Publications

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serodiagnosis and screening of canine visceral leishmaniasis in an endemic area of corsica: applicability of a direct agglutination test and immunoblot analysis.for effective control of visceral leishmaniasis caused by leishmania infantum in the mediterranean area, the detection of infected dogs is of utmost importance. to assess the suitability of a direct agglutination test (dat) and immunoblot analysis in serodiagnosis and screening of infected dogs under field conditions, a study was performed on 113 dogs in an endemic area of corsica. twenty one of 22 parasitologically confirmed cases were correctly diagnosed by both tests, and 100% specificity was ...19921471734
[first case of cutaneous leishmaniasis from leishmania infantum in corsica].canine leishmaniasis is endemic in corsica. sporadic cases of visceral leishmaniasis due to leishmania infantum have been reported in humans, but no case of cutaneous leishmaniasis has been reported to date. in august 1994, a 42-year-old woman living in orleans (france) presented with two nodular lesions on the face. these lesions appeared two months after a stay near the gulf of ajaccio in corsica. histopathological examination revealed intracellular amastigotes. the culture isolate was identif ...199810399697
isoenzymatic analysis of 712 strains of leishmania infantum in the south of france and relationship of enzymatic polymorphism to clinical and epidemiological features.in the south of france, leishmaniasis due to leishmania infantum occurs in the following five foci of endemicity (from west to east): pyrénées-orientales, cévennes, provence, côte d'azur, and corsica. between 1981 and 2002, 712 leishmania strains obtained from humans, dogs, cats, and sand flies were studied by isoenzyme analysis. in total, seven zymodemes were identified: mon-1, mon-11, mon-24, mon-29, mon-33, mon-34, and mon-108. the pyrénées-orientales focus is characterized by a predominance ...200415364993
canine leishmaniasis in south-east of france: screening of leishmania infantum antibodies (western blotting, elisa) and parasitaemia levels by pcr quantification.leishmania infantum leishmaniasis is endemic in south-east of france. the main goal of our study was to evaluate the real prevalence of asymptomatic carriage in dogs by means of real time quantitative pcr (qpcr) and serology. we included prospectively 140 military dogs wearing deltamethrine-impregnated collars. parasitaemia levels were then measured by means of quantitative real time pcr targeting kinetoplast dna with taqman chemistry. elisa and western blotting (wb) were used for serological sc ...200919720466
a twenty-year follow-up of canine leishmaniosis in three military kennels in southeastern france.canine leishmaniosis (canl) is enzootic in southeastern france, and military working dogs (mwd) posted in this area are highly exposed. to assess the efficiency of prevention, we performed a serological and clinical follow-up of 80 mwd in the var and corsica regions during the 20-year period from 1993 to 2012. the systematic and specific prevention of canl using a deltamethrin-impregnated collar (dmc) was implemented in 2002.201324499552
genetic diversity and population structure of leishmania infantum from southeastern france: evaluation using multi-locus microsatellite typing.in the south of france, leishmania infantum is responsible for numerous cases of canine leishmaniasis (canl), sporadic cases of human visceral leishmaniasis (vl) and rare cases of cutaneous and muco-cutaneous leishmaniasis (cl and mcl, respectively). several endemic areas have been clearly identified in the south of france including the pyrénées-orientales, cévennes (ce), provence (p), alpes-maritimes (am) and corsica (co). within these endemic areas, the two cities of nice (am) and marseille (p ...201626808522
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