| transmissible drug resistance in certain enteric bacilli isolated in tehran. | a total of 284 isolates of gram-negative enteric bacilli associated with urinary tract infections or normal fecal flora were examined for resistance to antimicrobial agents and the presence of transmissible r factors. klebsiella pneumoniae and proteus isolates exhibited the highest frequencies of resistance to antimicrobial agents. the incidence of drug resistance among clinical isolates of escherichia coli was considerably higher than its incidence among e. coli strains isolated from healthy in ... | 1981 | 7021077 |
| antibiotic-resistance patterns and frequency of extended-spectrum beta-lactamase-producing isolates of klebsiella pneumoniae in tehran. | extended-spectrum beta-lactamase (esbl)-producing strains of klebsiella pneumoniae have caused major therapeutic problems worldwide since the majority are resistant to various antibiotics. in this study, an investigation was conducted regarding antibiotic-resistant patterns of 128 isolates of k pneumonile cultured from iranian patients at two teaching hospitals during 2004-2005. | 2006 | 17072265 |
| distribution of tem and shv beta-lactamase genes among klebsiella pneumoniae strains isolated from patients in tehran. | there are numerous types of extended spectrum beta-lactamases (esbls), of which tem and shv are predominant among klebsiella pneumoniae strains. nosocomial infections with strains of k. pneumoniae are common in healthcare centers in iran. however, no information is available on the prevalence of different phenotypes of esbl strains in tehran hospitals. | 2007 | 17968291 |
| a survey on species and prevalence rate of bacterial agents isolated from cockroaches in three hospitals. | the presence of cockroaches has health implications, such as nosocomial infection, as the insects move freely from areas within and around hospitals that may harbor pathogenic organisms. the goals of the present study were to determine species of bacteria isolated from cockroaches found in three tehran hospitals, and to determine distribution of potential vectors by species and sex. the study is descriptive laboratory research. a total of 305 cockroaches from three species were trapped and ident ... | 2009 | 18973441 |
| bacteriuria by extended-spectrum beta-lactamase-producing escherichia coli and klebsiella pneumoniae: isolates in a governmental hospital in south of tehran, iran. | antibiotic resistant mutants producing extended-spectrum beta-lactamase (esbl) have emerged among escherichia coli and klebsiella pneumoniae. this study was done to determine the frequency of esbl-producing e coli and k pneumoniae species isolated from urine samples of our patients. | 2008 | 19377237 |
| distribution of bla(tem), bla(shv), bla(ctx-m) genes among clinical isolates of klebsiella pneumoniae at labbafinejad hospital, tehran, iran. | extended-spectrum beta-lactamase (esbl)-producing isolates of klebsiella pneumoniae have been increasingly recognized in the hospital settings in iran as well as throughout the world. the aim of this study was to detect and determine the genes encoding the esbls including bla(tem), bla(shv), and bla(ctx-m) groups among the k. pneumoniae isolates at labbafinejad hospital by polymerase chain reaction (pcr) and characterize them by direct sequencing of pcr products. eighty-nine isolates were isolat ... | 2010 | 19961397 |
| high prevalence of extended-spectrum beta-lactamase-producing klebsiella pneumoniae in a tertiary care hospital in tehran, iran. | extended-spectrum beta (beta)-lactamase (esbl)-producing enterobacteria are major emerging pathogens in nosocomial infections. | 2010 | 20351452 |
| genetic characterization of esbl producing strains of klebsiella pneumoniae from tehran hospitals. | this study was conducted to determine the genetic characterization of extended-spectrum beta-lactamase (esbl) producing strains of klebsiella pneumoniae isolated from iranian patients in hospitals in tehran. | 2010 | 21045352 |
| Molecular characterization of CTX-M ß-lactamases among Klebsiella pneumoniae isolated from patients at Tehran hospitals. | Plasmid-encoded CTX-M-group of extended-spectrum ß-lactamases (ESBLs) represent a significant and rapidly emerging problem in most part of the world. The aim of the present study was to describe the prevalence of CTX-M producing Klebsiella pneumoniae at Tehran hospitals. | 2011 | 21860105 |
| device-associated infection rates and bacterial resistance in six academic teaching hospitals of iran: findings from the international nocosomial infection control consortium (inicc). | device-associated health care-acquired infections (da-hais) pose a threat to patient safety, particularly in the intensive care unit (icu). however, few data regarding da-hai rates and their associated bacterial resistance in icus from iran are available. a da-hai surveillance study was conducted in six adult and pediatric icus in academic teaching hospitals in tehran using cdc/nhsn definitions. we collected prospective data regarding device use, da-hai rates, and lengths of stay from 2584 patie ... | 2015 | 26027477 |
| detection of acra, acrb, aac(6')-ib-cr, and qepa genes among clinical isolates of escherichia coli and klebsiella pneumoniae. | the distribution of drug resistance among clinical isolates of escherichia coli and klebsiella pneumoniae has limited the therapeutic options. the aim of this study was to report the prevalence of quinolone resistance genes among e. coli and k. pneumoniae clinical strains isolated from three educational hospitals of tehran, iran. | 2017 | 27936860 |
| distribution of virulence genes and genotyping of ctx-m-15-producing klebsiella pneumoniae isolated from patients with community-acquired urinary tract infection (ca-uti). | klebsiella pneumoniae is one of the most important agents of community-acquired urinary tract infection (ca-uti). in addition to extended-spectrum β-lactamases (esbls), a number of virulence factors have been shown to play an important role in the pathogenesis of k. pneumoniae, including capsule, siderophores, and adhesins. little is known about the genetic diversity and virulence content of the ctx-m-15-producing k. pneumoniae isolated from ca-uti in iran. a total of 152 k. pneumoniae isolates ... | 2016 | 27725280 |
| association between presence of virulence genes and antibiotic resistance in clinical klebsiella pneumoniae isolates. | to investigate the presence of rmpa and wcag virulence genes and class 1, 2, and 3 integrons, and to evaluate a relationship between antibiotic resistance and virulence in klebsiella pneumoniae methods: we collected a total of 200 k. pneumoniae isolates from hospitals in tehran, iran. antibiotic susceptibility was determined using the disk diffusion method. the extended-spectrum β-lactamase (esbl) producers were detected using the combination disk method. we detected the rmpa and wcag genes and ... | 2016 | 27498999 |
| successful international clones of blactx-m-15-producing klebsiella pneumoniae with coexpression of plasmid-mediated quinolone resistance (pmqr) determinants in tehran hospitals. | the dissemination of plasmid-mediated multidrug resistance in enterobacteriaceae is a major public health concern. we investigated the prevalence of plasmid-mediated quinolone resistance (pmqr), 16s rrna methylases, ctx-m, and acquired ampc enzymes in esbl-producing klebsiella pneumoniae (n=40) from tehran hospitals. plasmid replicon typing, pulsed-field gel electrophoresis (pfge), and multilocus sequence typing (mlst) were carried out for typing. ctx-m group 1 (confirmed as bla(ctx-m-15) in sel ... | 2015 | 26458278 |
| high rate of aminoglycoside resistance in ctx-m-15 producing klebsiella pneumoniae isolates in tehran, iran. | to determine the prevalence of extended-spectrum beta lactamases (esbls), the bla(ctx-m) genes, and aminoglycoside modifying enzymes genes in clinical isolates of klebsiella pneumoniae (k. pneumoniae). | 2014 | 25051075 |
| molecular characterization of carbapenem-resistant strains of klebsiella pneumoniae isolated from iranian patients: first identification of blakpc gene in iran. | multi-resistant klebsiella pneumoniae has been considered a serious global threat. this study was initiated to investigate carbapenem resistance among k. pneumoniae isolates in iran and to detect carbapenemases in resistant strains. from 2009 to 2012, 180 k. pneumoniae strains were collected from tehran hospitals. of the isolates, 42 isolates (23.3%) were resistant to meropenem, 29 isolates (16.1%) were resistant to ertapenem, and 14 isolates (7.7%) were resistant to imipenem. all of carbapenem- ... | 2014 | 24428238 |
| first report of new delhi metallo-beta-lactamase-1-producing klebsiella pneumoniae in iran. | new delhi metallo-beta-lactamase (ndm-1) is a novel metallo-beta-lactamase (mbl). sporadic cases of ndm-1 positive strains have been reported from different countries, suggesting a widespread dissemination. the aim of this study was the detection of mbls in enterobacteriaceae isolated from patients in tehran hospitals. after identification tests, the susceptibility to the antibiotics was done by kirby-bauer method and broth microdilution. carbapenem-resistant isolates were tested for carbapenema ... | 2013 | 22984942 |