| primary liver cancer incidence-rates related to hepatitis-c virus infection: a correlational study in osaka, japan. | osaka, japan, has one of the highest, primary liver cancer (plc) incidence-rates in the world, although hepatitis-b virus (hbv) is not endemic. this paper addresses the question of whether the plc-incidence variation within osaka prefecture is due to differences in the prevalence of hepatitis-c virus (hcv) infection. the screening data of antibody to hcv (anti-hcv) and of hepatitis-b virus antigen (hbsag) in 111,069 male blood-donors, and the incidence data of male plc obtained from the osaka ca ... | 1994 | 7510133 |
| [molecular epidemiology of infection by hepatitis c virus in the airin district of osaka city]. | | 1995 | 7563760 |
| prevalence of second generation antibody to hepatitis c virus among voluntary blood donors in osaka, japan. | to clarify the demographic characteristics of the prevalence of hepatitis c virus (hcv) infection in osaka, japan, where hepatocellular carcinoma is common, we investigated the screening data of antibody to hcv (anti-hcv, dainabothcvpha, second generation assay) in 197,600 voluntary blood donors residing in osaka. the study found that age-standardized prevalence of anti-hcv was significantly higher than that of hbsag (2.25 cf 0.86 percent among males, p < 0.001; 2.17 cf 0.55 percent among female ... | 1994 | 7999962 |
| case-control study of hepatocellular carcinoma among koreans living in osaka, japan. | mortality rates from liver cancer among koreans living in osaka are 2-3 times higher than those among japanese. our previous study revealed that chronic hepatitis b virus (hbv) infection and excessive alcohol drinking are two major risk factors for hepatocellular carcinoma (hcc) among koreans in osaka, although more than 70% of the hcc cases were negative for hepatitis b surface antigen (hbsag). using a recently developed immunoassay for detecting serum hepatitis c virus antibody (hcv-ab), the r ... | 1994 | 8071108 |
| hepatitis c virus 1b(ii) infection and development of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma: a case-control study in japan. | this study was performed to determine the distribution of hepatitis c virus (hcv) genotypes among asymptomatic carriers (asc) and patients with chronic hepatitis without cirrhosis (nc-ch), liver cirrhosis (lc), and hepatocellular carcinoma (hcc) in the osaka area, and to assess whether infection with hcv genotype 1b (ii) is more likely to develop into hepatocellular carcinoma (hcc) than is that with genotype 2a (iii) or genotype 2b (iv). genotypes of all study subjects were determined by okamoto ... | 1998 | 9816816 |
| the risk of hepatitis c virus infection among blood donors in osaka, japan. | to estimate the risk of hepatitis c virus (hcv) infection among blood donors, we conducted a retrospective cohort study with 448,020 hcv-seronegative donors who donated blood more than once between february 1992 and july 1997 in osaka (a total of 2,676,738 allogeneic blood donations). the donors were divided into four age groups according to the age at the initial donation: group a (16-24 years), group b (25-34 years), group c (35-49 years) and group d (50-64 years). fifty-nine donors became inf ... | 1998 | 9884479 |
| risk of non-hodgkin's lymphoma in patients with hepatitis c virus infection. | hepatitis c virus (hcv) has been suggested to play an etiological role in the development of b-cell non-hodgkin's lymphoma (nhl) in italy. however, another study in scotland questioned increased risk of development of nhl in patients with chronic hcv infection. a total of 2,162 patients admitted to 3 hospitals in osaka, where the incidence of hcv-related hepatitis is highest in japan, during the period from 1957 to 1997 were followed up from the date of diagnosis of chronic hcv-related hepatitis ... | 1999 | 9935205 |
| homeless patients with hepatocellular carcinoma in osaka city, japan. | although the number of homeless persons is increasing worldwide, studies delineating the health status of these persons according to various medical perspectives, including hepatology, are limited. however, such studies are important for understanding the pathogenesis of diseases and their prevention. | 1999 | 10370675 |
| prospective study on the risk of hepatocellular carcinoma among hepatitis c virus-positive blood donors focusing on demographic factors, alanine aminotransferase level at donation and interaction with hepatitis b virus. | the risk for hepatocellular carcinoma (hcc) among asymptomatic hepatitis c virus (hcv) carriers is not well understood. a community-based prospective study was conducted for over 8 years by record linkage to the osaka cancer registry. the subjects were 1,927 individuals who were positive for anti-hcv through screening for second-generation hcv antibody (passive hemagglutination assay: >or= 2(12)) in voluntary blood donation. the risk factors for hcc and interaction between hcv and hepatitis b vi ... | 2004 | 15386355 |
| liver cancer risk in japanese male dentists: a long-term retrospective cohort study. | it has been speculated that dentists are at high risk for occupational exposure to bloodborne viruses such as hepatitis b and hepatitis c viruses. to assess the risk of the development of liver cancer among japanese male dentists, we conducted a retrospective cohort study on 3,314 dentists of the osaka dental association who were members between 1964 and 1985, the year before hbv immunization became available. by linking to the osaka cancer registry, we found that during the period of 1964-1997, ... | 2004 | 15492457 |
| [present status of community-based hcv screening in osaka city and evaluation of the utility of follow-up programs on hepatitis]. | the present status of community-based hcv screening in osaka city and the utility of follow-up programs on hepatitis were examined. | 2008 | 18404888 |
| declining incidence of hepatocellular carcinoma in osaka, japan, from 1990 to 2003. | japan has the highest incidence rate of primary liver cancer attributed to chronic hepatitis c virus (hcv) infection among developed countries. molecular clock analysis of hcv sequences revealed that the spread of hcv took place earlier in japan than in other countries. this might influence recent temporal trends in hepatocellular carcinoma (hcc) incidence. | 2008 | 18519928 |
| statbite: hepatitis c virus-related hepatocellular carcinoma incidence among men in osaka. | | 2008 | 18612126 |
| risk factors for intrahepatic cholangiocarcinoma: a possible role of hepatitis b virus. | there are several established risk factors for intrahepatic cholangiocarcinoma (icc), namely primary sclerosing cholangitis, fibropolycystic liver disease, parasitic infection, intrahepatic biliary stones and chemical carcinogen exposure. however, the majority of patients with icc do not have any of these risk factors. therefore, identification of other risk factors is warranted for the prevention and early detection of icc. we evaluated the risk factors for icc in a large-scale cohort study in ... | 2010 | 20002305 |