| [investigation of anti-hepatitis c virus in the sera of different populations of beijing]. | a study of anti-hcv in the sera of different populations of beijing was conducted. of the general population, 2.1% (9/438) were anti-hcv positive, and of the patients that underwent blood transfusion 11.1% (6/54) were anti-hcv positive. among patients with chronic liver diseases, anti-hcv was positive in 10.5% (36/342) of patients with chronic persistent hepatitis (cph), 12.1% (13/107) of those with chronic active hepatitis (cah), 42.6% (63/148) of those with liver cirrhosis (lc) and 38.4% (20/5 ... | 1992 | 1374286 |
| preliminary report on seroepidemiology of hcv and hbv infection in northern china. | 1 141 serum samples from various population groups in north china were examined for c100-3ab by elisa. antibody to c100-3 antigen derived from hcv genome (c100-3a) and hbsag were measured in 438 normal population in beijing. the c100-3ab positive rate was 2.1% and the hbsag positive rate was 2.5%. there is increased occurrence with age. in 649 cases of chronic liver diseases, the hbsag positive rate was 87.1% in chronic persistent hepatitis (cpa), 88.8% in chronic active hepatitis (cah), 64.9% i ... | 1992 | 1395840 |
| virological features of hepatitis c virus infection in patients with liver diseases in the inshore area of the yangtze river. | the prevalence, genotypes, coinfection and putative core gene sequence of hepatitis c virus (hcv) were investigated in the inshore area of the yangtze river, where hepatocellular carcinoma (hcc) is thought to be very common. most patients with liver diseases were infected with hepatitis b virus (hbv), but the incidence of anti-hcv was very low, being 3.4% in patients with acute hepatitis, and approximately 7% in those with chronic liver diseases. the rate of coinfection with hbv and hcv in patie ... | 1994 | 7524191 |
| hepatitis c virus rna and antibodies among blood donors in beijing. | blood units from voluntary as well as commercial donors in beijing, china, were tested for hepatitis c virus rna and antibodies, and for serological markers of hepatitis b virus infection. hcv rna was detected less frequently in 1909 voluntary donors (5 (0.3%)), than in 1017 commercial donors (58 (5.7%)) (p < 0.001). antibody to hepatitis c virus was detected by the second-generation enzyme immunoassay in 55 (87%) of 63 blood units with viremia. evidence of present or past infection with hepatit ... | 1994 | 7529274 |
| [a preliminary report on the prevalence of different types of hepatitis in adult patients with acute sporadic hepatitis in beijing area]. | in order to investigate the prevalence of different types of viral hepatitis in beijing area, the markers of viral hepatitis a, b, c and e were detected on 72 adult patients with acute viral hepatitis in the infectious diseases department of our hospital. the results showed that 26.4% of the cases had hav infection, 8.3% hbv infection, 18.1% hcv infection and 31.9% hev infection. it is shown that the prevalence of hev infection in beijing area is high. | 1993 | 8269760 |
| prevalence, genotypes, and an isolate (hc-c2) of hepatitis c virus in chinese patients with liver disease. | china has not been extensively investigated for the prevalence of hepatitis c virus (hcv) infection among people with or without liver disease. we analyzed serum from 2,177 liver disease patients from 7 cities in different areas of china. of 435 acute hepatitis patients, only 11% were positive for hcv rna, while hepatitis b surface antigen (hbsag) was detected in 33%. of 1,668 patients with chronic liver disease, 14% and 74% were positive for hcv rna and hbsag, respectively. nearly 80% of non-b ... | 1993 | 8394876 |
| infection with gb virus c and hepatitis c virus in hemodialysis patients and blood donors in beijing. | rnas of gb virus c (gbv-c) and hepatitis c virus (hcv) were sought by reverse-transcription polymerase chain reaction with nested primers deduced from the 5' untranslated region: 79 patients on maintenance hemodialysis, 205 commercial blood donors, and 205 voluntary donors in beijing were studied. gbv-c rna was detected in 43 (54%) patients and 17 (8%) commercial donors, and hcv rna in 43 (54%) patients and 13 (6%) commercial donors, respectively. by contrast, gbv-c rna was detected only in 2 (1 ... | 1997 | 9131454 |
| prevalence of hepatitis c virus infection in nanjing, southern china. | there is little information on the prevalence of hepatitis c virus (hcv) infection in china. the prevalence of hcv infection was determined in 998 subjects (398 with liver disease and 600 without) in the city of nanjing in southern china. subjects were tested for anti-hcv antibodies by a second generation assay. we also determined serological hcv genotypes and hcv rna sequences. among the 600 subjects without liver disease, 3 (0.5%) were seroreactive for anti-hcv. all were less than 12 years of ... | 1997 | 9258561 |
| hepatitis g virus infection in screened chinese blood donors. | to determine the prevalence of the recently identified hepatitis g virus (hgv)/gbv-c in screened chinese paid blood donors. | 1998 | 9481862 |
| [a prospective study on post-transfusion hepatitis c]. | a cooperative prospective study on the clinical epidemiology of post-transfusion hepatitis c virus (hcv) infection was carried out from april 1993 to november 1994 in four medical schools in china, namely, peking union medical college (pumc), western china medical university (wcmu), shanghai medical university (smu) and beijing medical university (bmu). a screen test on anti-hcv was done for the healthy donors of four groups. anti-hcv positive rate was found to be 14.49% in professional blood do ... | 1996 | 9592324 |
| urban-rural comparison of hbv and hcv infection prevalence in eastern china. | the present study was initiated to make an urban-rural comparison of the prevalence of cases positive to hepatitis b and c virus (hbv and hcv, respectively) infection markers in densely populated eastern half of china. for this purpose, 10 survey siles were selected, i.e., six sites in urban areas (the city group; beijing, shanghai and four provincial capitals) and four sites in rural areas (the village group; one village each in jilin and shandong provinces, and two villages in shaanxi province ... | 2000 | 11351857 |
| [a prevalence study on hepatitis c infection in 4,055 healthy children of beijing]. | to understand the prevalence of hepatitis c (hc) infection in children of urban beijing. | 1999 | 11864475 |
| [detection of anti-hav, anti-hbv, anti-hcv and anti-hev antibodies in the patients with sporadic acute hepatitis in beijing during 1995-2000]. | to investigate distribution of acute hepatitis a, hepatitis b, hepatitis c and hepatitis e in beijing area. | 2001 | 11986727 |
| dominant role of hepatitis b virus and cofactor role of aflatoxin in hepatocarcinogenesis in qidong, china. | we assessed the separate and combined effects of hepatitis b virus (hbv), hepatitis c virus (hcv), and aflatoxin in causing hepatocellular carcinoma (hcc) in qidong, china. a consecutive series of 181 pathologic-diagnosed hcc cases were studied for hepatitis b surface antigen (hbsag), anti-hbc, hbv x gene sequence, anti-hcv, the 249ser-p53 mutation, and chronic hepatitis pathology. each of the 181 incident hcc cases had markers for hbv infection and hepatitis pathology; only 6 of 119 cases were ... | 2002 | 12395332 |
| [detection of hepatitis g virus infection among clinical patients with hepatitis/liver diseases in china by reverse transcription-nested polymerase chain reaction]. | according to two highly conserved genome sequences within the helicase(ns3) region and 5'-uncoding(5' utr) region, we designed two sets of primer pairs to detect hgv rna by rt-nested pcr in order to study hgv infection in chinese population. three hundred and fifty-four serum specimens of various liver diseases were collected from beijing, qin huangdao and henan areas. seventy-nine out of 354(22.3%) specimens were hgv rna positive. among 254 known clinical hepatitis/liver disease samples, 50(19. ... | 1998 | 12515201 |
| [study on the epidemiology and distribution of human immunodeficiency virus-1 and hepatitis c virus infection among intravenous drug users and illegal blood donors in china]. | to determine the epidemiologic features and distribution of human immunodeficiency virus-1 (hiv-1) and hepatitis c virus (hcv) infection among intravenous drug users and illegal blood donors in china. | 2003 | 14687492 |
| tight association of hepatocellular carcinoma with hbv infection in north china. | hepatocellular carcinoma (hcc) is the second most common cancer in china. hepatitis b and c viruses (hbv and hcv) and aflatoxins are known risk factors for hcc, but the etiological status of these factors in hcc development is not clear. this study was undertaken to define the absolute importance of hbv in hepatocarcinogenesis of north china. | 2005 | 15730918 |
| evaluation of international classification criteria (2002) for primary sjögren's syndrome in chinese patients. | to evaluate the sensitivity and specificity of international classification criteria (2002) for primary sjögren's syndrome (pss) and the role of lower lip biopsy in diagnosis of pss in chinese patients. | 2005 | 16261891 |
| trends in prevalence of hiv, syphilis, hepatitis c, hepatitis b, and sexual risk behavior among men who have sex with men. results of 3 consecutive respondent-driven sampling surveys in beijing, 2004 through 2006. | studies tracking trends in hiv prevalence and risk behavior among men who have sex with men (msm) in china are rare. we report on 3 consecutive cross-sectional surveys measuring the prevalence of hiv, other infectious diseases, and related risk behavior among msm in beijing in 2004, 2005, and 2006. | 2007 | 17577125 |
| distinctive rheumatic manifestations in 98 patients with human immunodeficiency virus infection in china. | to analyze the spectrum and risk factors of rheumatic manifestations in patients with human immunodeficiency virus (hiv) infection. | 2007 | 17659750 |
| risk factors of hiv infection and prevalence of co-infections among men who have sex with men in beijing, china. | to investigate risk factors related to hiv infection and the prevalence of selected infections, especially sexually transmitted infections (sti) among men who have sex with men (msm). | 2007 | 18172392 |
| risk factors for hepatitis c virus infection among blood donors in beijing and implications for improving the pretesting donor screening process. | the objective was to determine risk factors of hepatitis c virus (hcv) infection in blood donors in beijing. | 2008 | 18346015 |
| risk factors for syphilis and prevalence of hiv, hepatitis b and c among men who have sex with men in beijing, china: implications for hiv prevention. | to examine the correlates for syphilis and the prevalence for hiv, hepatitis b, hepatitis c among men-who-have-sex-with-men (msm) in beijing, china. a total of 541 msm was recruited using peer-referral, community outreach, and internet. questionnaire-based interviews provided information including, demographics, sexual and other risk behaviors. hiv prevalence was 4.8%, syphilis 19.8%, hcv 0.4% and hbsag 6.5%. the median number of lifetime male sex partners was ten. in the past 3 months, 20.7% dr ... | 2009 | 19082879 |
| [epidemiological characteristics and prevention strategies of viral hepatitis in chongwen district of beijing during 1997-2006]. | to understand the epidemiological features of viral hepatitis, and provide scientific evidence for developing strategies for prevention and control. | 2008 | 19115624 |
| incidence of hiv-1, syphilis, hepatitis b, and hepatitis c virus infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men in beijing, china. | to investigate the incidence of hiv-1, syphilis, hepatitis b virus (hbv), and hepatitis c virus (hcv) infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men (msm) in beijing, china. | 2009 | 19710617 |
| [study on the relationship between behavioral factors, psychological status and hiv infection among men who have sex with men in beijing.]. | to study the prevalence and risk factors of human immunodeficiency virus (hiv) among men who have sex with men (msm) in beijing. | 2010 | 20510051 |
| double-antigen sandwich elisa for the detection of anti-hepatitis c virus antibodies. | a double-antigen sandwich elisa was developed a detection of hcv antibodies by a recombinant multi-epitope hcv antigen and a biotin-streptavidin amplification system. three plasma specimens from 1708 individuals who were suspected previously to be hcv-positive using an hcv antibody diagnostic kit (chuangxin, xiamen, china) displayed negative results when using the elisa. these results were validated by a recombinant immunoblotting assay (two were negative, and one was indeterminate). among 889 b ... | 2010 | 21029749 |
| The Investigation of HIV and HCV Infection and Risk Factors among Opiate Drug Users in Beijing, China. | Objective: To explore the prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) and the risk factors among opiate drug users in Beijing. Methods: The opiate drug users enrolled in methadone maintenance treatment clinics of Beijing from 30 November 2004 to 31 March 2008 were investigated. The blood samples were collected and tested for HIV and HCV infection and questionnaires were used for all subjects admitted. Results: Among 1211 eligible subjects, 12 HIV and 713 HCV-posi ... | 2011 | 22175771 |
| [hepatitis c viruses infection situation in the human population of six provinces in china]. | to investigate the seroprevalence of hepatitis c viruse infection in the human population in six regions of beijing, heilongjiang, shandong, ningxia, gansu and sichuan in china. | 2011 | 22734232 |
| seroprevalence of the hepatitis b, hepatitis c, and human immunodeficiency viruses and treponema pallidum at the beijing general hospital from 2010 to 2014: a cross-sectional study. | the hepatitis b, hepatitis c, human immunodeficiency viruses and treponema pallidum are important causes of infectious diseases concern to public health. | 2015 | 26502175 |
| hepatitis c virus subtype and evolution characteristic among drug users, men who have sex with men, and the general population in beijing, china. | the aim of this study was to characterize the current molecular epidemiology of hepatitis c virus (hcv) infection and evaluate the evolutionary patterns of hcv subtypes in beijing, china, among different subpopulations.the whole blood samples and behavioral data were collected from a total of 10,354 subjects, including drug users (dus), men who have sex with men (msm), and the general population, in beijing from 2010 to 2011. samples were tested for hcv infection using both enzyme-linked immunos ... | 0 | 26871798 |
| quality control and evaluation of vaccines in china. | i was born in luoyang in 1963, a city in china with thousands of years' history. the city is the eastern starting point of the silk road (bc 206-260 ad), a famous and long trade route in human history. living in this ancient city, i grew up under the influence and impact of chinese traditional culture. when i was a teenager, i once read a book "yellow emperor's inner canon" (huang di nei jing, written about 5th century bc), which is the oldest extant classic of traditional chinese medicine. i wa ... | 2014 | 24663039 |
| extrahepatic manifestations of chronic hepatitis c virus infection: 297 cases from a tertiary medical center in beijing, china. | chronic hepatitis c virus (hcv) infection can affect multiple organ systems and cause a variety of extrahepatic manifestations (ems). we sought to assess the constituent ratio of ems in chinese patients with chronic hcv infection and identify the clinical and biological factors associated with em. | 2014 | 24709167 |
| prevalence and risk factors of hepatitis c and b virus infections in hemodialysis patients and their spouses: a multicenter study in beijing, china. | hemodialysis patients are at risk for hepatitis c and b virus infections. this study investigated the prevalences and risk factors of hcv and hbv infection and the distribution of hcv genotypes among hemodialysis patients and their spouses. from august to november 2011, a cross-sectional study was conducted on 20 hemodialysis units in beijing to investigate prevalences and risk factors for markers of hcv and hbv among 2,120 patients and 409 spouses. in hemodialysis patients, prevalences of anti- ... | 2013 | 23341370 |
| high prevalence of hiv, syphilis and hcv, and low methadone maintenance treatment in a migrant population in beijing. | to provide evidence for policy makers for human immunodeficiency virus (hiv) prevention and control, we investigated hiv, syphilis, and hepatitis c virus (hcv) infection and the availability of methadone maintenance treatment (mmt) among migrant drug users in beijing. | 2012 | 23041679 |
| [the sexual behavior characteristics and std infection status of women who have sex with women in beijing]. | to study sexual behavioral characteristics, infection status of hiv and sexually transmitted infections (stds) among women who have sex with women (wsw) in beijing. | 2012 | 22943919 |
| current challenges and the management of chronic hepatitis c in mainland china. | despite decreasing prevalence, new cases of hepatitis c in china are increasing recently with growing percentage of patients who are with advanced disease, aging, or not eligible for interferon-based treatments. hepatitis c infection represents a serious public health burden. this review was based on expert's consensus during a medical forum on hepatitis sponsored by the beijing wu jie-ping medical foundation. the literature searches were conducted in pubmed and critical publications in chinese ... | 2014 | 24921215 |
| [study on the etiology of acute hepatitis hospitalized patients in beijing ditan hospital from 2002 to 2011]. | to explore the etiology of acute hepatitis hospitalized patients in beijing ditan hospital from 2002 to 2011. | 2013 | 24579471 |