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[prevalence and susceptibility patterns of extended-spectrum betalactamase-producing escherichia coli and klebsiella pneumoniae in a general university hospital in beirut, lebanon].extended-spectrum betalactamases (esbls) are recognized worldwide as a problem in hospitalized patients. their prevalence among clinical isolates of enterobacteriaceae varies between countries and institutions. we studied the evolution of esbl production by clinical isolates of escherichia coli and klebsiella pneumoniae and analyzed the patterns of susceptibility of these isolates to different antimicrobial agents in a general university hospital in beirut. of the 4299 isolates of e. coli and 12 ...200312973463
epidemiology and risk factors for extended-spectrum beta-lactamase-producing organisms: a case control study at a tertiary care center in lebanon.infections caused by extended-spectrum beta-lactamase (esbl)-producing gram-negative bacilli constitute a growing problem worldwide. at the american university of beirut medical center (aubmc), we have observed a significant rise in the rates of esbl-producing organisms over the past 5 years.200516061138
isolation of the first metallo-beta-lactamase producing klebsiella pneumoniae in lebanon.a 58 year-old man was admitted to the saint joseph hospital-raymond and aida najjar polyclinic in beirut on july 17, 2007 to undergo surgery for a moderately differentiated colonic adenocarcinoma (t3n0). following several discharges and re-admissions, an extended spectrum beta-lactamase (esbl) producing escherichia coli susceptible to imipenem was isolated. the patient was put on imipenem and metronidazole. three weeks later, imipenem (imp) resistant klebsiella pneumoniae was isolated.200818509771
[evolution of susceptibility to antibiotics of escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa and acinetobacter baumanii, in a university hospital center of beirut between 2005-áand 2009.]introduction: until recently, multiresistant bacteria were only limited to hospitals. however, they are now responsible for community acquired infections, affecting people who have had no contact with the hospital environment. several mechanisms are associated with these resistances. the production of betalactamases is however the predominant mechanism and especially the production of extended spectrum beta-lactamases or esbl by strains of escherichia coli and klebsiella pneumoniae, which mediat ...201121719212
a reflection on bacterial resistance to antimicrobial agents at a major tertiary care center in lebanon over a decade.antimicrobial resistance has been inflecting deleterious health and economic consequences locally and globally. this study addresses the patterns and trends of bacterial resistance to antimicrobial agents over a decade, at a major tertiary care center in beirut.201423198452
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