphylococcus aureus, staphylococcus epidermidis, streptococcus fecalis, escherichia coli, and serratia marcescens were recovered. use of the bed was suspended until an effective disinfecting procedure was developed for the filter sheet and weekly removal of s ...19836339733
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