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[study results and the unresolved problems in the epidemiology and prevention of parenteral viral hepatitis in russia].great differences in the activity of the epidemic process of hepatitis b (hb), the occurrence of hbsag among the population of different regions of russia (in the central and northwestern regions among 1.8-2.4% of the population, in tuva among 9.8% of the population, in yakutia among 11.6% of the population) and considerable differences in the occurrence of hbeag among hbsag carriers in these regions (antibodies to delta virus have been detected in 1.3-5.5% of carriers of this antigen in the eur ...19947879476
[the hepatitis c virus infection of moscow blood donors].a total of 1331 persons aged 18-53 years were screened for specific markers of hepatitis c virus (hcv) and hepatitis b virus (hbv) infections in their blood, among them 656 primary blood donors, 256 plasmapheresis donors, 111 hbsag carriers and 306 primary donors with only anti-hbc in the blood. according to the results of assays obtained with the use of assay systems ortho elisa and abbott hcv eia (usa), the detection rate of anti-hcv-c100-3 among primary blood donors in moscow was 1.37% and wa ...19938067123
[the hepatitis c viral infection of the medical workers and patients at hemodialysis units in moscow].the results indicating the same capacity of commercial "ortho" hcv-elisa and "abbott" hcv eia tests in detecting antibodies to hepatitis c virus (anti-hcv-c100-3) were obtained. the study aimed at the detection in the blood serum of antibodies to hepatitis c virus (hcv) was carried out in 656 primary blood donors at the age of 18 to 53 years, 339 medical workers and 130 patients at the age of 16 to 63 years in three different haemodialysis wards of moscow. among 270 medical workers, anti-hcv-c10 ...19938073748
[detection of type specific antibodies to hepatitis c virus ns4 protein in hepatitis c patients by enzyme immunoassay].a multi-enzyme immmune-assay test system was designed for serotyping of genotypes hepatitis c virus (hcv) and a method of such typing of the serum of patients with hepatitis c was worked out. the above test-system was worked out on the basis of a study of 10 type-specific peptides modeling different fragments from ns4-protein variable region of hcv. the designed test system was evaluated by using a set of 42 serum samples obtained at random from patients with chronic hepatitis c, which had been ...200312894478
[a category of patients with tuberculosis concomitant with hiv infection in an anti-tb facility].a category of patients with tuberculosis concomitant with hiv infection, who were admitted for inpatient care to the infection department of tuberculosis clinical hospital no. 7, moscow, during 1996-2001, was analyzed. peculiarities of the mentioned patients' category (205 subjects) were studied at the anti-tb facility. it was established that males (83.4%), aged 21-30 (48.9%), as well as unemployed (71%) prevailed. as much as 14% of them were homeless and 33% had a prison history. drug-addictio ...200312899005
[genetic variations of hepatitis c virus circulating in the ural region].a study of distributions of different genetic variations (subtypes) of hepatitis c virus (hcv), circulating in the territories of yekaterinburg and chelyabinsk among infected population categories of different social statuses and age, is reported in the paper. the predominance of 1b subtype was shown in the hcv-infected patients at the hemodialysis center (hdc) and at the pediatric oncohematology center (ohc), 83.3% and 84.6% respectively. the summarized results of examinations of patients condu ...200314598474
molecular epidemiology of hepatitis b, c, d and e viruses among children in moscow, russia.it is known that the prevalence of hbv and hcv infections vary according to geographical areas. however, in russia, an adequate level of information on the molecular epidemiology of hepatitis viruses has not been available so far.200415072755
prevalence of hiv, hepatitis c and syphilis among injecting drug users in russia: a multi-city study.to estimate the prevalence of hiv, hepatitis c virus (hcv) and syphilis in injecting drug users (idus) in russia.200616445554
[evaluation of the efficiency of external assessment of the quality of determining antibodies to hepatitis c virus in the network of screening laboratories].a regional external quality assessment (eqa) system for determining anti-hepatitis c virus (hcv) was developed and introduced. for this, a control panel comprising 14 samples with anti-hcv and 6 samples without anti-hcv was tested in the reference laboratory of moscow infectious hospital one. a total of 6 sessions were conducted with the participation of 8 laboratories. the regional eqa system covering a limited number of laboratories was shown to significantly improve the quality of detection o ...200818318137
[hepatitis virus genotype structure in patients with chronic hepatitis c].studies of hepatitis c virus (hcv) genotype and subtype structure in patients with chronic hepatitis c in 3 regions of the central federal district of russia.201121809642
[spectrum, clinical features, diagnosis of opportunistic and comorbid pathology in hiv-infected patients admitted to infection hospital of moscow].to analyse structure, clinical features, diagnosis of opportunistic and concomitant diseases in patients with hiv infection admitted to infection hospital of moscow.200819143183
drug injecting and syringe use in the hiv risk environment of russian penitentiary institutions: qualitative study.evidence highlights the prison as a high risk environment in relation to human immunodeficiency virus (hiv) and hepatitis c virus (hcv) transmission associated with injecting drug use.200617156178
[the verification of the results of screening antibodies to hepatitis c virus in blood donors].6,744 persons were examined for the presence of antibodies to hepatitis c virus (hcv) before blood donation (4,219 persons in moscow and 2,525 persons in st. petersburg). the serum samples found to contain antibodies to hcv were additionally studied by the immunoblot techniques. the positive results of antibody screening were registered in 78 persons: 26 persons in moscow (0.62%) and 52 in st. petersburg (2.05%). in both cities the positive results of screening were confirmed in 62% of cases. di ...200516279540
[changes of humoral and cellular immunity in chronic hepatitis c patients of different staging].the purpose of the present study was to investigate the influence produced by viral proteins in the hepatic cells and rna of hepatitis c virus (hcv) on the indices of t- and b-cell response in 52 patients with chronic hepatitis c (chc). a relative count of peripheral-blood lymphocytes (pbl), expressing antigens cd3+, cd4+, cd8+, cd16+, cd20+ and cd95+ was estimated. the repertoire of antibodies to hcv proteins was specified. the thus obtained data were compared with an activity and a disease sta ...200312894474
significance of sexual route of transmission of hepatitis b and c in russia.it is generally understood that hepatitis b and hepatitis c may be sexually transmitted. during the last decade there was a sharp growth of hepatitis b and c in russia. in comparison to 1992 the incidence of hepatitis b in russia rose two-fold and in 1999 there were 43.31 cases per 100,000 of population (in some cities up to 150/100,000 and even more). the incidence of hepatitis c in 1999 (19.31 per 100,000 of population) rose to six times more than in 1994. at the same time there was a dramatic ...200212537718
[the detectability of the hepatitis b surface antigen and antibodies to the hepatitis c virus in serviceman blood donors].blood tests on hbsag and anti-hcv were conducted in two groups of donors. the first group: 13677 servicemen, average age--20, constant place of residence--different regions of russia. the second group: 1810 men (70%) and women (30%), average age--37, moscow residence. in comparison with 1991 a reduction of positive hbsag test results was marked in 1992 (by 1.6%) and in 1993 (by 1.8%), including 1.6 and 1.8% for combat units, and 2.2 and 3.9% for military construction units. in the authors' opini ...19948191692
[the spread of hepatitis c markers among the population of regions of russia and central asia].a total of 2,217 blood serum samples taken from the population of some regions of the former ussr were studied for the presence of antibodies to hepatitis c virus (hcv) with the use of a commercial enzyme immunoassay system (obtained from ortho, japan). perceptible changes in the detection rate of these antibodies throughout the territory of the former ussr were established. most frequently anti-hcv antibodies were detected among the population of the republics of central asia (5.3-2.9%), as wel ...19938067143
[the problem of viral hepatitis c in the russian federation].the incidence of chronic viral hepatitides (cvh) has increased 2.2-fold in the russian federation over the past decade. this increase is mainly determined by an almost threefold rise in the incidence of chronic hepatitis c (chc): from 12.9 in 1999 to 39.1 per 100,000 population in 2012. the calculated data of hepatitis c burden in the russian federation show that in 2010 the total medical and social losses and expenses associated with hepatitis c and its implications were 48.47 billion rubles or ...201425509897
[frequency of detection of different hepatitis c virus subtypes in the moscow region].there is a high degree of the hepatitis c virus (hcv) infection in moscow region. the analysis of different hcv subtypes is caused by the necessity of prognostic estimation of predominant subtypes for the near future because new schemes of antiviral therapy for several hcv genotypes are developed. it is established that subtype 1b (52.1%) prevails in moscow region. the increase of subtype 3a (37.2%) against the decrease in subtype 1b is observed. in patients infected before 1990 hcv subtype 1b i ...201623785760
male sex workers in moscow, russia: a pilot study of demographics, substance use patterns, and prevalence of hiv-1 and sexually transmitted infections.the russian federation has been undergoing a concentrated epidemic of hiv-1 with high rates of infection among injecting drug users. less is known about the relative risk and contribution to the country's hiv epidemic by other at-risk populations including sex workers and men who have sex with men. the goals of this project were to explore demographic characteristics, substance use patterns, and estimate the prevalence of sexually transmitted infections (stis) and high-risk behaviors among male ...201020390488
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