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nosocomial urinary tract infections: secular trends, treatment and economics in a university hospital.during a 71-month interval 3,024 nosocomial urinary tract infections were identified by prospective surveillance at our hospital. the annual attack rate varied between 2.0 and 3.1 per 100 admissions. gram-negative bacilli caused 74 per cent of all urinary infections and recurrent infections in the hospital accounted for only 1 per cent. the most frequent pathogens were escherichia coli (24 per cent), pseudomonas aeruginosa (8 per cent), streptococcus faecalis (7 per cent), klebsiella pneumoniae ...19836864885
nosocomial klebsiella infection in a neonatal unit: identification of risk factors for gastrointestinal colonization.sequential outbreaks of infection due to gentamicin-resistant klebsiella pneumoniae (grkp) types 30 and 19 occurred in the neonatal intensive care unit (nicu) at the medical college of virginia in 1977 and 1978. the extensive epidemiologic investigation carried out included a case-control study, careful review of aseptic technique, and cultures from nursery staff and environment. the gastrointestinal (gi) tracts of the patients were the reservoirs for grkp, and the epidemic strain was transmitte ...19807005139
epidemiology of conjugative plasmid-mediated ampc beta-lactamases in the united states.a sample of 752 resistant klebsiella pneumoniae, klebsiella oxytoca, and escherichia coli strains from 70 sites in 25 u.s. states and the district of columbia was examined for transmissibility of resistance to ceftazidime and the nature of the plasmid-mediated beta-lactamase involved. fifty-nine percent of the k. pneumoniae, 24% of the k. oxytoca, and 44% of the e. coli isolates transferred resistance to ceftazidime. plasmids encoding ampc-type beta-lactamase were found in 8.5% of the k. pneumon ...200414742206
notes from the field: carbapenem-resistant enterobacteriaceae producing oxa-48-like carbapenemases--united states, 2010-2015.carbapenem-resistant enterobacteriaceae (cre) are bacteria that are often resistant to most classes of antibiotics and cause health care-associated infections with high mortality rates. among cre, strains that carry plasmid-encoded carbapenemase enzymes that inactivate carbapenem antibiotics are of greatest public health concern because of their potential for rapid global dissemination, as evidenced by the increasing distribution of cre that produce the klebsiella pneumoniae carbapenemase and th ...201526633574
Carbapenem-resistant Klebsiella pneumoniae associated with a long-term--care facility --- West Virginia, 2009-2011.On January 27, 2011, a West Virginia county health department was notified of a cluster of carbapenem-resistant Klebsiella pneumoniae (CRKP) cases detected by a local hospital (hospital A). CRKP infections frequently are resistant to a majority of antimicrobial agents and have an increased risk for morbidity and mortality. The West Virginia Bureau for Public Health (WVBPH) conducted field investigations to identify all cases, characterize risk factors for infection, and abstract data for a match ...201122012114
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