| outbreak of colistin-resistant, carbapenem-resistant klebsiella pneumoniae in metropolitan detroit, michigan. | carbapenem-resistant klebsiella pneumoniae has spread worldwide and throughout the united states. colistin is used extensively to treat infections with this organism. we describe a cluster of colistin-resistant, carbapenem-resistant k. pneumoniae infection cases involving three institutions in detroit, mi. a cluster of five cases of colistin-resistant, carbapenem-resistant k. pneumoniae was identified at detroit medical center (dmc) from 27 july to 22 august 2009. epidemiologic data were collect ... | 2010 | 21115786 |
| regional dissemination of kpc-producing klebsiella pneumoniae. | production of a klebsiella pneumoniae carbapenemase (kpc) is the most common mechanism of carbapenem resistance in the united states; however, until now, kpc-producing isolates have not been found in western michigan. molecular typing of two kpc-producing k. pneumoniae isolates from michigan showed their similarity to other midwestern isolates. they were also unrelated to the dominant sequence type observed throughout the united states, multilocus sequence type 258. this could represent regional ... | 2009 | 19687250 |
| nosocomial infection among patients in different types of intensive care units at a city hospital. | available data on the characteristics of infections in different types of icus are limited. between may and july 1984, overall infection rates of patients in the icus and in the general wards at the detroit receiving hospital were 19.2% and 9.8%, respectively (p less than .001). specific infection rates (number of infections/100 admissions in each unit) were 35.2% for surgical unit, 29.8% for burn unit, 13.9% for medical unit, and 6.6% for coronary unit. of the total number of patients admitted, ... | 1986 | 3698616 |
| disease patterns in the detroit zoo: a study of the mammalian population from 1973 through 1983. | a retrospective study was conducted to evaluate disease patterns in the mammals at the detroit zoo from 1973 through 1983. the reindeer (rangifer tarandus), common eland (taurotragus oryx), rednecked wallaby (protemnodon rufogrisea), sitatunga (tragelaphus spekii), and kangaroo (macropus spp)- were the most frequently affected mammalian species. parasitic agents (80% of which were internal parasites) caused morbidity in 60.2% of the mammals evaluated (n = 2,475) and microbial agents caused morbi ... | 1985 | 3878354 |
| an outbreak of gentamicin-resistant klebsiella pneumoniae: analysis of control measures. | in april 1978, a strain of gentamicin-resistant klebsiella pneumoniae (grk) was introduced into the neonatal intensive care unit of henry ford hospital. an additional ten cases of grk occurred over the subsequent 16 months and intestinal colonization occurred in up to 91% of admissions per month. all grk were susceptible to amikacin and were capsular serotype 19. though hand contamination of hospital personnel with grk was documented, increased handwashing practices did not reduce colonization r ... | 1984 | 6365819 |
| major trends in the microbial etiology of nosocomial infection. | to determine trends in the microbial etiology of nosocomial infections in the 1980s, surveillance data on the microbiology of documented nosocomial infection reported to the national nosocomial infections surveillance system and from the university of michigan hospital were analyzed. antimicrobial susceptibility data on selected pathogens from both sources were also reviewed. overall, escherichia coli decreased from 23% of infections in 1980 to 16% in 1986-1989, klebsiella pneumoniae dropped fro ... | 1991 | 1928195 |
| outcomes and genetic relatedness of carbapenem-resistant enterobacteriaceae at detroit medical center. | background.ôçâcarbapenem-resistant enterobacteriaceae (cre) are rapidly emerging in hospitals in the united states and are posing a significant threat. to better understand the transmission dynamics and the acquisition of resistant strains, a thorough analysis of epidemiologic and molecular characteristics was performed. methods.ôçâcre isolated at detroit medical center were analyzed from september 2008 to september 2009. bla(kpc) genes were investigated by polymerase chain reaction (pcr), and r ... | 2011 | 21828966 |
| statewide surveillance of carbapenem-resistant enterobacteriaceae in michigan. | carbapenem-resistant enterobacteriaceae (cre) are clinically challenging, threaten patient safety, and represent an emerging public health issue. cre reporting is not mandated in michigan. | 2014 | 24602937 |
| plasmid profiles and klebocin types in epidemiologic studies of infections by klebsiella pneumoniae. | the epidemiological methods of klebocin typing, antibiogram and plasmid dna profile were evaluated using organisms isolated from a suspected epidemic of gentamicin-resistant klebsiella pneumoniae and unrelated strains from different geographical areas as controls. the electrophoretic analysis of plasmid dnas from klebsiella pneumoniae showed the presence of at least one and up to as many as seven plasmids in each strain. the molecular weight of plasmid dnas ranged from 1 to greater than 70 mega ... | 1988 | 3134232 |
| investigating the impact of the definition of previous antibiotic exposure related to isolation of extended spectrum β-lactamase-producing klebsiella pneumoniae. | previous antibiotic exposure is a risk factor for extended spectrum β-lactamase (esbl)-producing klebsiella pneumoniae isolation, but the optimal definition of previous antibiotic exposure remains unclear. | 2011 | 21255875 |