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prevalence of anti-hepatitis c virus in the blood donor population of rio de janeiro.the prevalence of hepatitis c virus (hcv) antibodies in 2,557 asymptomatic volunteer brazilian blood donors is reported. using the line immunoassay (inno-lia) as a confirmatory test on elisa anti-hcv-positive reacting sera, a prevalence rate of 2.7% for anti-hcv positivity was found. by comparison, prevalences of 1.6% for hepatitis b surface antigen, 0.9% for treponema pallidum, 0.4% for human immunodeficiency virus and 0.04% for trypanosoma cruzi were observed. only 57% of the hcv-positive dono ...19937692672
prevalence and risk factors for hepatitis c antibodies in volunteer blood donors in brazil.little is known about the prevalence, risk factors, and transmission of hepatitis c virus (hcv) in a nontransfused population, particularly in developing countries.19948310484
viral hepatitis markers in antepartum and postpartum women in rio de janeiro, brazil.a seroprevalence study was carried out among a group of women in rio de janeiro to determine the prevalence of different markers for viral hepatitis given the limited data among healthy populations. blood samples collected and tested from 874 women before or after delivery in a public county maternity hospital demonstrated age to be directly related to markers for hepatitis a virus and hepatitis b virus (hbv) infection. the prevalence of hbv and hepatitis c virus infection were lower than that o ...200212016444
hemophilia care in the state of rio de janeiro, brazil.in the developing countries of the world, few people with hemophilia receive adequate care. nevertheless, brazil has made significant advances in the treatment of hemophilia over the last decade. the provision of factor concentrates imported by the government of brazil is gradually increasing, and patients receive the concentrates for free. a national register was established as well as a coordinated program for comprehensive care. of the 6 297 persons with hemophilia in brazil who were register ...200312744788
"the first shot": the context of first injection of illicit drugs, ongoing injecting practices, and hepatitis c infection in rio de janeiro, brazil.the context of first drug injection and its association with ongoing injecting practices and hcv (hepatitis c virus) infection were investigated. injection drug users (idus) (n = 606) were recruited in "drug scenes" (public places, bars) in rio de janeiro, brazil, interviewed, and tested for hcv. sharing of needles/syringes was more prevalent at the first injection (51.3%) than at the baseline interview (36.8%). those who shared syringes/needles at first injection were more likely to be currentl ...200616612439
antibody dynamics and spontaneous viral clearance in patients with acute hepatitis c infection in rio de janeiro, brazil.the anti-hcv antibody response has not been well characterized during the early phase of hcv infection and little is known about its relationship to the clinical course during this period.201121226945
prospective follow-up of patients with acute hepatitis c virus infection in brazil.the natural outcome of infection with hepatitis c virus (hcv) varies substantially among individuals. however, little is known about host and viral factors associated with a self-limiting or chronic evolution of hcv infection.201020235831
epidemiological and genetic analyses of hepatitis c virus transmission among young/short- and long-term injecting drug users from rio de janeiro, brazil.injecting drug users (idu) have a key role in hepatitis c virus (hcv) epidemiology. young/short-term idus constitute a target group for preventive/harm reduction interventions.200919195927
[high prevalence of genotype 1 in individuals with hepatitis c in belo horizonte, mg].the hepatitis c virus is characterized by significant genetic heterogeneity. it is currently classified into six main genotypes and several subtypes. determining the genotype of the virus is important in clinical practice for guiding the treatment for individuals with chronic hepatitis c. the prevalence of different genotypes and subtypes of the hepatitis c virus has not been fully studied in some regions of brazil. in this study, 788 samples from patients with chronic hepatitis c who were atten ...200818719801
seroprevalence of hepatitis b and c virus markers among blood donors in rio de janeiro, brazil, 1998-2005.the prevalence of infection by hepatitis b (hbv) and c (hcv) viruses varies among geographical regions. in order to determine the prevalence of hbv and hcv infection in voluntary blood donors we evaluated the prevalence of hbsag, anti-hbc, and anti-hcv markers of 128,497 blood donor samples collected from 1998 to 2005 in the state of rio de janeiro. these markers were analyzed by immunoenzymatic tests, as determined by the ministry of health. data were obtained from the sorology laboratory of th ...200617072482
prevalence of oral lichen planus in brazilian patients with hcv infection.the objective of this investigation was to assess the prevalence of oral lichen planus (olp) in brazilian patients infected with hepatitis c virus (hcv) from the state of rio de janeiro.200516122661
sexual behaviour and infection rates for hiv, blood-borne and sexually transmitted infections among patients attending drug treatment centres in rio de janeiro, brazil.a survey was carried out in 2 drug use treatment centres (tcs) in rio de janeiro, brazil, to assess risk behaviours, hiv infection and other sexually transmitted infections/blood-borne infections (stis/bbis). two hundred and twenty-five drug users (195 males and 30 females) were interviewed and clinically examined, and their blood and urine were tested for stis/bbis. prevalences (%) for these infections were as follows--hiv: 0.9, hepatitis b virus (hbv): 14.7, hepatitis c virus (hcv): 5.8, syphi ...200010872912
high prevalence of hepatitis c infection among brazilian hemodialysis patients in rio de janeiro: a one-year follow-up study.nearly 400 hemodialysis patients treated at 5 different hemodialysis units in rio de janeiro were tested for one year for the presence of hepatitis c and b markers. during the same period, samples were also obtained from 35 continuous ambulatory peritoneal dialysis (capd) patients and from 242 health care workers. depending on the hemodialysis unit studied, anti-hcv prevalence rates ranging from 47% to 82% (mean 65%) were detected. capd patients showed a lower prevalence of 17%. the prevalence o ...19957569645
prevalence of antibodies to hepatitis c virus in populations at low and high risk for sexually transmitted diseases in rio de janeiro.in order to investigate the sexual transmission of the hepatitis c virus (hcv), the prevalence of specific antibodies in populations at high and low risk for sexually transmitted diseases (stds) was evaluated. the population at low risk for stds was composed of persons who voluntarily donated blood at the hospital universitário clementino fraga filho (hucff) between july and november, 1990 (n = 2494). the population at high risk for stds was drawn from an ongoing study on the natural history of ...19937509022
early appearance and biphasic kinetics of igg antibody against hepatitis c virus protein c100-3.antibody to recombinant hepatitis c virus (hcv) protein c100 (anti-c100) was measured for a period of 6 months by enzyme immunoassay in nine prospectively followed non a-nonb (nanbh) cases which occurred after cardiac surgery at a hospital in rio de janeiro (brazil). at least seven cases were infected with hcv; four of these developed chronic hepatitis as shown in liver biopsy at the 6th month after transfusion. the first elevation of alanine aminotransferase (alt) occurred between 15 and 45 day ...19921312660
[prevalence of antibodies to hepatitis c (anti hcv) in blood donors in rio de janeiro, brazil. its relation to alt and anti hbc].we have studied 933 volunteer blood donors from may to july, 1990. after a interview and screening tests for syphilis, chagas disease, malaria and hiv, they underwent an enzyme immunoassay for hbsag, anti hbc and anti hcv antibodies. alanine aminotransferase (alt) serum levels were determined by auto analyser. most blood donors were male with mean age of 33 years (19-65). anti hcv prevalence was 3.1% (29 from 933 blood donors). among anti hcv+, blood donors, 44.8% (13/29) had alt 40 ui/l, 31% (9 ...19921307202
association of il-10, il-4, and il-28b gene polymorphisms with spontaneous clearance of hepatitis c virus in a population from rio de janeiro.cytokines play an important role in the regulation of the immune response. in hepatitis c virus (hcv) infection, cytokine levels may influence the outcome of acute hcv infection. polymorphisms in cytokine genes have been associated to different expression levels in response to infection. this study was carried out to investigate the association of several cytokine gene polymorphisms with disease outcome in hcv-infected patients.201222986179
low rates of sustained virologic response with peginterferon plus ribavirin for chronic hepatitis c virus infection in hiv infected patients in rio de janeiro, brazil.the standard treatment for chronic hepatitis c virus (hcv) infection in hiv-infected subjects is the combination of alfapeginterferon (peg-ifn) plus ribavirin. we designed this study to evaluate the rate of svr and predictors of svr in a public health setting in rio de janeiro, brazil.201323874441
knowledge and prevalence of viral hepatitis among beauticians.beauty treatments, such as tattooing, piercing, manicures, pedicures, and barbershop shaving, can pose an important risk of virus transmission. this study was conducted to determine hepatitis a virus (hav), hepatitis b virus (hbv), and hepatitis c virus (hcv) prevalence in a sample of beauticians from rio de janeiro (southeast brazil) and to assess the knowledge and attitudes of these professionals regarding viral hepatitis and their practices during their activities. one hundred nineteen beauti ...201424916521
tuberculosis in renal transplants in rio de janeiro.retrospective analysis of 982 renal transplants over 21 years (1981 to 2002) sought to evaluate the prevalence of tuberculosis (tb). this analysis included 74 patients: 30 with a past tb history, who had inh prophylaxis since the beginning of immunosuppression, and 44 who only became tb infected after receiving transplants. the diagnosis of tb was made by a compatible medical situation with bacteriological/histological confirmation, which when not possible, underwent a therapeutic test occur. th ...200415194311
[prevalence of hepatitis c in patients with systemic lupus erythematosus in the hospital of federal university of rio de janeiro (huccf)].patients with systemic lupus erythematosus (sle) are at risk for the acquisition of hepatitis c, owing to frequent hospitalization and hemotransfusion. many clinical and laboratory manifestations related to auto-immunity are shared between lupus and hcv infected patients.201612185635
prevalence of hepatitis b and c markers in a population of an urban university in rio de janeiro, brazil: a cross-sectional study.epidemics of hepatitis b and c are a public health burden, and their prevalence in brazil varies among regions. we determined the prevalence of hepatitis markers in an urban university population in order to support the development of a comprehensive program for hbv immunization and hbv/hcv diagnosis. students, employees, and visitors (n = 2,936, 31 years iqr 24.5-50, female = 69.0% and 81.1% with at least 12 years of education) were enrolled from may to november 2013. antibodies against hepatit ...201526436353
improved virologic outcomes over time for hiv-infected patients on antiretroviral therapy in a cohort from rio de janeiro, 1997-2011.previous cohort studies have demonstrated the beneficial effects of antiretroviral therapy (art) on viral load suppression. we aimed to examine the factors associated with virologic suppression for hiv-infected patients on art receiving care at the evandro chagas clinical research institute, oswaldo cruz foundation in rio de janeiro, brazil.201424919778
clinical and therapeutic features of pulmonary nontuberculous mycobacterial disease, brazil, 1993-2011.to identify clinical and therapeutic features of pulmonary nontuberculous mycobacterial (pntm) disease, we conducted a retrospective analysis of patients referred to the brazilian reference center, oswaldo cruz foundation, rio de janeiro, brazil, who received a diagnosis of pntm during 1993–2011 with at least 1 respiratory culture positive for ntm. associated conditions included bronchiectasis (21.8%), chronic obstructive pulmonary disease (20.7%), cardiovascular disease (15.5%), aids (9.8%), di ...201323745217
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