Publications

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prevalence, genotypes, and an isolate (hc-c2) of hepatitis c virus in chinese patients with liver disease.china has not been extensively investigated for the prevalence of hepatitis c virus (hcv) infection among people with or without liver disease. we analyzed serum from 2,177 liver disease patients from 7 cities in different areas of china. of 435 acute hepatitis patients, only 11% were positive for hcv rna, while hepatitis b surface antigen (hbsag) was detected in 33%. of 1,668 patients with chronic liver disease, 14% and 74% were positive for hcv rna and hbsag, respectively. nearly 80% of non-b ...19938394876
[evaluation of effectiveness of hepatitis b plasma derived vaccine and a survey of hepatitis c virus infection in preschool children in chengdu, sichuan].this study was undertaken to evaluate the effectiveness of hepatitis b plasma-derived vaccine and investigate the character of hepatitis c virus infection in preschool children. the anti-hbs, hbsag and anti-hcv of 985 plasma samples were examined by elisa. the results showed that the positive rate of hbsag in the children (aged < 7 yr) in the communities was 0.89% and the effectiveness of the vaccine was 91.38%. the positive rate of anti-hbs decreased with the increase in age; the positive rate ...199911387962
associated factors in modulating aflatoxin b1-albumin adduct level in three chinese populations.to elucidate the potential factors modulating exposure to aflatoxin b1 (afb1) in three chinese populations, an epidemiologic study was conducted in fusui county and nanning city of guangxi province and chengdu city of sichuan province. the incidence rates of hepatocelluar carcinoma (hcc) for males in these three regions were 92-97 per 100,000, 32-47 per 100,000, and 21 per 100,000, respectively. eighty-nine residents from fusui, 196 residents from nanning, and 118 residents from chengdu were scr ...200515810636
[hepatitis viruses infection situation in mianyang of the sichuan province].to investigate the seroprevalence of hepatitis viruses in mianyang of the sichuan province.200819544642
hiv, syphilis, hepatitis c and risk behaviours among commercial sex male clients in sichuan province, china.commercial sex male clients (csmc) are at risk of sexually transmitted infections (sti) including hiv. this study reports the prevalence of hiv, syphilis and hepatitis c virus (hcv), a history of sti and hiv-related risk behaviours in a sample of 600 csmc in three urban areas in sichuan province, china. the risk factors for prevalent syphilis infection are also examined.201020826867
prevalence of and risk factors for hepatitis c virus infection among blood donors in chengdu, china.the objectives of the study were to estimate the prevalence of anti-hepatitis c virus (hcv) positivity among blood donors from chengdu, china, and to determine risk factors associated with infection. in this study, data were collected from volunteer blood donors between july 2006 and june 2007. anti-hcv test was performed in 119,518 donors. to identify risk factors associated with hcv infections a case-control study was conducted in 305 unique hcv-seropositive blood donors and 610 seronegative d ...201121328375
[hepatitis c viruses infection situation in the human population of six provinces in china].to investigate the seroprevalence of hepatitis c viruse infection in the human population in six regions of beijing, heilongjiang, shandong, ningxia, gansu and sichuan in china.201122734232
[a study on the prevalence rates of human immunodeficiency virus, hepatitis b virus and hepatitis c virus infections in intravenous drug users].to study hiv, hbv and hcv infections in intravenous drug users.200617299963
[study on the relationship between hepatitis c virus infection and sharing injection equipment, sexual behavior among injecting drug users].to study hepatitis c virus (hcv) transmission through different modes of sharing injection equipment and sexual behavior among injecting drug users (idus) in liangshan of sichuan province.200415231203
[hcv genotype distribution in southwest china and its influence on patients' response to pegylated-interferon α-2a plus ribavirin therapy].to study the distribution of hepatitis c virus (hcv) genotype in sichuan population and to investigate the effects of hcv genotypes on the viral response of hepatitis c patients treated with pegylated interferon α-2a plus ribavirin as well as the relationship between hcv genotype and the severity of disease.201526480661
five near full-length hepatitis c virus sequences were isolated from hiv coinfected idus of china.hiv and hcv share transmission routes including contaminated blood transfusion, sexual intercourse, and needle-sharing in injection drug users (idus). we obtained five near full-length genome sequences (nflgs) of hcv isolated from five hiv-1 coinfected idus in sichuan and xinjiang province, china. by conducting reconstruction of neighbor-joining (nj) phylogenetic tree, our results revealed that the five isolates are different genotypes (1b, 3a, 6a and 6n). the amino acid substitutions(170i) in x ...201728075146
phylogenetic analysis of hcv subgenotypes in patients from sichuan province in china based on the ns5b region.the classification of hepatitis c virus (hcv) genotypes is of clinical importance as it may help to predict drug therapy responses and estimate treatment duration. the classical method of hcv subgenotype classification is whole genome sequencing (wgs). however, the high cost and time-consuming nature of wgs limits its usage in clinical practice. a number of studies have been conducted to confirm whether specific regions of hcv could replace wgs in the classification of hcv subgenotypes. in the p ...201526311523
Seroprevalence of HIV, syphilis, and hepatitis C virus in the general population of the Liangshan Prefecture, Sichuan Province, China.This study aimed at understanding the HIV prevalence, distribution of HIV risk factors and whether the HIV has spread from high-risk groups to the general population in the Yanyuan and Muli counties, Liangshan Prefecture, Sichuan Province, China. A multistage probability method was used to select a representative sample of villages in each county, with stratification by risk employed in the sampling for the Yanyuan county. A real-name registration and confidential method were adopted to collect ...201222027998
first-time donors responding to a national disaster may be an untapped resource for the blood centre.background  on 12 may 2008, a severe earthquake struck sichuan in china. many people donated blood for the first time, leading us to question whether these donors might become repeat donors in the future. the return pattern of post-earthquake first-time donors (peftd) was compared with that of first-time donors (ftd) in a comparable period. methods  demographic characteristics, transfusion-transmissible infection rates and 1-year return rates were compared between 5147 peftd (5/13-5/19, 2008) an ...201121988212
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