Publications

the epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in amazonian brazil.	we estimate the incidence rate, serological conversion rate and basic case reproduction number (r0) of leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on marajó island, pará state, brazil. the analysis includes new methods for (1) determining the number of seropositives in cross-sectional serological data, (2) identifying seroconversions in longitudinal studies, based on both the number of antibody units and their rate of change throug ...	1997	10190170
a longitudinal study on the transmission dynamics of human leishmania (leishmania) infantum chagasi infection in amazonian brazil, with special reference to its prevalence and incidence.	this was a longitudinal study carried out during a period over 2 years with a cohort of 946 individuals of both sexes, aged 1 year and older, from an endemic area of american visceral leishmaniasis (avl) in pará state, brazil. the object was to analyze the transmission dynamics of human leishmania (leishmania) infantum chagasi infection based principally on the prevalence and incidence. for diagnosis of the infection, the indirect fluorescent antibody test (ifat) and leishmanin skin test (lst) w ...	2009	18936975
further evidences on a new diagnostic approach for monitoring human leishmania (l.) infantum chagasi infection in amazonian brazil.	this was a prospective study carried out during a period over 2 years (may/2006-september/2008) with a cohort of 1,099 individuals of both genders, aged 1 year old and older, from an endemic area of american visceral leishmaniasis (avl) in pará state, brazil. the object was to analyze the prevalence and incidence of human leishmania (l.) infantum chagasi infection as well as the dynamics evolution of its clinical-immunological profiles prior identified: (1) asymptomatic infection (ai); (2) sympt ...	2010	19946708
a prospective study on the dynamics of the clinical and immunological evolution of human leishmania (l.) infantum chagasi infection in the brazilian amazon region.	this prospective study was carried out from october 2003 to december 2005 and involved a cohort of 946 individuals of both genders, aged 1-89 years, from an endemic area for american visceral leishmaniasis (avl), in pará state, brazil. the aim of the study was to analyze the dynamics of the clinical and immunological evolution of human leishmania (l.) infantum chagasi infection represented by the following clinical-immunological profiles: asymptomatic infection (ai); symptomatic infection (si=av ...	2010	20538310
canine visceral leishmaniasis due to leishmania (l.) infantum chagasi in amazonian brazil: comparison of the parasite density from the skin, lymph node and visceral tissues between symptomatic and asymptomatic, seropositive dogs.	canine visceral leishmaniasis (cvl) is recognizable by characteristic signs of disease and is highly lethal. the infection, however, may be quite inapparent in some seropositive dogs, and this has raised the polemic question as to whether or not such animals can be a source of infection for lutzomyia longipalpis, the vector of american visceral leishmaniasis (avl). in this study we have examined 51 dogs with acute cvl from an avl area in pará state, northern brazil, and compared the parasite den ...	2010	21049230
mixed infection in the anteater tamandua tetradactyla (mammalia: pilosa) from pará state, brazil: trypanosoma cruzi, t. rangeli and leishmania infantum.	some trypanosoma and leishmania species are multi-host parasites whose distribution overlaps in several parts of the brazilian amazon basin. despite being a common trait among wild mammals, mixed infections and their consequences for the host's health and parasite transmission are still a poorly known phenomenon. here we describe a triple mixed infection - trypanosoma cruzi, t. rangeli and leishmania infantum - in a bone marrow sample from an anteater tamandua tetradactyla captured in a house ba ...	2013	23253893