Publications

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[frequency of occurrence of hepatitis c virus markers and risk factors among hospital personnel in the novosibirsk region].the occurrence of markers, the genotypic variety of isolates and the profile of risk factors with respect to viral hepatitis c among 629 employees of the regional clinical hospital (rch) in novosibirsk and 1,020 employees of the central district hospital (cdh) in iskitim were studied in a cross-sectional investigation. the occurrence of hepatitis c virus (hcv) markers was 5.1% in rch and 2.2% in cdh. among the risk factors in the population under study were: the medical history of blood transfus ...200212043148
[occurrence of markers, distribution of genotypes and risk factors for viral hepatitis c among some groups of the population in the novosibirsk region].the occurrence of markers, genotypic variability of isolates and risk factors for viral hepatitis c (hcv) were studied in 4 groups of residents of the novosibirsk region (altogether 2,000 persons). anti-hcv igg were detected within the range from 4.6% among medical personnel to 48% among the patients of the drug-abuse clinic. the detection rate of hcv rna in seropositive samples varied from 79.3% to 86.3%. the determination of genotype was carried out for 388 isolates: 1b--50.3%, 2a--4.4%, 2c--0 ...200415554307
[the occurrence rate of hgv/gbv-c rna and risk factors in patients of narcological dispensary in novosibirsk].the occurrence rate of hgv/gbv-c rna, genotypic variety of isolates and various risk factors of infection with hgv/gbv-c were evaluated in 500 patients of the narcological dispensary of novosibirsk. the occurrence rate of hgv/gbv-c rna among all examined blood sera was 33.6%. at the same time in blood sera with hcv markers the occurrence rate of hgv/ gbv-c was 42.9% and in sera with negative results for markers hcv--25%. for gene typing of obtained isolates the direct sequencing of the amplifica ...200515881934
hiv prevalence and risk behavior among injection drug users and their sex partners in two russian cities.the hiv epidemic in russia remains concentrated mostly among injection drug users (idus). little is known about the extent to which sexual partnerships are the bridge between idus and the general population and create the potential for generalizing the epidemic. idus in two russian cities, novosibirsk and ivanovo (n=593), were recruited via respondent-driven sampling. a modified one-step snowball strategy was used to recruit idu's sex partners who do not themselves use drugs (pidu, n=82). sexual ...201323186172
association of il28b and il10 gene polymorphism with predisposition to tick-borne encephalitis in a russian population.genetic predisposition to tick-borne encephalitis (tbe) is rather poorly studied in human populations. human genes encoding crucial components of antiviral immune response are most likely involved in protective mechanisms against tbe virus. previously, several single nucleotide polymorphisms (snps) located in interleukin 28b (il28b) and interleukin 10 (il10) genes were associated with predisposition to chronic hepatitis c (caused by a structurally similar virus from the same flaviviridae family) ...201627068548
association between polymorphisms in oas2 and cd209 genes and predisposition to chronic hepatitis c in russian population.chronic hepatitis c is a severe liver disease caused by positive-strand rna virus. previously, we reported an association between seven single nucleotide polymorphisms (snps) in four innate immunity genes (oas2, oas3, cd209, and tlr3) and human predisposition to tick-borne encephalitis, caused by a virus from the same flaviviridae family, in a russian population. currently, genotype and allele frequencies for these snps were analyzed in 75 chronic hepatitis c patients and compared with the popul ...201424594345
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